Zebrafish Microenvironment Elevates EMT and CSC-Like Phenotype of Engrafted Prostate Cancer Cells

Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish

(2019) Chuan Yan et al.   CELL

A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis

(2019) Lanpeng Chen et al.   ONCOGENE

Zebrafish: Speeding Up the Cancer Drug Discovery Process

(2018) Patricia Letrado et al.   CANCER RESEARCH

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

(2017) Tsukasa Shibue et al.   Nature Reviews Clinical Oncology

CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer

(2017) E Zoni et al.   ONCOGENE

Cripto-1 promotes epithelial-mesenchymal transition in prostate cancer via Wnt/β-catenin signaling

(2017) Yan Liu et al.   ONCOLOGY REPORTS

Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model

(2016) Antonio Sacco et al.   CANCER RESEARCH

Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model

(2016) Claudia Tulotta et al.   Disease Models & Mechanisms

The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer

(2016) Yusuke Shiozawa et al.   Oncotarget

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

(2016) Evelyne Beerling et al.   Cell Reports

Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis

(2015) M. Ruscetti et al.   CANCER RESEARCH

Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche

(2015) Owen J. Tamplin et al.   CELL

Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer

(2014) H. D. Tran et al.   CANCER RESEARCH

Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

(2013) Christine L. Chaffer et al.   CELL

The roots of cancer: Stem cells and the basis for tumor heterogeneity

(2012) Maho Shibata et al.   BIOESSAYS

Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1

(2012) Oscar H. Ocaña et al.   CANCER CELL

Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis

(2012) Jeff H. Tsai et al.   CANCER CELL

EMT and MET in Metastasis: Where Are the Cancer Stem Cells?

(2012) Thomas Brabletz   CANCER CELL

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells

(2012) Toni Celià-Terrassa et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

(2012) Shuning He et al.   JOURNAL OF PATHOLOGY

Stem-Like Cells with Luminal Progenitor Phenotype Survive Castration in Human Prostate Cancer

(2012) Markus Germann et al.   STEM CELLS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The aldehyde dehydrogenase enzyme 7A1 is functionally involved in prostate cancer bone metastasis

(2011) Christel van den Hoogen et al.   CLINICAL & EXPERIMENTAL METASTASIS

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

The social aspects of EMT-MET plasticity

(2011) E W Thompson et al.   NATURE MEDICINE

Global Patterns of Cancer Incidence and Mortality Rates and Trends

(2010) A. Jemal et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer

(2010) Christel van den Hoogen et al.   CANCER RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL