Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1

Activation of IGF/IGF-IR signaling pathway fails to induce epithelial-mesenchymal transition in pancreatic cancer cells

(2019) E.P. Kopantzev et al.   PANCREATOLOGY

A Hierarchical Regulatory Landscape during the Multiple Stages of EMT

(2019) Nathalie Meyer-Schaller et al.   DEVELOPMENTAL CELL

Enhanced morphological and functional differences of pancreatic cancer with epithelial or mesenchymal characteristics in 3D culture

(2019) Yuuki Shichi et al.   Scientific Reports

SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferation

(2019) Vivien Freihen et al.   INTERNATIONAL JOURNAL OF CANCER

Genome-wide mapping of DNA-binding sites identifies stemness-related genes as directly repressed targets of SNAIL1 in colorectal cancer cells

(2019) Sven Beyes et al.   ONCOGENE

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

(2018) Takashi Seino et al.   Cell Stem Cell

Down-regulation of FN1 inhibits colorectal carcinogenesis by suppressing proliferation, migration, and invasion

(2018) Xun Cai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer

(2018) Anne Serrao et al.   ONCOGENE

Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells

(2018) Laia Caja et al.   ONCOGENE

TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition

(2018) Anassuya Ramachandran et al.   eLife

The Dual Role of Bone Morphogenetic Proteins in Cancer

(2018) Duc-Hiep Bach et al.   Molecular Therapy-Oncolytics

Non-redundant functions of EMT transcription factors

(2018) Marc P. Stemmler et al.   NATURE CELL BIOLOGY

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

(2018) Anushka Dongre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Statin Use After Diagnosis of Colon Cancer and Patient Survival

(2017) Philip W. Voorneveld et al.   GASTROENTEROLOGY

Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer

(2017) Barbara Jung et al.   GASTROENTEROLOGY

The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer

(2017) Steven M. Mooney et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies

(2017) Kaja C. G. Berg et al.   Molecular Cancer

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models

(2017) Peter W. Eide et al.   Scientific Reports

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

(2017) Hisham Mohammed et al.   Cell Reports

SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells

(2017) Sabine Jägle et al.   PLoS Genetics

Single-cell transcriptome analysis of avian neural crest migration reveals signatures of invasion and molecular transitions

(2017) Jason A Morrison et al.   eLife

TGF-β Tumor Suppression through a Lethal EMT

(2016) Charles J. David et al.   CELL

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo

(2016) Guangdun Peng et al.   DEVELOPMENTAL CELL

Analyzing and interpreting genome data at the network level with ConsensusPathDB

(2016) Ralf Herwig et al.   Nature Protocols

CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering

(2016) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification

(2016) Vin Yee Chung et al.   Scientific Reports

Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front

(2015) R. McLennan et al.   DEVELOPMENT

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Sequential cancer mutations in cultured human intestinal stem cells

(2015) Jarno Drost et al.   NATURE

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

(2015) Antonio Colaprico et al.   NUCLEIC ACIDS RESEARCH

CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

(2015) Manuel Stemmer et al.   PLoS One

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

(2014) D. Mouradov et al.   CANCER RESEARCH

Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK

(2014) Philip W. Voorneveld et al.   GASTROENTEROLOGY

SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer

(2014) Kerstin Rönsch et al.   Molecular Oncology

Snail Contributes to the Maintenance of Stem Cell-Like Phenotype Cells in Human Pancreatic Cancer

(2014) Wei Zhou et al.   PLoS One

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Epithelial-Mesenchymal Transition and Tumor Suppression Are Controlled by a Reciprocal Feedback Loop between ZEB1 and Grainyhead-like-2

(2013) B. Cieply et al.   CANCER RESEARCH

Regulation of epithelial to mesenchymal transition by bone morphogenetic proteins

(2013) Natasha McCormack et al.   CELLULAR SIGNALLING

Transcription Factors OVOL1 and OVOL2 Induce the Mesenchymal to Epithelial Transition in Human Cancer

(2013) Hernan Roca et al.   PLoS One

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)

(2013) R Y-J Huang et al.   Cell Death & Disease

Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing

(2012) Do Y Soung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Transcription factor Runx2 is a regulator of epithelial–mesenchymal transition and invasion in thyroid carcinomas

(2012) Dong-Feng Niu et al.   LABORATORY INVESTIGATION

Cadherin-11, a Marker of the Mesenchymal Phenotype, Regulates Glioblastoma Cell Migration and Survival In Vivo

(2012) H. Kaur et al.   MOLECULAR CANCER RESEARCH

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Meta-Analysis of Gene Expression Signatures Defining the Epithelial to Mesenchymal Transition during Cancer Progression

(2012) Christian J. Gröger et al.   PLoS One

Transcriptional Regulatory Cascades in Runx2-Dependent Bone Development

(2012) Tong Ming Liu et al.   TISSUE ENGINEERING PART B-REVIEWS

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

BMP Signaling Promotes the Growth of Primary Human Colon Carcinomas in vivo

(2010) A. Lorente-Trigos et al.   Journal of Molecular Cell Biology

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

A Colorectal Cancer Expression Profile That Includes Transforming Growth Factor β Inhibitor BAMBI Predicts Metastatic Potential

(2009) Johannes Fritzmann et al.   GASTROENTEROLOGY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition

(2009) Theresa Vincent et al.   NATURE CELL BIOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

A gene regulatory network orchestrates neural crest formation

(2008) Tatjana Sauka-Spengler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer

(2007) Liudmila L. Kodach et al.   CANCER