Functional Heterogeneity of Mouse and Human Brain OPCs: Relevance for Preclinical Studies in Multiple Sclerosis

Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age

(2019) Sonia Olivia Spitzer et al.   NEURON

How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?

(2018) Renee E. Pepper et al.   Frontiers in Cellular Neuroscience

Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis

(2017) Eva María Medina-Rodríguez et al.   Scientific Reports

ANOS1: a unified nomenclature for Kallmann syndrome 1 gene (KAL1) and anosmin-1

(2016) Fernando de Castro et al.   Briefings in Functional Genomics

Anosmin-1 over-expression regulates oligodendrocyte precursor cell proliferation, migration and myelin sheath thickness

(2015) Verónica Murcia-Belmonte et al.   Brain Structure & Function

Fibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions

(2015) Miki Furusho et al.   GLIA

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

Function and diagnostic value of Anosmin-1 in gastric cancer progression

(2015) Mitsuro Kanda et al.   INTERNATIONAL JOURNAL OF CANCER

Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration

(2015) S. Moyon et al.   JOURNAL OF NEUROSCIENCE

The Adhesion Molecule KAL-1/anosmin-1 Regulates Neurite Branching through a SAX-7/L1CAM–EGL-15/FGFR Receptor Complex

(2015) Carlos A. Díaz-Balzac et al.   Cell Reports

Early netrin-1 expression impairs central nervous system remyelination

(2014) Vanja Tepavčević et al.   ANNALS OF NEUROLOGY

Anosmin-1 over-expression increases adult neurogenesis in the subventricular zone and neuroblast migration to the olfactory bulb

(2014) Diego García-González et al.   Brain Structure & Function

NG2 cells (polydendrocytes): Listeners to the neural network with diverse properties

(2014) Robert A. Hill et al.   GLIA

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

Decreased expression of Kallmann syndrome 1 sequence gene (KAL1) contributes to oral squamous cell carcinoma progression and significantly correlates with poorly differentiated grade

(2014) Jiannan Liu et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

NG2 cells (polydendrocytes) in brain physiology and repair

(2014) Akiko Nishiyama et al.   Frontiers in Neuroscience

Heterogeneity of oligodendrocyte progenitor cells in adult human brain

(2014) Soo Yuen Leong et al.   Annals of Clinical and Translational Neurology

Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination

(2014) Hema Mohan et al.   Acta Neuropathologica Communications

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

(2013) Amanda Boyd et al.   ACTA NEUROPATHOLOGICA

Full-Length and Fragmented Netrin-1 in Multiple Sclerosis Plaques Are Inhibitors of Oligodendrocyte Precursor Cell Migration

(2013) Jenea M. Bin et al.   AMERICAN JOURNAL OF PATHOLOGY

Oligodendrocyte Progenitor Cell Susceptibility to Injury in Multiple Sclerosis

(2013) Qiao-Ling Cui et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of endogenous phosphodiesterase 7 promotes oligodendrocyte precursor differentiation and survival

(2013) E. M. Medina-Rodríguez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of oligodendrocyte precursor migration during development, in adulthood and in pathology

(2013) Fernando de Castro et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination

(2013) Yasir A. Syed et al.   EMBO Molecular Medicine

Anosmin-1 contributes to brain tumor malignancy through integrin signal pathways

(2013) Catherine T Choy et al.   ENDOCRINE-RELATED CANCER

ERK1/2 signaling is essential for the chemoattraction exerted by human FGF2 and human anosmin-1 on newborn rat and mouse OPCs via FGFR1

(2013) Verónica Murcia-Belmonte et al.   GLIA

Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury

(2013) Ji Hae Seo et al.   JOURNAL OF CLINICAL INVESTIGATION

Sonic Hedgehog Signaling Is a Positive Oligodendrocyte Regulator during Demyelination

(2013) J. Ferent et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Mechanisms regulating the development of oligodendrocytes and central nervous system myelin

(2013) S. Mitew et al.   NEUROSCIENCE

FGF2 and FGFR1 signaling regulate functional recovery following cuprizone demyelination

(2013) Amanda J. Mierzwa et al.   NEUROSCIENCE LETTERS

Protocol to Isolate a Large Amount of Functional Oligodendrocyte Precursor Cells from the Cerebral Cortex of Adult Mice and Humans

(2013) Eva María Medina-Rodríguez et al.   PLoS One

Sonic hedgehog promotes generation and maintenance of human forebrain Olig2 progenitors

(2013) J. Alberto Ortega et al.   Frontiers in Cellular Neuroscience

Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases

(2013) Takakuni Maki et al.   Frontiers in Cellular Neuroscience

Extracellular Matrix Protein Anosmin Promotes Neural Crest Formation and Regulates FGF, BMP, and WNT Activities

(2012) Yukinori Endo et al.   DEVELOPMENTAL CELL

GnRH Neuronal Migration and Olfactory Bulb Neurite Outgrowth Are Dependent on FGF Receptor 1 Signaling, Specifically via the PI3K p110α Isoform in Chick Embryo

(2012) Youli Hu et al.   ENDOCRINOLOGY

Intraventricular injection of FGF-2 promotes generation of oligodendrocyte-lineage cells in the postnatal and adult forebrain

(2012) Kasum Azim et al.   GLIA

The cysteine-rich region and the whey acidic protein domain are essential for anosmin-1 biological functions

(2012) Pedro F. Esteban et al.   JOURNAL OF NEUROCHEMISTRY

Fibroblast Growth Factor Receptor Signaling in Oligodendrocytes Regulates Myelin Sheath Thickness

(2012) M. Furusho et al.   JOURNAL OF NEUROSCIENCE

Dorsally-derived oligodendrocytes in the spinal cord contribute to axonal myelination during development and remyelination following focal demyelination

(2011) Qiang Zhu et al.   GLIA

Progenitors in the adult cerebral cortex: Cell cycle properties and regulation by physiological stimuli and injury

(2011) Christiane Simon et al.   GLIA

FGF-2 and Anosmin-1 Are Selectively Expressed in Different Types of Multiple Sclerosis Lesions

(2011) D. Clemente et al.   JOURNAL OF NEUROSCIENCE

Regenerative medicine in multiple sclerosis: Identifying pharmacological targets of adult neural stem cell differentiation

(2011) Jeffrey K. Huang et al.   NEUROCHEMISTRY INTERNATIONAL

NG2-glia as Multipotent Neural Stem Cells: Fact or Fantasy?

(2011) William D. Richardson et al.   NEURON

Anosmin-1 involved in neuronal cell migration is hypoxia inducible and cancer regulated

(2010) Bixi Jian et al.   CELL CYCLE

HR MAS MR Spectroscopy in Metabolic Characterization of Cancer

(2010) Siver Moestue et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Dynamic roles of FGF-2 and Anosmin-1 in the migration of neuronal precursors from the subventricular zone during pre- and postnatal development

(2010) Diego García-González et al.   EXPERIMENTAL NEUROLOGY

Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix

(2010) Verónica Murcia-Belmonte et al.   JOURNAL OF NEUROCHEMISTRY

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Cell cycle dynamics of NG2 cells in the postnatal and ageing brain

(2010) Konstantina Psachoulia et al.   Neuron Glia Biology

Novel Mechanisms of Fibroblast Growth Factor Receptor 1 Regulation by Extracellular Matrix Protein Anosmin-1

(2009) Youli Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic Profiling of Human Lung Cancer Tissue by1H High Resolution Magic Angle Spinning (HRMAS) NMR Spectroscopy

(2009) Cláudia M. Rocha et al.   JOURNAL OF PROTEOME RESEARCH

A novel role for anosmin-1 in the adhesion and migration of oligodendrocyte precursors

(2008) Ana Bribián et al.   Developmental Neurobiology

Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex

(2008) L. Dimou et al.   JOURNAL OF NEUROSCIENCE

Constitutively Active Akt Induces Enhanced Myelination in the CNS

(2008) A. I. Flores et al.   JOURNAL OF NEUROSCIENCE

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

(2008) Akiko Nishiyama et al.   NATURE REVIEWS NEUROSCIENCE