A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity

Broad applicability of a streamlined Ethyl Cinnamate-based clearing procedure

(2019) Wouter Masselink et al.   DEVELOPMENT

High‐resolution imaging of fluorescent whole mouse brains using stabilised organic media (sDISCO)

(2019) Christian Hahn et al.   Journal of Biophotonics

Deconvolution of light sheet microscopy recordings

(2019) Klaus Becker et al.   Scientific Reports

Ommochromes in invertebrates: biochemistry and cell biology

(2018) Florent Figon et al.   BIOLOGICAL REVIEWS

Tissue clearing of both hard and soft tissue organs with the PEGASOS method

(2018) Dian Jing et al.   CELL RESEARCH

A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing

(2018) Tatsuya C. Murakami et al.   NATURE NEUROSCIENCE

RTF: a rapid and versatile tissue optical clearing method

(2018) Tingting Yu et al.   Scientific Reports

Aqueous-based tissue clearing in crustaceans

(2018) Alu Konno et al.   Zoological Letters

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

(2018) Tobias Gerber et al.   SCIENCE

Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents

(2018) Kazuki Tainaka et al.   Cell Reports

High-resolution ultramicroscopy of the developing and adult nervous system in optically cleared Drosophila melanogaster

(2018) Marko Pende et al.   Nature Communications

EyeCi: Optical clearing and imaging of immunolabeled mouse eyes using light-sheet fluorescence microscopy

(2018) Yoshiyuki Henning et al.   EXPERIMENTAL EYE RESEARCH

Neuroscience in the third dimension: shedding new light on the brain with tissue clearing

(2017) Robin J. Vigouroux et al.   Molecular Brain

Neural Organization of the Optic Lobe Changes Steadily from Late Embryonic Stage to Adulthood in Cuttlefish Sepia pharaonis

(2017) Yung-Chieh Liu et al.   Frontiers in Physiology

Chemical Principles in Tissue Clearing and Staining Protocols for Whole-Body Cell Profiling

(2016) Kazuki Tainaka et al.   Annual Review of Cell and Developmental Biology

The ciliary marginal zone of the zebrafish retina: clonal and time-lapse analysis of a continuously growing tissue

(2016) Yinan Wan et al.   DEVELOPMENT

Live Imaging of Axolotl Digit Regeneration Reveals Spatiotemporal Choreography of Diverse Connective Tissue Progenitor Pools

(2016) Joshua D. Currie et al.   DEVELOPMENTAL CELL

Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina

(2016) Jaroslav Icha et al.   JOURNAL OF CELL BIOLOGY

Old knowledge and new technologies allow rapid development of model organisms

(2016) Charles E. Cook et al.   MOLECULAR BIOLOGY OF THE CELL

FGF8 and SHH substitute for anterior–posterior tissue interactions to induce limb regeneration

(2016) Eugeniu Nacu et al.   NATURE

Shrinkage-mediated imaging of entire organs and organisms using uDISCO

(2016) Chenchen Pan et al.   NATURE METHODS

Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent

(2016) Meng-Tsen Ke et al.   Cell Reports

Adult axolotls can regenerate original neuronal diversity in response to brain injury

(2016) Ryoji Amamoto et al.   eLife

Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems

(2015) Evan Murray et al.   CELL

Editing plant genomes with CRISPR/Cas9

(2015) Khaoula Belhaj et al.   CURRENT OPINION IN BIOTECHNOLOGY

In praise of other model organisms

(2015) Graham Warren   JOURNAL OF CELL BIOLOGY

Guidelines for the Care and Welfare of Cephalopods in Research –A consensus based on an initiative by CephRes, FELASA and the Boyd Group

(2015) Graziano Fiorito et al.   LABORATORY ANIMALS

The octopus genome and the evolution of cephalopod neural and morphological novelties

(2015) Caroline B. Albertin et al.   NATURE

High-throughput spatial mapping of single-cell RNA-seq data to tissue of origin

(2015) Kaia Achim et al.   NATURE BIOTECHNOLOGY

ScaleS: an optical clearing palette for biological imaging

(2015) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

(2015) Etsuo A Susaki et al.   Nature Protocols

Emerging from the bottleneck: benefits of the comparative approach to modern neuroscience

(2015) Eliot A. Brenowitz et al.   TRENDS IN NEUROSCIENCES

A versatile clearing agent for multi-modal brain imaging

(2015) Irene Costantini et al.   Scientific Reports

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Biochemistry and biosynthesis of insect pigments

(2014) Gulsaz SHAMIM et al.   EUROPEAN JOURNAL OF ENTOMOLOGY

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Optimized axolotl (Ambystoma mexicanum) husbandry, breeding, metamorphosis, transgenesis and tamoxifen-mediated recombination

(2014) Shahryar Khattak et al.   Nature Protocols

Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution

(2014) Anna F Gilles et al.   EvoDevo

Enhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging

(2013) Jeremy F. P. Ullmann et al.   Brain Structure & Function

ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue

(2013) T. Kuwajima et al.   DEVELOPMENT

Posterior elongation in the annelid Platynereis dumerilii involves stem cells molecularly related to primordial germ cells

(2013) Eve Gazave et al.   DEVELOPMENTAL BIOLOGY

Micro-CT in cephalopod research: Investigating the internal anatomy of a sepiolid squid using a non-destructive technique with special focus on the ganglionic system

(2013) Alexandra Kerbl et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

(2013) Meng-Tsen Ke et al.   NATURE NEUROSCIENCE

Stable transgenesis in the marine annelid Platynereis dumerilii sheds new light on photoreceptor evolution

(2013) B. Backfisch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

There's more to life than rats and flies

(2012) Jessica Bolker   NATURE

Three-dimensional imaging of solvent-cleared organs using 3DISCO

(2012) Ali Ertürk et al.   Nature Protocols

Chemical Clearing and Dehydration of GFP Expressing Mouse Brains

(2012) Klaus Becker et al.   PLoS One

Functional diversity of melanopsins and their global expression in the teleost retina

(2011) Wayne I. L. Davies et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain

(2011) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Unexpected Diversity and Photoperiod Dependence of the Zebrafish Melanopsin System

(2011) Vanessa Matos-Cruz et al.   PLoS One

Hawaiian bobtail squid

(2008) Margaret McFall-Ngai   CURRENT BIOLOGY

The external gills of anuran amphibians: Comparative morphology and ultrastructure

(2008) M. Nokhbatolfoghahai et al.   JOURNAL OF MORPHOLOGY

Nogo–Nogo receptor signalling in PNS axon outgrowth and pathfinding

(2008) Christian Brösamle et al.   MOLECULAR AND CELLULAR NEUROSCIENCE