The N-terminus of RPA large subunit and its spatial position are important for the 5′->3′ resection of DNA double-strand breaks

RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response

(2014) Alexandre Maréchal et al.   CELL RESEARCH

A new structural framework for integrating replication protein A into DNA processing machinery

(2013) Chris A. Brosey et al.   NUCLEIC ACIDS RESEARCH

Replication-Dependent and Transcription-Dependent Mechanisms of DNA Double-Strand Break Induction by the Topoisomerase 2-Targeting Drug Etoposide

(2013) Margaret Tammaro et al.   PLoS One

Structure and conformational change of a replication protein A heterotrimer bound to ssDNA

(2012) J. Fan et al.   GENES & DEVELOPMENT

Analysis of MRE11's function in the 5'->3' processing of DNA double-strand breaks

(2012) S. Liao et al.   NUCLEIC ACIDS RESEARCH

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Replication protein A promotes 5′→3′ end processing during homology-dependent DNA double-strand break repair

(2011) Hong Yan et al.   JOURNAL OF CELL BIOLOGY

Mechanistic analysis of Xenopus EXO1's function in 5'-strand resection at DNA double-strand breaks

(2011) S. Liao et al.   NUCLEIC ACIDS RESEARCH

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae

(2010) Hengyao Niu et al.   NATURE

DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2

(2010) Petr Cejka et al.   NATURE

CtIP Links DNA Double-Strand Break Sensing to Resection

(2009) Zhongsheng You et al.   MOLECULAR CELL

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

Cellular Functions of Human RPA1

(2008) Stuart J. Haring et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling

(2008) X. Xu et al.   MOLECULAR AND CELLULAR BIOLOGY

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE