Review
Materials Science, Multidisciplinary
Muzamil Hussain, Syed Hasan Askari Rizvi, Naseem Abbas, Uzair Sajjad, Muhammad Rizwan Shad, Mohsin Ali Badshah, Asif Iqbal Malik
Summary: Titanium, stainless steel, and CoCrMo alloys are the most widely used biomaterials for orthopedic applications, but various factors can lead to implant failure. Coating is considered an effective method to improve implant material performance, and its impact on metallic implants has been extensively studied.
Article
Engineering, Mechanical
Gang Shen, Jufan Zhang, David Culliton, Ruslan Melentiev, Fengzhou Fang
Summary: Tribological performance plays a crucial role in the lifespan of artificial joints. The relationship between surface roughness and coefficient of friction has been studied under both dry and lubricated conditions. The results show that the friction coefficient does not always decrease with decreasing surface roughness under dry test, but instead exhibits a threshold value. However, under wet test, the coefficient of friction consistently decreases as the surface roughness reduces. Surface texturing technology has been proven effective in improving tribological performance.
FRONTIERS OF MECHANICAL ENGINEERING
(2022)
Article
Pharmacology & Pharmacy
Mariana Barbosa, Pedro M. Alves, Fabiola Costa, Claudia Monteiro, Paula Parreira, Catia Teixeira, Paula Gomes, Maria Cristina L. Martins
Summary: Surface immobilization of antimicrobial peptides is a promising strategy to prevent biofilm formation on biomaterials. This study demonstrates that direct surface immobilization of Dhvar5 peptide using copper-catalyzed azide-alkyne cycloaddition method improves antimicrobial activity of chitosan ultrathin coatings.
Review
Biotechnology & Applied Microbiology
Jin Liang, Xinyue Lu, Xinru Zheng, Yu Ru Li, Xiaoyu Geng, Kexin Sun, Hongxin Cai, Qi Jia, Heng Bo Jiang, Kai Liu
Summary: This review discusses the surface modification of titanium alloys with bioactive glass and their applications in bone restoration. The authors systematically reviewed relevant articles published from 2013 to the present, highlighting the different coating technologies and the biological properties of the materials. Despite the limited research, it is believed that bioactive glass-coated titanium implants have great clinical application prospects.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Materials Science, Multidisciplinary
Deepak Rajendra Unune, Georgina R. Brown, Gwendolen C. Reilly
Summary: This review article discusses the importance of metallic biomaterials in clinical applications and their corrosion and wear resistance on implants. The article presents the properties of metallic biomaterials, the reasons for implant failure, and various surface modification techniques to enhance their corrosion and wear resistance.
Article
Chemistry, Physical
Felipe Cemin, Leonardo Luis Artico, Vanessa Piroli, Jose Andres Yunes, Carlos Alejandro Figueroa, Fernando Alvarez
Summary: This study combines the concept of high-entropy designed materials with metallic glasses to develop a high-entropy metallic glass coating for biomedical applications. The coating exhibits amorphous structure, improved corrosion resistance, and enhanced biocompatibility. These properties make it a promising candidate for use as a biocoating on orthopedic implants.
APPLIED SURFACE SCIENCE
(2022)
Review
Polymer Science
Diego Cuartas-Marulanda, Laura Forero Cardozo, Adriana Restrepo-Osorio, Patricia Fernandez-Morales
Summary: Magnesium alloys have unique properties but degrade easily when in contact with body fluids, hence the need for protective coatings. This review focuses on the application of natural biopolymer coatings and modification techniques on magnesium alloys, and compares them with inorganic coatings in terms of corrosion resistance, cell adhesion, proliferation, and biodegradability.
Article
Materials Science, Multidisciplinary
Furkan Bicer, Sidika Mine Toker
Summary: This study aims to comprehensively understand how cellular response to metallic biomaterial surfaces can be controlled by surface parameter specifics and microstructural modifications. The effects of surface micro-deformation and its patterns on cellular response were investigated, and it was found that optimizing surface roughness, dislocation density, and topographical features can significantly enhance cellular response.
MATERIALS TODAY COMMUNICATIONS
(2023)
Review
Chemistry, Applied
Moushumi Ghosh, Arun Kumar Singh
Summary: Ensuring the freshness and shelf-life of fruits is crucial for their proper utilization, and the development of edible nanocoatings with antimicrobial activities has shown great promise in extending the shelf-life while reducing fruit waste.
PROGRESS IN ORGANIC COATINGS
(2022)
Review
Chemistry, Physical
Sung-ryul Choi, Ji-won Kwon, Kyung-soo Suk, Hak-sun Kim, Seong-hwan Moon, Si-young Park, Byung Ho Lee
Summary: As surgical treatments in orthopedics expand, the development of biomaterials used for these treatments has advanced. Biomaterials have osteobiologic properties and can be classified as natural polymers, synthetic polymers, ceramics, allograft-based substitutes, and metallic implants. This review discusses the fundamental characteristics of metals and biomaterials used in the field, as well as advancements in nanotechnology and 3D-printing technology. A complementary relationship between doctors and biomaterial scientists is likely to be necessary in the future.
Review
Chemistry, Multidisciplinary
Srijan Acharya, Satyam Suwas, Kaushik Chatterjee
Summary: Metallic materials are widely used for implants in the human body, with surface severe plastic deformation techniques emerging as promising methods to enhance their performance without chemical modification. These techniques generate nanocrystals at the surface, improving metrics such as fatigue, wear, corrosion resistance, and biocompatibility.
Article
Chemistry, Physical
Oliwia Kierat, Agata Dudek, Lidia Adamczyk
Summary: This paper focuses on the fabrication of coatings using vinyltrimethoxysilane and the effect of various corrosion media on these coatings. The study found that the investigated coatings can slow down the corrosion process, but titanium undergoes pitting corrosion in a bromide ion medium.
Article
Materials Science, Coatings & Films
Ana Santos-Coquillat, Enrique Martinez-Campos, Hugo Mora Sanchez, Lara Moreno, Raul Arrabal, Marta Mohedano, Alberto Gallardo, Juan Rodriguez-Hernandez, Endzhe Matykina
Summary: This review discusses the state-of-the-art strategies for design and fabrication of smart biomaterials for tissue engineering, focusing on metallic biomaterials with hybrid coatings. It outlines key technologies for designing hybrid smart and multifunctional coatings on metallic cores for bone regeneration implants and cardiovascular stents, and highlights recent progress in incorporating drug-eluting functionality into these materials.
SURFACE & COATINGS TECHNOLOGY
(2021)
Review
Chemistry, Physical
S. Thanka Rajan, A. Arockiarajan
Summary: Amorphous thin film metallic glasses (TFMGs) have generated significant interest for their potential in practical applications and scientific importance in the biomedical field.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Review
Biotechnology & Applied Microbiology
Tim Egghe, Rino Morent, Richard Hoogenboom, Nathalie De Geyter
Summary: Antibacterial coatings are essential for preventing implant-related infections. Plasma polymer and polydopamine-based coatings are the most widely studied and versatile approaches, capable of synthesizing different types of antibacterial films. However, more fundamental research is needed before these coatings can be widely used.
TRENDS IN BIOTECHNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Sara Hanaei, Amirhossein Takian, Reza Majdzadeh, Christopher Ryan Maboloc, Igor Grossmann, Orlando Gomes, Milos Milosevic, Manoj Gupta, Alireza A. Shamshirsaz, Amine Harbi, Amer M. Burhan, Lucina Q. Uddin, Arutha Kulasinghe, Chi-Ming Lam, Seeram Ramakrishna, Abass Alavi, Jan L. Nouwen, Tommaso Dorigo, Michael Schreiber, Ajith Abraham, Natalya Shelkovaya, Wojtek Krysztofiak, Majid Ebrahimi Warkiani, Frank Sellke, Shuji Ogino, Francisco J. Barba, Serge Brand, Clara Vasconcelos, Deepak B. Salunke, Nima Rezaei
Summary: The COVID-19 pandemic has had a significant impact on human life, leading to the postponement, cancellation, or virtualization of activities that require gatherings. While virtual settings offer increased inclusivity and accessibility and reduce carbon emissions, they cannot fully replace in-person scientific events. In-person meetings allow for socialization, collaboration, and idea sharing, providing novel opportunities. A hybrid model that combines in-person and virtual components may be a solution, allowing participants to choose their preferred mode of participation.
DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS
(2022)
Review
Food Science & Technology
Prasoon Kumar, Rajeshwari Sinha, Pratyoosh Shukla
Summary: This article discusses the crucial role of AI-assisted synthetic biology in modulating probiotics and improving human gut microbiome health. AI techniques help in understanding the genomic data of the gut microbiome and provide opportunities and challenges for the development of synthetic biology.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Anatomy & Morphology
Sairish Malik, Subramanian Sundarrajan, Tanveer Hussain, Ahsan Nazir, Seeram Ramakrishna
Summary: Research on nanomaterials has led to the exploitation of their potential applications, with electrospinning being particularly noteworthy for its ability to synthesize novel nanostructures. Among these, polymers, especially block copolymers, are extensively studied due to their unique properties and behavior when varying composition ratio and molecular weight, making them suitable for a wide range of applications.
CELLS TISSUES ORGANS
(2022)
Article
Biotechnology & Applied Microbiology
Hadi Rouhani, Fatola Farhadi, Mahsa Akbari Kenari, Seeram Ramakrishna
Summary: By optimizing the temperature range for clay treatment, the study achieved a longer service life for the clay and introduced a new process arrangement that significantly reduced operational costs in industrial production.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Heng-Shu Guan, Wei-Zhi Song, Lin-Peng Huang, Zhong Liu, Jun Zhang, Seeram Ramakrishna, Yun-Ze Long
Summary: Biofuel cell is a technology that converts renewable energy into electricity using biological enzymes. Researchers have successfully developed a biofuel cell based on a polyaniline/thermoplastic polyurethane fiber membrane, which can stably output voltage in simulated blood, showing potential applications in implantable devices and blood glucose monitoring.
Review
Chemistry, Multidisciplinary
Ruchira Chakraborty, Abhijeet Govind Anoop, Abhay Thakur, Girish Chandra Mohanta, Prasoon Kumar
Summary: 3D printing is an effective scaffold fabrication technique that has the potential to revolutionize tissue engineering. While solid scaffolds developed through 3D printing are highly sought after, their limited surface and bulk properties hinder their applications in tissue integration and other areas. Efforts have been made to modify these properties, resulting in improved adoption of 3D-printed solid scaffolds in the healthcare industry. However, the in vivo implant applications of these scaffolds/devices are still under development, requiring attention to their functionality and properties.
Review
Chemistry, Multidisciplinary
Pragyan Ray, Ruchira Chakraborty, Oindrila Banik, Earu Banoth, Prasoon Kumar
Summary: Membrane technology plays a crucial role in cutting-edge innovations in the biomedical field, particularly in surface engineering for enhanced membrane longevity, efficient separation, and better throughput. Various chemical-based surface modifications and physical micro/nanotopographies are employed to improve cellular attachment, directional migration, and communication, as well as enhance diffusional transport of nutrients, gases, and waste across the membrane. These modifications not only enhance functional efficiency but also address fouling issues, biofilm formation, and infection incidences. This comprehensive review discusses different types of membranes, their fabrication and surface modifications, antifouling/antibacterial strategies, and their applications in tissue engineering, bioseparation, extracorporeal membrane devices, wound healing, and more.
Article
Metallurgy & Metallurgical Engineering
Rohit Parkale, Priyanka Pulugu, Prasoon Kumar
Summary: Commercial cotton gauze bandages are modified to have anti-microbial properties and the capability of localised drug delivery in order to minimize pain and post-dressing infections at wound sites. The modification involves layering a biodegradable, drug-loaded nanofibrous mat on top of a commercial cotton bandage with a chitosan coating and zinc oxide nanoparticles for antibacterial and UV protection purposes. This study suggests that nanomaterials on cotton gauze bandages can be an effective alternative for wound dressing applications.
INTERNATIONAL JOURNAL OF MATERIALS RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Dilip Kumar Chandra, Awanish Kumar, Chinmaya Mahapatra
Summary: This article reports the rapid production method of cerium oxide microtubes (CeO2-MT) and their cytocompatibility with C2C12 cells for the first time. The results show that these microtubes have high antioxidant activity and can be used as novel biomaterials for potential muscle tissue regeneration.
EMERGENT MATERIALS
(2023)
Article
Engineering, Biomedical
Kamasani Aarya Sree, Anusha Yagnik, Prerna Komal Chordiya, Kaushik Choudhury, Prasoon Kumar
Summary: The key to highly efficient microfluidic devices and functional tissues lies in mimicking the vasculature and hierarchical structures found in nature. These structures are crucial for heat and mass transfer, which are essential for supporting life functions. However, replicating these structures at micro and nanoscale has been a challenge in the fabrication of lab-on-chip devices and functional tissues. This review provides an overview of existing techniques used for creating nature-inspired vasculature in the lab, and also highlights the prime applications of these techniques.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Chemistry, Physical
T. Yadav, A. K. Vishwkarma, M. Mandal, I. Karmakar, A. Pathak, G. Brahmachari, P. K. Tripathi, A. K. Maddheshiya, N. P. Yadav, C. Mahapatra
Summary: The structural and spectroscopic analysis of a warfarin derivative was performed, and low-lying energy conformations of this compound were found through one-dimensional potential energy scanning. The potential energy distributions and vibrational spectra of the most stable conformer were calculated and compared with experimental results. This investigation provides crucial information for further studies on similar compounds.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Environmental Sciences
Dilip Kumar Chandra, Awanish Kumar, Chinmaya Mahapatra
Summary: This study presents a simple approach for producing high-performance biodegradable plastic from plant-based resources using in situ lignin regeneration. The cellulose-chitosan slurry is formed by the deconstruction of leaves collected from plants, and cellulose bioplastic materials are produced by hydrogen bonding. The fabricated bioplastics exhibit excellent mechanical properties, water stability, and thermal stability. Additionally, lignocellulosic bioplastic has a lower environmental impact due to its simple recycling or secure biodegradability.
WASTE AND BIOMASS VALORIZATION
(2023)
Review
Materials Science, Multidisciplinary
Dilip Kumar Chandra, Rui L. Reis, Subhas C. Kundu, Awanish Kumar, Chinmaya Mahapatra
Summary: Carbon nanotubes (CNTs) offer significant potential in antifungal drug delivery. Their unique physicochemical properties and the development of functionalized CNTs and CNT-based hybrid materials (CNT-HMs) enable precise drug delivery, bio-barrier penetration, controlled release, and improved antifungal efficacy against fungal cells. This review examines CNTs and CNT-HMs in antifungal drug delivery, covering functionalization, drug loading, efficacy, and toxicity mitigation.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Chemistry, Analytical
Xue Pan, Lu Bai, Chengcheng Pan, Zhicheng Liu, Seeram Ramakrishna
Summary: This review discusses the fabrication methods and applications of SERS substrates based on electrospun nanofibers, and highlights the challenges and prospects.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Review
Engineering, Biomedical
Masoud Sarraf, Erfan Rezvani Ghomi, Saeid Alipour, Seeram Ramakrishna, Nazatul Liana Sukiman
Summary: Commercially pure titanium and titanium alloys are widely used in biomedical applications due to their excellent mechanical properties, corrosion resistance, biocompatibility, and antibacterial properties. Future research will focus on advanced manufacturing technologies, effects of alloying elements on biocompatibility, and the role of titanium in regenerative and nanomedicine applications.
BIO-DESIGN AND MANUFACTURING
(2022)
