ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure

Pulmonary group 2 innate lymphoid cells: surprises and challenges

(2019) Malcolm R. Starkey et al.   Mucosal Immunology

Group 2 Innate Lymphoid Cells in Human Respiratory Disorders

(2019) Esmee K. van der Ploeg et al.   Journal of Innate Immunity

Expression of c‐Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells

(2019) Thomas Hochdörfer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

(2019) Anja Schulz-Kuhnt et al.   Jove-Journal of Visualized Experiments

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

(2019) Amanda Ardain et al.   NATURE

c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

(2019) Jochem H. Bernink et al.   NATURE IMMUNOLOGY

IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation

(2019) Korneliusz Golebski et al.   Nature Communications

Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans

(2019) Franz Puttur et al.   Science Immunology

A CCL1/CCR8-dependent feed-forward mechanism drives ILC2 functions in type 2–mediated inflammation

(2019) Lisa Knipfer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

(2018) Timotheus Y.F. Halim et al.   IMMUNITY

Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis

(2018) Alina Soare et al.   JOURNAL OF IMMUNOLOGY

Inflammation in cystic fibrosis: An update

(2018) Erica A. Roesch et al.   PEDIATRIC PULMONOLOGY

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

(2018) Yuefeng Huang et al.   SCIENCE

ILC2s in infectious diseases and organ-specific fibrosis

(2018) Markus Kindermann et al.   Seminars in Immunopathology

Group 2 Innate Lymphoid Cells in Pulmonary Immunity and Tissue Homeostasis

(2018) Barbara C. Mindt et al.   Frontiers in Immunology

Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes

(2018) Ilkka S. Junttila   Frontiers in Immunology

The CC chemokines CCL8, CCL13 and CCL20 are local inflammatory biomarkers of HLA-B27-associated uveitis

(2018) Ahmed M. Abu El-Asrar et al.   ACTA OPHTHALMOLOGICA

Innate lymphoid cells in organ fibrosis

(2018) Yohei Mikami et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease

(2018) Chantal Donovan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tissue signals imprint ILC2 identity with anticipatory function

(2018) Roberto R. Ricardo-Gonzalez et al.   NATURE IMMUNOLOGY

ILC-poiesis: Ensuring tissue ILC differentiation at the right place and time

(2018) Ai Ing Lim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate lymphoid cells in lung infection and immunity

(2018) Christina Stehle et al.   IMMUNOLOGICAL REVIEWS

Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation

(2018) Jovana Maric et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Type VI collagen promotes lung epithelial cell spreading and wound-closure

(2018) Jared A. Mereness et al.   PLoS One

ILC2s — resident lymphocytes pre-adapted to a specific tissue or migratory effectors that adapt to where they move?

(2018) Ronald N Germain et al.   CURRENT OPINION IN IMMUNOLOGY

IL-33: biological properties, functions, and roles in airway disease

(2017) Li Yin Drake et al.   IMMUNOLOGICAL REVIEWS

Group 2 innate lymphoid cells are recruited to the nasal mucosa in patients with aspirin-exacerbated respiratory disease

(2017) Jacqueline J. Eastman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease

(2017) Agnes Gwela et al.   Journal of Crohns & Colitis

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis

(2017) Debomita Chakraborty et al.   Nature Communications

A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis

(2017) Silvia Moretti et al.   Nature Communications

Testosterone Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation

(2017) Jacqueline-Yvonne Cephus et al.   Cell Reports

Bronchiectasis: Current Concepts in Pathogenesis, Immunology, and Microbiology

(2016) Rosemary J. Boyton et al.   Annual Review of Pathology-Mechanisms of Disease

Innate and Adaptive Immunity in Cystic Fibrosis

(2016) Emanuela M. Bruscia et al.   CLINICS IN CHEST MEDICINE

Innate lymphoid cells in asthma: Will they take your breath away?

(2016) Hye Young Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia

(2016) Steven G. Smith et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Risk of asthma in heterozygous carriers for cystic fibrosis: A meta-analysis

(2016) Anne Orholm Nielsen et al.   Journal of Cystic Fibrosis

CD4+Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis

(2016) Florence Roan et al.   JOURNAL OF IMMUNOLOGY

Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

(2016) Anika Klingberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection

(2016) V S Pelly et al.   Mucosal Immunology

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

(2016) Suzanne M Bal et al.   NATURE IMMUNOLOGY

Update of literature from cystic fibrosis registries 2012-2015. Part 6: Epidemiology, nutrition and complications

(2016) Donatello Salvatore et al.   PEDIATRIC PULMONOLOGY

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

(2016) Anjali Y. Bhagirath et al.   BMC Pulmonary Medicine

Diagnosis and early life risk factors for bronchiectasis in cystic fibrosis: a review

(2016) Peter D. Sly et al.   Expert Review of Respiratory Medicine

Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung

(2016) Katrien C. De Grove et al.   PLoS One

Type 2 innate lymphoid cell counts are increased in patients with systemic sclerosis and correlate with the extent of fibrosis

(2015) Thomas Wohlfahrt et al.   ANNALS OF THE RHEUMATIC DISEASES

Forced oscillations and respiratory system modeling in adults with cystic fibrosis

(2015) Adma N Lima et al.   Biomedical Engineering Online

Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis

(2015) Luke W. Garratt et al.   EUROPEAN RESPIRATORY JOURNAL

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers

(2015) Hideaki Morita et al.   IMMUNITY

The prostaglandin D2 receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung

(2015) E D Tait Wojno et al.   Mucosal Immunology

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs

(2015) G. Gasteiger et al.   SCIENCE

Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin

(2014) J. Mjösberg et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Differential expression of IL-33 and HMGB1 in the lungs of stable cystic fibrosis patients

(2014) K. Tiringer et al.   EUROPEAN RESPIRATORY JOURNAL

Development, Differentiation, and Diversity of Innate Lymphoid Cells

(2014) Andreas Diefenbach et al.   IMMUNITY

Enhanced innate type 2 immune response in peripheral blood from patients with asthma

(2014) Kathleen R. Bartemes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells

(2014) Luzheng Xue et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CCR6 Regulates the Migration of Inflammatory and Regulatory T Cells

(2014) T. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

An in vitro model of innate lymphoid cell function and differentiation

(2014) D SJ Allan et al.   Mucosal Immunology

A Th17- and Th2-skewed Cytokine Profile in Cystic Fibrosis Lungs Represents a Potential Risk Factor forPseudomonas aeruginosaInfection

(2013) Kerstin Tiringer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SnapShot: Innate Lymphoid Cells

(2013) Gregory F. Sonnenberg et al.   IMMUNITY

Annexin A2 mediates secretion of collagen VI, pulmonary elasticity and apoptosis of bronchial epithelial cells

(2013) MaryAnn Dassah et al.   JOURNAL OF CELL SCIENCE

Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4

(2013) Zamaneh Mikhak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

(2013) Maryam Salimi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis

(2013) Peter D. Sly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease

(2013) William T. Harris et al.   PLoS One

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis

(2013) E. Hams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-17 in lung disease: friend or foe?

(2013) Hui-Leng Tan et al.   THORAX

Immune Responses in Cystic Fibrosis

(2012) Dmitry Ratner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

(2012) Ashish Bhattacharjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

IL-33 is expressed in epithelia from patients with cystic fibrosis and potentiates neutrophil recruitment

(2012) Lucie Roussel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cystic fibrosis: a mucosal immunodeficiency syndrome

(2012) Taylor Sitarik Cohen et al.   NATURE MEDICINE

Reticular basement membrane in asthma and COPD: Similar thickness, yet different composition

(2012) NH ten Hacken   International Journal of Chronic Obstructive Pulmonary Disease

The Th17 Pathway in Cystic Fibrosis Lung Disease

(2011) Hui-Leng Tan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Collagen VI is a basement membrane component that regulates epithelial cell–fibronectin interactions

(2011) Jean-François Groulx et al.   MATRIX BIOLOGY

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease

(2010) M. Brodlie et al.   EUROPEAN RESPIRATORY JOURNAL