Size-Dependent Pulmonary Impact of Thin Graphene Oxide Sheets in Mice: Toward Safe-by-Design

Granulomatous lung inflammation is nanoparticle type-dependent

(2018) Yves Pacheco et al.   EXPERIMENTAL LUNG RESEARCH

Short-term inhalation study of graphene oxide nanoplates

(2018) Young Hun Kim et al.   Nanotoxicology

Targeting the NLRP3 inflammasome in inflammatory diseases

(2018) Matthew S. J. Mangan et al.   NATURE REVIEWS DRUG DISCOVERY

A blueprint for the synthesis and characterisation of thin graphene oxide with controlled lateral dimensions for biomedicine

(2018) Artur Filipe Rodrigues et al.   2D Materials

Graphene Oxide Elicits Membrane Lipid Changes and Neutrophil Extracellular Trap Formation

(2018) Sourav P. Mukherjee et al.   Chem

The Worldwide Graphene Flake Production

(2018) Alan P. Kauling et al.   ADVANCED MATERIALS

Immunological impact of graphene oxide sheets in the abdominal cavity is governed by surface reactivity

(2018) Artur Filipe Rodrigues et al.   ARCHIVES OF TOXICOLOGY

Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells

(2018) Yanyan Liao et al.   Scientific Reports

Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment

(2018) Bengt Fadeel et al.   ACS Nano

Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles

(2017) Pedro M. Costa et al.   JOURNAL OF APPLIED TOXICOLOGY

Cytokine Profiling of Primary Human Macrophages Exposed to Endotoxin-Free Graphene Oxide: Size-Independent NLRP3 Inflammasome Activation

(2017) Sourav P. Mukherjee et al.   Advanced Healthcare Materials

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

(2017) Sourav P. Mukherjee et al.   Nanoscale

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide

(2017) Stefan Bengtson et al.   PLoS One

The Effects of Extensive Glomerular Filtration of Thin Graphene Oxide Sheets on Kidney Physiology

(2016) Dhifaf A. Jasim et al.   ACS Nano

dupRadar: a Bioconductor package for the assessment of PCR artifacts in RNA-Seq data

(2016) Sergi Sayols et al.   BMC BIOINFORMATICS

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

(2016) Laura Herrtwich et al.   CELL

Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection

(2016) Mark R. Cronan et al.   IMMUNITY

Pulmonary persistence of graphene nanoplatelets may disturb physiological and immunological homeostasis

(2016) Eun-Jung Park et al.   JOURNAL OF APPLIED TOXICOLOGY

28-Day inhalation toxicity of graphene nanoplatelets in Sprague-Dawley rats

(2016) Jin Kwon Kim et al.   Nanotoxicology

Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals

(2015) Juan Ma et al.   ACS Nano

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

5-Day repeated inhalation and 28-day post-exposure study of graphene

(2015) Jae Hoon Shin et al.   Nanotoxicology

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Evaluation of pulmonary and systemic toxicity following lung exposure to graphite nanoplates: a member of the graphene-based nanomaterial family

(2015) Jenny R. Roberts et al.   Particle and Fibre Toxicology

Dispersibility-Dependent Biodegradation of Graphene Oxide by Myeloperoxidase

(2015) Rajendra Kurapati et al.   Small

Graphene Oxide Attenuates Th2-Type Immune Responses, but Augments Airway Remodeling and Hyperresponsiveness in a Murine Model of Asthma

(2014) Michael R. Shurin et al.   ACS Nano

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

(2014) Neus Feliu et al.   ACS Nano

Lung Macrophages “Digest” Carbon Nanotubes Using a Superoxide/Peroxynitrite Oxidative Pathway

(2014) Valerian E. Kagan et al.   ACS Nano

Classification Framework for Graphene-Based Materials

(2014) Peter Wick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toxic response of graphene nanoplatelets in vivo and in vitro

(2014) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes

(2014) Yann Grosse et al.   LANCET ONCOLOGY

Challenges and opportunities in graphene commercialization

(2014) Amaia Zurutuza et al.   Nature Nanotechnology

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2014) Carol Kilkenny et al.   Animals

Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages

(2013) Guangbo Qu et al.   ACS Nano

Genotoxicity and carcinogenicity risk of carbon nanotubes

(2013) Shinya Toyokuni   ADVANCED DRUG DELIVERY REVIEWS

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

All in the graphene family – A recommended nomenclature for two-dimensional carbon materials

(2013) Alberto Bianco et al.   CARBON

Minimal oxidation and inflammogenicity of pristine graphene with residence in the lung

(2013) Anja Schinwald et al.   Nanotoxicology

Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

(2013) Lan Ma-Hock et al.   Particle and Fibre Toxicology

Biodistribution and pulmonary toxicity of intratracheally instilled graphene oxide in mice

(2013) Bo Li et al.   NPG Asia Materials

Confocal Raman Imaging Study Showing Macrophage Mediated Biodegradation of Graphene In Vivo

(2013) Chundayil Madathil Girish et al.   Advanced Healthcare Materials

Occupational Nanosafety Considerations for Carbon Nanotubes and Carbon Nanofibers

(2012) Vincent Castranova et al.   ACCOUNTS OF CHEMICAL RESEARCH

Safety Considerations for Graphene: Lessons Learnt from Carbon Nanotubes

(2012) Cyrill Bussy et al.   ACCOUNTS OF CHEMICAL RESEARCH

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A roadmap for graphene

(2012) K. S. Novoselov et al.   NATURE

Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

(2012) Anna A. Shvedova et al.   PLoS One

Evidence for local dendritic cell activation in pulmonary sarcoidosis

(2012) Bregje Berge et al.   RESPIRATORY RESEARCH

Graphene-Based Nanoplatelets: A New Risk to the Respiratory System as a Consequence of Their Unusual Aerodynamic Properties

(2011) Anja Schinwald et al.   ACS Nano

Novel Murine Model of Chronic Granulomatous Lung Inflammation Elicited by Carbon Nanotubes

(2011) Isham Huizar et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Type I Interferon Signaling Contributes to Chronic Inflammation in a Murine Model of Silicosis

(2010) Giulia Giordano et al.   TOXICOLOGICAL SCIENCES

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

(2009) Dale W. Porter et al.   TOXICOLOGY

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY