Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies

β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells

(2019) Shiori Aono et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Broad regulation of gene isoform expression by Wnt signaling in cancer

(2019) Muhammad Idris et al.   RNA

NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor

(2019) Laura Novellasdemunt et al.   EMBO JOURNAL

Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?

(2018) RG Morgan et al.   BRITISH JOURNAL OF CANCER

Down-regulation of lncTCF7 inhibits cell migration and invasion in colorectal cancer via inhibiting TCF7 expression

(2018) Baihe Wu et al.   Human Cell

TCF/LEF dependent and independent transcriptional regulation of Wnt/β‐catenin target genes

(2018) Nikolaos Doumpas et al.   EMBO JOURNAL

Differential expression of LEF1/TCFs family members in colonic carcinogenesis

(2017) Wenxiao Han et al.   MOLECULAR CARCINOGENESIS

Visualization and targeting of LGR5+ human colon cancer stem cells

(2017) Mariko Shimokawa et al.   NATURE

The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells

(2017) Daisuke Shiokawa et al.   Cell Reports

Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing

(2016) Oskar Schnappauf et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

(2016) Catherine E. Bond et al.   Oncotarget

The Role of the C-Clamp in Wnt-Related Colorectal Cancers

(2016) Aditi Ravindranath et al.   Cancers

Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer

(2016) Huai-Xiang Hao et al.   Cancers

Frizzled7: A Promising Achilles’ Heel for Targeting the Wnt Receptor Complex to Treat Cancer

(2016) Toby Phesse et al.   Cancers

TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3

(2016) Matthew Murphy et al.   Scientific Reports

Dickkopf-1 expression is down-regulated during the colorectal adenoma-carcinoma sequence and correlates with reduced microvessel density and VEGF expression

(2015) Zhiyong Liu et al.   HISTOPATHOLOGY

S100P, a calcium-binding protein, is preferentially associated with the growth of polypoid tumors in colorectal cancer

(2015) JY-MING CHIANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression

(2015) E Sánchez-Tilló et al.   ONCOGENE

Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5+ Stem Cells

(2015) Dustin J. Flanagan et al.   Stem Cell Reports

Conducting Meta-Analyses inRwith themetaforPackage

(2015) Wolfgang Viechtbauer   Journal of Statistical Software

Large differences in global transcriptional regulatory programs of normal and tumor colon cells

(2014) David Cordero et al.   BMC CANCER

A nineteen gene-based risk score classifier predicts prognosis of colorectal cancer patients

(2014) Seon-Kyu Kim et al.   Molecular Oncology

RNF43 is frequently mutated in colorectal and endometrial cancers

(2014) Marios Giannakis et al.   NATURE GENETICS

The TCF C-clamp DNA binding domain expands the Wnt transcriptome via alternative target recognition

(2014) Nate P. Hoverter et al.   NUCLEIC ACIDS RESEARCH

Increased LEF1 Expression and Decreased Notch2 Expression Are Strong Predictors of Poor Outcomes in Colorectal Cancer Patients

(2013) Wen-Juan Wang et al.   DISEASE MARKERS

High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications

(2013) Christina Röhr et al.   PLoS One

Knockdown of Lymphoid Enhancer factor 1 Inhibits Colon Cancer Progression In Vitro and In Vivo

(2013) Wen-Juan Wang et al.   PLoS One

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness

(2012) Ester Sánchez-Tilló et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cell-Context Dependent TCF/LEF Expression and Function: Alternative Tales of Repression, De-Repression and Activation Potentials

(2012) Catherine D. Mao et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

(2011) T. Hinoue et al.   GENOME RESEARCH

HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression

(2011) Y Li et al.   ONCOGENE

Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas

(2010) Jochen Gaedcke et al.   GENES CHROMOSOMES & CANCER

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

(2009) Hoang Nguyen et al.   NATURE GENETICS

A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer

(2009) R Najdi et al.   ONCOGENE

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in Colorectal Cancer and Is a Therapeutic Target of Histone Modifications

(2008) Xia Jiang et al.   CANCER CELL

The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression

(2008) Elizabeth Vincan et al.   CLINICAL & EXPERIMENTAL METASTASIS

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE