Pathways Connecting Late-Life Depression and Dementia

Sex-Specific Associations Between Depressive Symptoms and Risk for Subsequent Dementia

(2020) Kathrin Heser et al.   JOURNAL OF ALZHEIMERS DISEASE

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

Sex differences in vulnerability and resilience to stress across the lifespan

(2019) Georgia E. Hodes et al.   BIOLOGICAL PSYCHIATRY

The role of inflammation and the gut microbiome in depression and anxiety

(2019) Jason M. Peirce et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer’s Disease

(2019) David Henley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease

(2019) Michael F. Egan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telomere Shortening in the Alzheimer’s Disease Neuroimaging Initiative Cohort

(2019) Kelly N.H. Nudelman et al.   JOURNAL OF ALZHEIMERS DISEASE

Time to test antibacterial therapy in Alzheimer’s disease

(2019) Francesco Panza et al.   BRAIN

Epigenetics and Depression: An Update

(2019) Eugene Lin et al.   Psychiatry Investigation

Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer’s disease

(2019) Michael F. Egan et al.   Alzheimers Research & Therapy

Mechanisms and treatment of late-life depression

(2019) George S. Alexopoulos   Translational Psychiatry

Do anti-amyloid-β drugs affect neuropsychiatric status in Alzheimer’s disease patients?

(2019) Francesco Panza et al.   AGEING RESEARCH REVIEWS

A specific group of patients with diagnostic conversion from depression to bipolar disorder and finally to dementia as a mental GSK‐3 disease: a hypothesis

(2019) Takeshi Terao et al.   BIPOLAR DISORDERS

Gut microbiota–brain axis in depression: The role of neuroinflammation

(2019) Anelise S. Carlessi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The stability of neuropsychiatric subsyndromes in Alzheimer's disease

(2018) Michael H. Connors et al.   Alzheimers & Dementia

Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults

(2018) Nancy J. Donovan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Epigenetic regulatory modifications in genetic and sporadic frontotemporal dementia

(2018) Chiara Fenoglio et al.   Expert Review of Neurotherapeutics

Course of neuropsychiatric symptoms in dementia: 5-year longitudinal study

(2018) Audun Osland Vik-Mo et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis

(2018) Andrea Cipriani et al.   LANCET

Sex differences in Alzheimer disease — the gateway to precision medicine

(2018) Maria Teresa Ferretti et al.   Nature Reviews Neurology

Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target

(2018) Filippo Caraci et al.   PHARMACOLOGICAL RESEARCH

Molecular imaging of neuroinflammation in Alzheimer's disease and mild cognitive impairment

(2018) Dunja Knezevic et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Epigenetic regulatory modifications in genetic and sporadic frontotemporal dementia

(2018) Chiara Fenoglio et al.   Expert Review of Neurotherapeutics

The Molecular Intersection Between Senescence and Major Depression in the Elderly

(2018) Breno S. Diniz   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Early Life Stress and Epigenetics in Late-onset Alzheimer’s Dementia: A Systematic Review

(2018) Erwin Lemche   CURRENT GENOMICS

Depression History, Depressive Symptoms, and Incident Dementia: The 3C Study

(2018) Hermine Lenoir et al.   JOURNAL OF ALZHEIMERS DISEASE

Emerging role of amyloid beta in stress response: Implication for depression and diabetes

(2017) Maria Grazia Morgese et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Increased hippocampal tail volume predicts depression status and remission to anti-depressant medications in major depression

(2017) J J Maller et al.   MOLECULAR PSYCHIATRY

Antidepressant drugs for beta amyloid-induced depression: A new standpoint?

(2017) Stefania Schiavone et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increase of BDNF Serum Concentration in Lithium Treated Patients with Early Alzheimer's Disease

(2017) Thomas Leyhe et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-β Peptides in Plasma and Cognitive Decline After 1 Year Follow-Up in Alzheimer's Disease Patients

(2017) Christoph Laske et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid Hypothesis: Is There a Role for Antiamyloid Treatment in Late-Life Depression?

(2016) Nahla Mahgoub et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Longitudinal course of behavioural and psychological symptoms of dementia: systematic review

(2016) Rianne M. van der Linde et al.   BRITISH JOURNAL OF PSYCHIATRY

Depression as a risk factor for Alzheimer’s disease: Genes, steroids, cytokines and neurogenesis – What do we need to know?

(2016) Joe Herbert et al.   FRONTIERS IN NEUROENDOCRINOLOGY

High amyloid-β deposition related to depressive symptoms in older individuals with normal cognition: a pilot study

(2016) Fumihiko Yasuno et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Hippocampal subfield analysis in medication-naïve female patients with major depressive disorder

(2016) Kyu-Man Han et al.   JOURNAL OF AFFECTIVE DISORDERS

Epigenetics of dementia: understanding the disease as a transformation rather than a state

(2016) Bryan Maloney et al.   LANCET NEUROLOGY

Late-life depression is not associated with dementia-related pathology.

(2016) Robert S. Wilson et al.   NEUROPSYCHOLOGY

Role of neuro-immunological factors in the pathophysiology of mood disorders

(2016) Anindya Bhattacharya et al.   PSYCHOPHARMACOLOGY

From cellular senescence to Alzheimer’s disease: The role of telomere shortening

(2015) Virginia Boccardi et al.   AGEING RESEARCH REVIEWS

Illness Progression, Recent Stress, and Morphometry of Hippocampal Subfields and Medial Prefrontal Cortex in Major Depression

(2015) Michael T. Treadway et al.   BIOLOGICAL PSYCHIATRY

Lithium treatment and risk for dementia in adults with bipolar disorder: Population-based cohort study

(2015) Tobias Gerhard et al.   BRITISH JOURNAL OF PSYCHIATRY

Gender differences in risk factors for transition from mild cognitive impairment to Alzheimer’s disease: A CREDOS study

(2015) Sangha Kim et al.   COMPREHENSIVE PSYCHIATRY

Dentate gyrus volume and memory performance in major depressive disorder

(2015) Scott Travis et al.   JOURNAL OF AFFECTIVE DISORDERS

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Margaret McCartney: The “breakthrough” drug that’s not been shown to help in Alzheimer’s disease

(2015) Margaret McCartney   BMJ-British Medical Journal

Margaret McCartney: The “breakthrough” drug that’s not been shown to help in Alzheimer’s disease

(2015) Margaret McCartney   BMJ-British Medical Journal

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

(2015) Elaine Setiawan et al.   JAMA Psychiatry

Soluble beta amyloid evokes alteration in brain norepinephrine levels: role of nitric oxide and interleukin-1

(2015) Maria G. Morgese et al.   Frontiers in Neuroscience

Depressive symptoms predict incident dementia during short- but not long-term follow-up period

(2014) Saira Saeed Mirza et al.   Alzheimers & Dementia

Association between Glucocorticoid Receptor Methylation and Hippocampal Subfields in Major Depressive Disorder

(2014) Kyoung-Sae Na et al.   PLoS One

Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls–preliminary findings

(2014) Daniel Lindqvist et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Epigenetic Mechanisms of Depression

(2014) Eric J. Nestler   JAMA Psychiatry

Structural Changes in Hippocampal Subfields in Major Depressive Disorder: A High-Field Magnetic Resonance Imaging Study

(2013) Yushan Huang et al.   BIOLOGICAL PSYCHIATRY

Incidence of dementia: evidence for an effect modification by gender. The ILSA Study

(2013) Marianna Noale et al.   INTERNATIONAL PSYCHOGERIATRICS

Brain-Derived Neurotrophic Factor Serum Concentrations in Acute Depressive Patients Increase During Lithium Augmentation of Antidepressants

(2013) Roland Ricken et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

BDNF: an indicator of insomnia?

(2013) M Giese et al.   MOLECULAR PSYCHIATRY

Changes of Serum Concentrations of Brain-Derived Neurotrophic Factor (BDNF) during Treatment with Venlafaxine and Mirtazapine: Role of Medication and Response to Treatment

(2012) M. Deuschle et al.   PHARMACOPSYCHIATRY

Cross-national epidemiology of DSM-IV major depressive episode

(2011) Evelyn Bromet et al.   BMC Medicine

Neuropathological correlates of late-life depression in older people

(2011) Christos Tsopelas et al.   BRITISH JOURNAL OF PSYCHIATRY

Genetic polymorphisms of cytochrome P450 enzymes and antidepressant metabolism

(2011) Stefano Porcelli et al.   Expert Opinion on Drug Metabolism & Toxicology

Reduced Brain-Derived Neurotrophic Factor Serum Concentrations in Acute Schizophrenic Patients Increase During Antipsychotic Treatment

(2011) Ah Hyun Lee et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Plasma Amyloid Beta-42 Independently Predicts Both Late-Onset Depression and Alzheimer Disease

(2010) Imrich Blasko et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients

(2010) Christoph Laske et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Subregional hippocampal deformations in major depressive disorder

(2010) James Cole et al.   JOURNAL OF AFFECTIVE DISORDERS

Predictive Value of Platelet Activation for the Rate of Cognitive Decline in Alzheimer's Disease Patients

(2010) Konstantinos Stellos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Altered T2* relaxation time of the hippocampus in major depressive disorder: Implications of ultra-high field magnetic resonance imaging

(2010) Zang-Hee Cho et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Late life depression: a comparison of risk factors and symptoms according to age of onset in community dwelling older adults

(2009) Damien Gallagher et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Wake and sleep EEG provide biomarkers in depression

(2009) Axel Steiger et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Increased Neurofibrillary Tangles in Patients With Alzheimer Disease With Comorbid Depression

(2008) Michael A. Rapp et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Lithium Treatment and Risk of Dementia

(2008) Lars Vedel Kessing et al.   ARCHIVES OF GENERAL PSYCHIATRY

Higher BDNF concentrations in the hippocampus and cortex of an aggressive mouse strain

(2008) U LANG et al.   BEHAVIOURAL BRAIN RESEARCH

Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

(2008) Srijan Sen et al.   BIOLOGICAL PSYCHIATRY

Severity of depression and risk for subsequent dementia: cohort studies in China and the UK

(2008) Ruoling Chen et al.   BRITISH JOURNAL OF PSYCHIATRY

Inverse association of cortisol serum levels with T-tau, P-tau 181 and P-tau 231 peptide levels and T-tau/Aβ 1–42 ratios in CSF in patients with mild Alzheimer’s disease dementia

(2008) Christoph Laske et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

(2008) André Russowsky Brunoni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Risk profiles for mild cognitive impairment and progression to dementia are gender specific

(2008) S Artero et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

(2008) Raj N Kalaria et al.   LANCET NEUROLOGY

Serum Concentrations of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Depressed Patients before and after Antidepressant Treatment

(2008) R. Hellweg et al.   PHARMACOPSYCHIATRY

Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study

(2007) Martin Steinberg et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY