Genetic polymorphisms of cytochrome P450 enzymes and antidepressant metabolism

Effects of Cigarette Smoking and Cytochrome P450 2D6 Genotype on Fluvoxamine Concentration in Plasma of Japanese Patients

(2010) Yasuhiro Katoh et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Changes in the QTc interval after administration of flecainide acetate, with and without coadministered Paroxetine, in Relation to Cytochrome P450 2D6 Genotype: Data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects

(2010) Kyoung Soo Lim et al.   CLINICAL THERAPEUTICS

Genetic Variation in Metabolizing Enzyme and Transporter Genes: Comprehensive Assessment in 3 Major East Asian Subpopulations With Comparison to Caucasians and Africans

(2010) Michael Man et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effects of the Serotonin 1A, 2A, 2C, 3A, and 3B and Serotonin Transporter Gene Polymorphisms on the Occurrence of Paroxetine Discontinuation Syndrome

(2010) Yusuke Murata et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response

(2010) Ming-Hsien Tsai et al.   PHARMACOGENOMICS

Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults

(2010) Robert Howland   Neuropsychiatric Disease and Treatment

Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17

(2009) Alain Li-Wan-Po et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

In Vitro and In Vivo Evaluations of Cytochrome P450 1A2 Interactions with Duloxetine

(2009) Evelyn D Lobo et al.   CLINICAL PHARMACOKINETICS

Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy

(2009) F.F. Tessa Ververs et al.   CLINICAL PHARMACOKINETICS

High Frequency of Occurrence of CYP2D6 Gene Duplication/Multiduplication Indicating Ultrarapid Metabolism Among Suicide Cases

(2009) A L Zackrisson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Cytochrome P450 2D6 Genotyping

(2009) Julia Kirchheiner et al.   CNS DRUGS

Clinical utility of desvenlafaxine 50 mg/d for treating MDD: a review of two randomized placebo-controlled trials for the practicing physician

(2009) Sujana Reddy et al.   CURRENT MEDICAL RESEARCH AND OPINION

Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine–alprazolam interaction in patients with psychosomatic disease

(2009) Hideyo Sugahara et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker

(2009) L. Noehr-Jensen et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Evaluation of the influence of sex and CYP2C19 and CYP2D6 polymorphisms in the disposition of citalopram

(2009) Salvador Fudio et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes are not associated with response and remission in a sample of depressive patients

(2009) Alessandro Serretti et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Effect of Age, Weight, and CYP2C19 Genotype on Escitalopram Exposure

(2009) Yuyan Jin et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Assessment of CYP2C19 genetic polymorphisms in a korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles

(2009) K.-A. Kim et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Venlafaxine Metabolism as a Marker of Cytochrome P450 Enzyme 2D6 Metabolizer Status

(2009) Alice I. Nichols et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity

(2009) P A H M Wijnen et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Agomelatine Treatment of Major Depressive Disorder

(2008) Christian R Dolder et al.   ANNALS OF PHARMACOTHERAPY

Steady-State Concentrations of Mirtazapine, N-Desmethylmirtazapine, 8-Hydroxymirtazapine and their Enantiomers in Relation to Cytochrome P450 2D6 Genotype, Age and Smoking Behaviour

(2008) Anna-Britta Lind et al.   CLINICAL PHARMACOKINETICS

Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: An update

(2008) Edoardo Spina et al.   CLINICAL THERAPEUTICS

Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects

(2008) Staffan Ohlsson Rosenborg et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacokinetic Genes Do Not Influence Response or Tolerance to Citalopram in the STAR*D Sample

(2008) Eric J. Peters et al.   PLoS One

Dose-Dependent Effect of the CYP2D6 Genotype on the Steady-state Fluvoxamine Concentration

(2008) Junzo Watanabe et al.   THERAPEUTIC DRUG MONITORING

The CYP2D6 polymorphism in relation to the metabolism of amitriptyline and nortriptyline in the Faroese population

(2007) Jónrit Halling et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY