Activated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2

SLC44A2 deficient mice have a reduced response in stenosis but not in hypercoagulability driven venous thrombosis

(2020) Julia Tilburg et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil Extracellular Traps in Arterial and Venous Thrombosis

(2019) Elodie Laridan et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Association between SLC44A2 rs2288904 polymorphism and risk of recurrent venous thromboembolism among Thai patients

(2019) Dollapak Apipongrat et al.   THROMBOSIS RESEARCH

Endothelial Cell–Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E–Deficient MiceHighlights

(2018) Prakash Doddapattar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hemodynamic force triggers rapid NETosis within sterile thrombotic occlusions

(2018) X. Yu et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Characterization of hemostasis in mice lacking the novel thrombosis susceptibility gene Slc44a2

(2018) Julia Tilburg et al.   THROMBOSIS RESEARCH

Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling

(2017) Maria E. Lopes Pires et al.   PLoS One

Pondering neutrophil extracellular traps with healthy skepticism

(2016) William M. Nauseef et al.   CELLULAR MICROBIOLOGY

Cobalt(III)-Mediated Permanent and Stable Immobilization of Histidine-Tagged Proteins on NTA-Functionalized Surfaces

(2016) Seraphine V. Wegner et al.   CHEMISTRY-A EUROPEAN JOURNAL

Evolving Treatments for Arterial and Venous Thrombosis

(2016) Noel C. Chan et al.   CIRCULATION RESEARCH

SLC44A2 single nucleotide polymorphisms, isoforms, and expression: Association with severity of Meniere's disease?

(2016) Thankam S. Nair et al.   GENOMICS

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

(2016) David A. Hinds et al.   HUMAN MOLECULAR GENETICS

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor

(2016) Wei Deng et al.   Nature Communications

Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals

(2016) Lining Ju et al.   eLife

Platelets: New Bricks in the Building of Neutrophil Extracellular Traps

(2016) Agostina Carestia et al.   Frontiers in Immunology

Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism

(2015) Marine Germain et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Choline Transporter-Like Protein-2Significance

(2015) Behnaz Bayat et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice

(2015) S. Verhenne et al.   BLOOD

Immunosurveillance of the Liver by Intravascular Effector CD8 + T Cells

(2015) Luca G. Guidotti et al.   CELL

Flow-driven assembly of VWF fibres and webs in in vitro microvessels

(2015) Ying Zheng et al.   Nature Communications

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

Venous thrombosis

(2015) Alisa S. Wolberg et al.   Nature Reviews Disease Primers

Misfolding of vWF to Pathologically Disordered Conformations Impacts the Severity of von Willebrand Disease

(2014) Alexander Tischer et al.   BIOPHYSICAL JOURNAL

A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets

(2014) J. D. Welsh et al.   BLOOD

Identification of a juxtamembrane mechanosensitive domain in the platelet mechanosensor glycoprotein Ib-IX complex

(2014) W. Zhang et al.   BLOOD

Src family kinases: at the forefront of platelet activation

(2014) Y. A. Senis et al.   BLOOD

Of von Willebrand factor and platelets

(2014) Marijke Bryckaert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structural Basis of Regulation of von Willebrand Factor Binding to Glycoprotein Ib

(2014) Mark A. Blenner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelets: at the nexus of antimicrobial defence

(2014) Michael R. Yeaman   NATURE REVIEWS MICROBIOLOGY

Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A

(2014) Anurag Kumar Gupta et al.   PLoS One

Neutrophils scan for activated platelets to initiate inflammation

(2014) Vinatha Sreeramkumar et al.   SCIENCE

Identification of platelet function defects by multi-parameter assessment of thrombus formation

(2014) Susanne M. de Witt et al.   Nature Communications

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

(2013) T. J. Stalker et al.   BLOOD

Treatment of Acute Venous Thromboembolism With Dabigatran or Warfarin and Pooled Analysis

(2013) Sam Schulman et al.   CIRCULATION

Crossroads of coagulation and innate immunity: the case of deep vein thrombosis

(2013) C. Schulz et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

(2013) Connie H Y Wong et al.   NATURE IMMUNOLOGY

Extended Anticoagulation in Venous Thromboembolism

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

(2013) K. Martinod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis

(2013) Yan Hou et al.   THROMBOSIS AND HAEMOSTASIS

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ADAMTS13 deficiency exacerbates VWF-dependent acute myocardial ischemia/reperfusion injury in mice

(2012) C. Gandhi et al.   BLOOD

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

(2012) T. A. Fuchs et al.   BLOOD

Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis

(2012) Braedon McDonald et al.   Cell Host & Microbe

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice

(2012) M. M. KHAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

BLUEPRINT to decode the epigenetic signature written in blood

(2012) David Adams et al.   NATURE BIOTECHNOLOGY

Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl3-induced occlusive thrombus formation in the inferior vena cava of mice

(2012) M.V. Joglekar et al.   PLATELETS

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetics of Venous Thrombosis: Insights from a New Genome Wide Association Study

(2011) Marine Germain et al.   PLoS One

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

(2010) A. Brill et al.   BLOOD

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

(2010) D. Lievens et al.   BLOOD

von Willebrand factor promotes leukocyte extravasation

(2010) B. Petri et al.   BLOOD

GPIbα-selective activation of platelets induces platelet signaling events comparable to GPVI activation events

(2010) Elizabeth E. Gardiner et al.   PLATELETS

Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury

(2009) Mark R. Looney et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetics of venous thrombosis

(2009) F. R. ROSENDAAL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibα, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex

(2009) F.-T. MU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism

(2009) Sam Schulman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF

(2008) Tadayuki Yago et al.   JOURNAL OF CLINICAL INVESTIGATION

Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice

(2008) Wolfgang Bergmeier et al.   THROMBOSIS AND HAEMOSTASIS