[3+2] Cycloaddition of Trifluoromethylated N ‐Acylhydrazones with Azomethine Ylides: Synthesis of Trifluoromethylated Imidazolidines

Tin-Mediated One-pot Preparation of β-Trifluoromethyl-β- acylhydrazonyl Carbonyl Compounds

(2019) Ke-Hu Wang et al.   Asian Journal of Organic Chemistry

Construction of Chiral β-Trifluoromethyl Alcohols Enabled by Catalytic Enantioselective Aldol-Type Reaction of CF3CHN2

(2019) Meng-Yu Rong et al.   ORGANIC LETTERS

Asymmetric Michael Reaction of α-CF3 Thioester and α,β-Unsaturated Aldehyde Catalyzed by Diphenylprolinol Silyl Ether

(2019) Yujiro Hayashi et al.   ORGANIC LETTERS

Metal-Free Construction of the C(sp3)–CF3 Bond: Trifluoromethylation of Hydrazones with Togni’s Reagent under Mild Conditions

(2019) Huiying Zeng et al.   ORGANIC LETTERS

A Facile Synthesis of CF3-Substituted Pyrazolidines and Pyrazolines

(2018) Lili Liu et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Trifluoroethyl Pyrazolines via Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of β,γ-Unsaturated Hydrazones

(2018) Bingbing Chang et al.   JOURNAL OF ORGANIC CHEMISTRY

Cascade Oxidation/Halogenoaminocyclization Reaction of Trifluoromethylated Homoallylic N-Acylhydrazines: Metal-free Synthesis of CF3-Substituted Pyrazolines

(2018) Yuxiang Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Tin-Powder-Promoted One-Pot Synthesis of 5-Trifluoromethyl-5-aryl-3-methylidenepyrrolidin-2-ones

(2018) Ke-Hu Wang et al.   SYNTHESIS-STUTTGART

[3+2] Cycloaddition of Trifluoromethylated N-Acylhydrazones with Maleates: Synthesis of Trifluoromethylated Pyrazolidines

(2018) Danfeng Huang et al.   SYNTHESIS-STUTTGART

Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imines: The Expanded Scope and Mechanism Insights

(2018) Liang Wei et al.   JOURNAL OF ORGANIC CHEMISTRY

Zinc-Mediated Mannich-Type Reaction of 2,2,2-Trifluorodiazoethane with Imines: Access to β-CF3-Amines

(2018) Ran Guo et al.   ORGANIC LETTERS

Asymmetric Synthesis of α-Trifluoromethyl Pyrrolidines through Organocatalyzed 1,3-Dipolar Cycloaddition Reaction

(2017) Zhenghao Dong et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of trifluoromethylated pyrazolidines by [3 + 2] cycloaddition

(2017) Xiansha Peng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of Allylic Oximes: Synthesis of Trifluoromethylated Isoxazolines

(2017) Weigang Zhang et al.   ORGANIC LETTERS

Trifluoromethylation of Secondary Nitroalkanes

(2017) Amber A. S. Gietter-Burch et al.   ORGANIC LETTERS

Trifluoromethyl nitrogen heterocycles: synthetic aspects and potential biological targets

(2016) F. Meyer   CHEMICAL COMMUNICATIONS

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

(2016) Yu Zhou et al.   CHEMICAL REVIEWS

Phenyliodonium diacetate mediated carbotrifluoromethylation of N-acylhydrazones

(2016) Weigang Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-pot preparation of trifluoromethylated homoallylic N-acylhydrazines or α-methylene-γ-lactams from acylhydrazines, trifluoroacetaldehyde methyl hemiacetal, allyl bromide and tin

(2016) Ganggang Du et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Progress of modern agricultural chemistry and future prospects

(2015) Peter Jeschke   PEST MANAGEMENT SCIENCE

Copper(II)-Catalyzed Oxidative Esterification of Substituted p-Cresols under Ligand- and Additive-Free Conditions

(2015) Ya-Fei Ji et al.   SYNLETT

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

(2014) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Addition of CF3 across unsaturated moieties: a powerful functionalization tool

(2014) Estíbaliz Merino et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric construction of fluorinated imidazolidines via Cu(i)-catalyzed exo′-selective 1,3-dipolar cycloaddition of azomethine ylides with fluorinated imines

(2013) Qing-Hua Li et al.   CHEMICAL COMMUNICATIONS

4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions

(2013) Yingle Liu et al.   TETRAHEDRON LETTERS

Thiourea-Catalyzed Enantioselective Fluorination of β-Keto Esters

(2012) Junxing Xu et al.   ADVANCED SYNTHESIS & CATALYSIS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Diastereoselective Silver-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imine

(2010) Haibo Xie et al.   JOURNAL OF ORGANIC CHEMISTRY

α-Trifluoromethylated Carbanion Synthons

(2008) Kenji Uneyama et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS