Propagation of human prostate tissue from induced pluripotent stem cells

Generation of human iPSCs from fetal prostate fibroblasts HPrF

(2019) Zuzana Kahounová et al.   Stem Cell Research

N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer

(2019) Adeline Berger et al.   JOURNAL OF CLINICAL INVESTIGATION

The long tail of oncogenic drivers in prostate cancer

(2018) Joshua Armenia et al.   NATURE GENETICS

A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

(2018) Lay Teng Ang et al.   Cell Reports

Preclinical Models of Prostate Cancer: Patient-Derived Xenografts, Organoids, and Other Explant Models

(2018) Gail P. Risbridger et al.   Cold Spring Harbor Perspectives in Medicine

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Intra-tumour diversification in colorectal cancer at the single-cell level

(2018) Sophie F. Roerink et al.   NATURE

Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses

(2018) Qiuhui Li et al.   Nature Communications

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

(2018) Zuzana Kahounová et al.   Stem Cell Research

ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells

(2017) E M Langer et al.   ONCOGENE

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer

(2017) Ping Mu et al.   SCIENCE

A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue

(2017) Flaminia Talos et al.   Nature Communications

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

(2017) Jonghyeob Lee et al.   Nature Communications

Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids

(2017) Kenji Unno et al.   Oncotarget

Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates

(2017) Mohammad Moad et al.   Cell Reports

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

(2017) Gun-Sik Cho et al.   Cell Reports

Prognostic and predictive biomarkers in prostate cancer: latest evidence and clinical implications

(2017) Naoki Terada et al.   Therapeutic Advances in Medical Oncology

N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells

(2016) John K. Lee et al.   CANCER CELL

Modeling Development and Disease with Organoids

(2016) Hans Clevers   CELL

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay

(2016) Jung Wook Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer

(2016) Jennifer L. Bishop et al.   Cancer Discovery

Integrative Clinical Genomics of Advanced Prostate Cancer

(2015) Dan Robinson et al.   CELL

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Spatial genomic heterogeneity within localized, multifocal prostate cancer

(2015) Paul C Boutros et al.   NATURE GENETICS

Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure

(2015) Esther L. Calderon-Gierszal et al.   PLoS One

Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis

(2014) P. L. Berger et al.   CANCER RESEARCH

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

(2014) Dong Gao et al.   CELL

Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

(2014) Wouter R. Karthaus et al.   CELL

Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

(2014) Kyle M. Loh et al.   Cell Stem Cell

Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development

(2014) Sarah L. Bryant et al.   DEVELOPMENTAL BIOLOGY

A Novel Model of Urinary Tract Differentiation, Tissue Regeneration, and Disease: Reprogramming Human Prostate and Bladder Cells into Induced Pluripotent Stem Cells

(2013) Mohammad Moad et al.   EUROPEAN UROLOGY

Induced Pluripotency of Human Prostatic Epithelial Cells

(2013) Hongjuan Zhao et al.   PLoS One

Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin

(2013) Oh-Joon Kwon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells

(2013) T. Stoyanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Reprogramming of prostate cancer-associated stromal cells to embryonic stem-like

(2012) Eneida F. Vêncio et al.   PROSTATE

Altered TGF-β Signaling in a Subpopulation of Human Stromal Cells Promotes Prostatic Carcinogenesis

(2011) Omar E. Franco et al.   CANCER RESEARCH

In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells

(2011) John K Blackwood et al.   JOURNAL OF PATHOLOGY

Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

(2011) Kitai Kim et al.   NATURE BIOTECHNOLOGY

Identification of a Cell of Origin for Human Prostate Cancer

(2010) A. S. Goldstein et al.   SCIENCE

A luminal epithelial stem cell that is a cell of origin for prostate cancer

(2009) Xi Wang et al.   NATURE