Osteocalcin promotes bone mineralization but is not a hormone

An osteocalcin-deficient mouse strain without endocrine abnormalities

(2020) Cassandra R. Diegel et al.   PLoS Genetics

Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass

(2020) Takeshi Moriishi et al.   PLoS Genetics

Metabolic and skeletal homeostasis are maintained in full locus GPRC6A knockout mice

(2019) Christinna V. Jørgensen et al.   Scientific Reports

Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology

(2016) Laura J. Lambert et al.   Disease Models & Mechanisms

Osteocalcin is necessary and sufficient to maintain muscle mass in older mice

(2016) Paula Mera et al.   Molecular Metabolism

Reproducibility of Results in Preclinical Studies: A Perspective From the Bone Field

(2014) Stavros C Manolagas et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions

(2013) Franck Oury et al.   CELL

The l-α-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in l-arginine-induced insulin release

(2012) Sanela Smajilovic et al.   AMINO ACIDS

Endocrine Regulation of Male Fertility by the Skeleton

(2011) Franck Oury et al.   CELL

No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions

(2008) Petrine Wellendorph et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY