Potential of the natural products against leishmaniasis in Old World - a review of in-vitro studies

Visceral Leishmaniasis

(2019) Johan van Griensven et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Need for sustainable approaches in antileishmanial drug discovery

(2019) Sarah Hendrickx et al.   PARASITOLOGY RESEARCH

Anti-infective activities of 11 plants species used in traditional medicine in Malaysia

(2018) Nadiah Syafiqah Nor Azman et al.   EXPERIMENTAL PARASITOLOGY

Phytochemical study of Piliostigma thonningii, a medicinal plant grown in Nigeria

(2018) Michael Afolayan et al.   MEDICINAL CHEMISTRY RESEARCH

Conventional Versus Natural Alternative Treatments for Leishmaniasis: A Review

(2018) Luiz Felipe Domingues Passero et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Recent advances in Leishmania reverse genetics: Manipulating a manipulative parasite

(2017) Samuel M. Duncan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The sesquiterpene (−)-α-bisabolol is active against the causative agents of Old World cutaneous leishmaniasis through the induction of mitochondrial-dependent apoptosis

(2016) V. Corpas-López et al.   APOPTOSIS

Induction of apoptosis by zerumbone isolated from Zingiber zerumbet (L.) Smith in protozoan parasite Leishmania donovani due to oxidative stress

(2016) Debarati Mukherjee et al.   Brazilian Journal of Infectious Diseases

Plants as Antileishmanial Agents: Current Scenario

(2016) Nazif Ullah et al.   PHYTOTHERAPY RESEARCH

Ethnomedicines and anti-parasitic activities of Pakistani medicinal plants against Plasmodia and Leishmania parasites

(2016) Akash Tariq et al.   Annals of Clinical Microbiology and Antimicrobials

Exploitation of Cytotoxicity of Some Essential Oils for Translation in Cancer Therapy

(2015) Rossella Russo et al.   Evidence-based Complementary and Alternative Medicine

(−)-α-Bisabolol, a Promising Oral Compound for the Treatment of Visceral Leishmaniasis

(2015) Victoriano Corpas-López et al.   JOURNAL OF NATURAL PRODUCTS

In Vitro Infectivity Assessment by Drug Susceptibility Comparison of Recombinant <i>Leishmania major</i> Expressing Enhanced Green Fluorescent Protein or EGFP-Luciferase Fused Genes with Wild-Type Parasite

(2015) Somayeh Sadeghi et al.   KOREAN JOURNAL OF PARASITOLOGY

Antileishmanial and Cytotoxic Compounds from Valeriana wallichii and Identification of a Novel Nepetolactone Derivative

(2015) Jan Glaser et al.   MOLECULES

Hit and lead criteria in drug discovery for infectious diseases of the developing world

(2015) Kei Katsuno et al.   NATURE REVIEWS DRUG DISCOVERY

Leishmanicidal Active Withanolides from a Pakistani Medicinal Plant, Withania coagulans

(2015) Masanori Kuroyanagi et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis

(2015) Eduardo S. Yamamoto et al.   PLoS One

Evaluation of theIn VitroAntiplasmodial, Antileishmanial, and Antitrypanosomal Activity of Medicinal Plants Used in Saudi and Yemeni Traditional Medicine

(2014) Ramzi A. Mothana et al.   Evidence-based Complementary and Alternative Medicine

In Vitro Antiprotozoal and Cytotoxic Activity of Ethnopharmacologically Selected Guinean Plants

(2014) Mohammed Traore et al.   PLANTA MEDICA

Antileishmanial, Toxicity, and Phytochemical Evaluation of Medicinal Plants Collected from Pakistan

(2014) Naseer Ali Shah et al.   Biomed Research International

Evaluation of antileishmanial activities of triglycerides isolated from roots of Moringa stenopetala

(2013) Banchiwossen Bekele et al.   MEDICINAL CHEMISTRY RESEARCH

In Vitro Antiprotozoal Activity of Triterpenoid Constituents of Kleinia odora Growing in Saudi Arabia

(2013) Nawal Al Musayeib et al.   MOLECULES

Antiprotozoal Isoflavan Quinones from Abrus precatorius ssp. africanus

(2013) Yoshie Hata et al.   PLANTA MEDICA

Antiprotozoal Screening of 60 South African Plants, and the Identification of the Antitrypanosomal Germacranolides Schkuhrin I and II

(2013) Tsholofelo Mokoka et al.   PLANTA MEDICA

Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)

(2013) Tsholofelo A. Mokoka et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Activity of Thymus capitellatus volatile extract, 1,8-cineole and borneol against Leishmania species

(2013) M. Machado et al.   VETERINARY PARASITOLOGY

2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani

(2012) Néstor M. Carballeira et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Efficacy of Miltefosine in the Treatment of Visceral Leishmaniasis in India After a Decade of Use

(2012) S. Sundar et al.   CLINICAL INFECTIOUS DISEASES

The Potential of Secondary Metabolites from Plants as Drugs or Leads Against Protozoan Neglected Diseases - Part I

(2012) T.J. Schmidt et al.   CURRENT MEDICINAL CHEMISTRY

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

An antileishmanial prenyloxy-naphthoquinone from roots ofPlumbago zeylanica

(2012) Bhuwan B. Mishra et al.   NATURAL PRODUCT RESEARCH

In vitroantileishmanial, antiplasmodial and cytotoxic activities of a new ventiloquinone and five known triterpenes fromParinari excelsa

(2012) Barthélemy Attioua et al.   PHARMACEUTICAL BIOLOGY

Leishmanicidal activity assessment of olive tree extracts

(2012) Joannis D. Kyriazis et al.   PHYTOMEDICINE

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Chemical Studies on an Endemic Philippine Plant: Sulfated Glucoside and seco-A-Ring Triterpenoids from Dillenia philippinensis

(2011) Rene Angelo Sarmiento Macahig et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

In vitro antitrypanosomal and antileishmanial activity of plants used in Benin in traditional medicine and bio-guided fractionation of the most active extract

(2011) Joanne Bero et al.   JOURNAL OF ETHNOPHARMACOLOGY

Evaluation of antileishmanial, cytotoxic and antioxidant activities of essential oils extracted from plants issued from the leishmaniasis-endemic region of Sned (Tunisia)

(2011) S. Ben Hadj Ahmed et al.   NATURAL PRODUCT RESEARCH

In vitro antileishmanial and antitrypanosomal activities of five medicinal plants from Burkina Faso

(2011) W. R. Sawadogo et al.   PARASITOLOGY RESEARCH

Current Approaches to Discover Marine Antileishmanial Natural Products

(2011) André Tempone et al.   PLANTA MEDICA

Anti-leishmanial and Anti-cancer Activities of a Pentacyclic Triterpenoid Isolated from the Leaves of Terminalia arjuna Combretaceae

(2011) B Moulisha et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

How Many Species Are There on Earth and in the Ocean?

(2011) Camilo Mora et al.   PLOS BIOLOGY

Essential-Oil Composition, Antileishmanial, and Toxicity Study ofArtemisia abyssinicaandSatureja punctatassp.punctatafrom Ethiopia

(2010) Yinebeb Tariku et al.   CHEMISTRY & BIODIVERSITY

Leishmania donovani: Assessment of leishmanicidal effects of herbal extracts obtained from plants in the visceral leishmaniasis endemic area of Bihar, India

(2010) Shubhankar K. Singh et al.   EXPERIMENTAL PARASITOLOGY

Fluorescent Leishmania species: Development of stable GFP expression and its application for in vitro and in vivo studies

(2010) Azam Bolhassani et al.   EXPERIMENTAL PARASITOLOGY

In vitro antiprotozoal, antimicrobial and antitumor activity of Pavetta crassipes K. Schum leaf extracts

(2010) Elhadj S. Baldé et al.   JOURNAL OF ETHNOPHARMACOLOGY

Valeriana wallichii root extracts and fractions with activity against Leishmania spp

(2010) Subhalakshmi Ghosh et al.   PARASITOLOGY RESEARCH

In Vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease

(2010) Essam Abdel-Sattar et al.   PHYTOTHERAPY RESEARCH

Peganine hydrochloride dihydrate an orally active antileishmanial agent

(2009) Tanvir Khaliq et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Leishmanicidal Active Constituents from Nepalese Medicinal Plant Tulsi (Ocimum sanctum L.)

(2009) Akiko Suzuki et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Evaluation of anti-leishmanial activity of selected Indian plants known to have antimicrobial properties

(2009) Umakant Sharma et al.   PARASITOLOGY RESEARCH

Nuphar lutea: In vitro anti-leishmanial activity against Leishmania major promastigotes and amastigotes

(2009) J. El-On et al.   PHYTOMEDICINE

WR279,396, a Third Generation Aminoglycoside Ointment for the Treatment of Leishmania major Cutaneous Leishmaniasis: A Phase 2, Randomized, Double Blind, Placebo Controlled Study

(2009) Afif Ben Salah et al.   PLoS Neglected Tropical Diseases

Advancing Drug Innovation for Neglected Diseases—Criteria for Lead Progression

(2009) Solomon Nwaka et al.   PLoS Neglected Tropical Diseases

Castalagin from Anogeissus leiocarpus mediates the killing of Leishmania in vitro

(2008) M. N. Shuaibu et al.   PARASITOLOGY RESEARCH

Antileishmanial Compounds fromCordia fragrantissima Collected in Burma (Myanmar)

(2007) Kanami Mori et al.   JOURNAL OF NATURAL PRODUCTS