Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats

Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke

(2018) Chen Chen et al.   Journal of Neuroinflammation

Hypoxia Inducible Factor 1α Plays a Key Role in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Rats

(2018) Jian Yang et al.   Journal of the American Heart Association

Salidroside Inhibits Inflammation Through PI3K/Akt/HIF Signaling After Focal Cerebral Ischemia in Rats

(2017) Yicong Wei et al.   INFLAMMATION

Gut dysbiosis is associated with metabolism and systemic inflammation in patients with ischemic stroke

(2017) Kazuo Yamashiro et al.   PLoS One

The Interventional Effect of Remote Ischemic Preconditioning on Cerebral Small Vessel Disease: A Pilot Randomized Clinical Trial

(2016) Taomian Mi et al.   EUROPEAN NEUROLOGY

Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue

(2016) Thuy-Vi V. Nguyen et al.   Acta Neuropathologica Communications

Limb remote ischemic postconditioning protects cerebral ischemia from injury associated with expression of HIF-1α in rats

(2015) Yonghua Zong et al.   BMC NEUROSCIENCE

Electroacupuncture Pretreatment Attenuates Cerebral Ischemic Injury via Notch Pathway-Mediated Up-Regulation of Hypoxia Inducible Factor-1α in Rats

(2015) Yu Zhao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Remote Ischemic Preconditioning-Mediated Neuroprotection against Stroke is Associated with Significant Alterations in Peripheral Immune Responses

(2015) Zong-Jian Liu et al.   CNS Neuroscience & Therapeutics

White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke

(2015) Jun Suenaga et al.   EXPERIMENTAL NEUROLOGY

A critical review of mechanisms regulating remote preconditioning-induced brain protection

(2015) Robert Meller et al.   JOURNAL OF APPLIED PHYSIOLOGY

Akt protects the heart against ischaemia-reperfusion injury by modulating mitochondrial morphology

(2015) Sang-Bing Ong et al.   THROMBOSIS AND HAEMOSTASIS

Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC

(2015) Silvia Martin-Puig et al.   Frontiers in Physiology

Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury

(2014) Pinelopi P. Kapitsinou et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential effects of aging and sex on stroke induced inflammation across the lifespan

(2013) Bharti Manwani et al.   EXPERIMENTAL NEUROLOGY

Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice

(2013) Marie Orre et al.   NEUROBIOLOGY OF AGING

Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart

(2013) Z. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Rita V Krishnamurthi et al.   Lancet Global Health

The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis

(2012) Thorsten R. Doeppner et al.   BRAIN

Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats

(2012) Sheng Hu et al.   BRAIN RESEARCH

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Protection by silibinin against experimental ischemic stroke: Up-regulated pAkt, pmTOR, HIF-1α and Bcl-2, down-regulated Bax, NF-κB expression

(2012) Chaohui Wang et al.   NEUROSCIENCE LETTERS

The Chronic Protective Effects of Limb Remote Preconditioning and the Underlying Mechanisms Involved in Inflammatory Factors in Rat Stroke

(2012) Dingtai Wei et al.   PLoS One

Hypoxia-Inducible Factor 1-α-AA-Modified Bone Marrow Stem Cells Protect PC12 Cells from Hypoxia-Induced Apoptosis, Partially Through VEGF/PI3K/Akt/FoxO1 Pathway

(2012) Qian Zhong et al.   STEM CELLS AND DEVELOPMENT

Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α

(2011) Molly E. Ogle et al.   NEUROBIOLOGY OF DISEASE

Remote ischemic post-conditioning reduced brain damage in experimental ischemia/reperfusion injury

(2011) Changhong Ren et al.   NEUROLOGICAL RESEARCH

Enhanced IL-1β Production in response to the activation of hippocampal glial cells impairs neurogenesis in aged mice

(2010) Naoko Kuzumaki et al.   SYNAPSE

Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging

(2009) Mary L. Modrick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Limb remote ischemic postconditioning protects against focal ischemia in rats

(2009) Chuancheng Ren et al.   BRAIN RESEARCH

Prolyl Hydroxylase Inhibitors Depend on Extracellular Glucose and Hypoxia-Inducible Factor (HIF)-2  to Inhibit Cell Death Caused by Nerve Growth Factor (NGF) Deprivation: Evidence that HIF-2  Has a Role in NGF-Promoted Survival of Sympathetic Neurons

(2009) D. J. Lomb et al.   MOLECULAR PHARMACOLOGY

Age-Related Alterations in Reactivity of Cerebral Arterioles: Role of Oxidative Stress

(2008) William G. Mayhan et al.   MICROCIRCULATION