Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC

TRPV1 and TRPV4 channels: Potential therapeutic targets for ischemic conditioning-induced cardioprotection

(2015) Puneet Kaur Randhawa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Akt protects the heart against ischaemia-reperfusion injury by modulating mitochondrial morphology

(2015) Sang-Bing Ong et al.   THROMBOSIS AND HAEMOSTASIS

HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore

(2014) Sang-Ging Ong et al.   CARDIOVASCULAR RESEARCH

High-dose erythropoietin for tissue protection

(2014) Anton Lund et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Intracoronary injection of adenosine before reperfusion in patients with ST-segment elevation myocardial infarction: A randomized controlled clinical trial

(2014) David Garcia-Dorado et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury

(2014) Pinelopi P. Kapitsinou et al.   JOURNAL OF CLINICAL INVESTIGATION

Remote ischaemic preconditioning involves signalling through the SDF-1α/CXCR4 signalling axis

(2013) Sean M. Davidson et al.   BASIC RESEARCH IN CARDIOLOGY

Crosstalk between oxygen- and nitric oxide-dependent signaling pathways in angiogenesis

(2013) Peter Fraisl   EXPERIMENTAL CELL RESEARCH

Erythropoietin in cardiac disease

(2013) Vittoria Mastromarino et al.   Journal of Cardiovascular Medicine

Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning

(2013) Hussein Kalakech et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection

(2013) Risto Kerkelä et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart

(2013) Z. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remote ischemic preconditioning regulates HIF-1α levels, apoptosis and inflammation in heart tissue of cardiosurgical patients: a pilot experimental study

(2012) Martin Albrecht et al.   BASIC RESEARCH IN CARDIOLOGY

The Bispecific SDF1-GPVI Fusion Protein Preserves Myocardial Function After Transient Ischemia in Mice

(2012) Melanie Ziegler et al.   CIRCULATION

Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB

(2012) Suresh Kumar Verma et al.   CIRCULATION

Interleukin-10 activates Toll-like receptor 4 and requires MyD88 for cardiomyocyte survival

(2012) Ashim K. Bagchi et al.   CYTOKINE

Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

(2011) Daniel Tello et al.   Cell Metabolism

Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 Knock Out Protects from Acute Myocardial Ischemic Injury

(2011) Marion Hölscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Akt Regulates IL-10 Mediated Suppression of TNFα-Induced Cardiomyocyte Apoptosis by Upregulating Stat3 Phosphorylation

(2011) Sanjiv Dhingra et al.   PLoS One

Acute Vhl Gene Inactivation Induces Cardiac HIF-Dependent Erythropoietin Gene Expression

(2011) Marta Miró-Murillo et al.   PLoS One

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury

(2010) Jaana Hyvärinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice

(2010) Kazutaka Ueda et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression

(2010) Z Chen et al.   ONCOGENE

Molecular Basis of Cardioprotection by Erythropoietin

(2010) D. Burger et al.   Current Molecular Pharmacology

IL-10 attenuates TNF- -induced NF B pathway activation and cardiomyocyte apoptosis

(2009) S. Dhingra et al.   CARDIOVASCULAR RESEARCH

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

(2009) Stephen Y. Chan et al.   Cell Metabolism

Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy

(2009) Jaya Krishnan et al.   Cell Metabolism

In vivoRemote Delivery of DNA Encoding for Hypoxia-inducible Factor 1 Alpha Reduces Myocardial Infarct Size

(2009) Gabor Czibik et al.   CTS-Clinical and Translational Science

Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury

(2009) Martin Schneider et al.   GASTROENTEROLOGY

A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo

(2009) Y. A. Minamishima et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

Lives of a Heart Cell: Tracing the Origins of Cardiac Progenitors

(2008) Silvia Martin-Puig et al.   Cell Stem Cell

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION

Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms

(2008) Mohd Shahid et al.   EXPERIMENTAL PHYSIOLOGY

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

(2008) Chun-Wun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Erythropoietin in heart and vessels: focus on transcription and signalling pathways

(2008) Francesca Marzo et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases

(2008) Ravi Kant et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Signal mechanism activated by erythropoietin preconditioning and remote renal preconditioning-induced cardioprotection

(2008) Vishal Diwan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hypoxia-Inducible Factor-Dependent Degeneration, Failure, and Malignant Transformation of the Heart in the Absence of the von Hippel-Lindau Protein

(2008) L. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

(2008) Julián Aragonés et al.   NATURE GENETICS

Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

(2008) Elizabeth Murphy et al.   PHYSIOLOGICAL REVIEWS

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

(2007) Y. A. Minamishima et al.   BLOOD