RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

A systematic review of biomarkers to detect active tuberculosis

(2019) Emily MacLean et al.   Nature Microbiology

Host-response-based gene signatures for tuberculosis diagnosis: A systematic comparison of 16 signatures

(2019) Hayley Warsinske et al.   PLOS MEDICINE

Prospective evaluation of host biomarkers other than interferon gamma in QuantiFERON Plus supernatants as candidates for the diagnosis of tuberculosis in symptomatic individuals

(2019) Portia M. Manngo et al.   JOURNAL OF INFECTION

Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis

(2018) Sara Suliman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis

(2018) Hanif Esmail et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnostic performance of an optimized transcriptomic signature of risk of tuberculosis in cryopreserved peripheral blood mononuclear cells

(2018) Fatoumatta Darboe et al.   TUBERCULOSIS

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

(2018) Akul Singhania et al.   Nature Communications

Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis

(2018) Novel N. Chegou et al.   Scientific Reports

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images

(2018) Stephanus T. Malherbe et al.   EJNMMI Research

A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts

(2018) Fergal J. Duffy et al.   Frontiers in Immunology

A stratified approach to tuberculosis treatment

(2018) Gavin J. Churchyard   NATURE MEDICINE

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

(2018) Marjorie Z. Imperial et al.   NATURE MEDICINE

Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting

(2018) Yuri F. van der Heijden et al.   TUBERCULOSIS

Effect of rifampicin and efavirenz on moxifloxacin concentrations when co-administered in patients with drug-susceptible TB

(2017) Anushka Naidoo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis

(2017) David W Dowdy et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial

(2017) Gregory L Calligaro et al.   LANCET INFECTIOUS DISEASES

Host blood RNA signatures predict the outcome of tuberculosis treatment

(2017) Ethan G. Thompson et al.   TUBERCULOSIS

Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

(2017) Thomas J. Scriba et al.   PLoS Pathogens

HIV-1 Env Glycoprotein Phenotype along with Immune Activation Determines CD4 T Cell Loss in HIV Patients

(2016) Anjali Joshi et al.   JOURNAL OF IMMUNOLOGY

A blood RNA signature for tuberculosis disease risk: a prospective cohort study

(2016) Daniel E Zak et al.   LANCET

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

(2016) Stephanus T Malherbe et al.   NATURE MEDICINE

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB

(2016) Novel N Chegou et al.   THORAX

Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis

(2016) Timothy E Sweeney et al.   Lancet Respiratory Medicine

The Dynamics of QuantiFERON-TB Gold In-Tube Conversion and Reversion in a Cohort of South African Adolescents

(2015) Jason R. Andrews et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

RePORT International: Advancing Tuberculosis Biomarker Research Through Global Collaboration

(2015) Carol D. Hamilton et al.   CLINICAL INFECTIOUS DISEASES

Concise gene signature for point-of-care classification of tuberculosis

(2015) J. Maertzdorf et al.   EMBO Molecular Medicine

National tuberculosis prevalence surveys in Asia, 1990-2012: an overview of results and lessons learned

(2015) Ikushi Onozaki et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

(2014)   NATURE BIOTECHNOLOGY

Virulence and Pathogenesis of HIV-1 Infection: An Evolutionary Perspective

(2014) C. Fraser et al.   SCIENCE

Systemic Effects of Inflammation on Health during Chronic HIV Infection

(2013) Steven G. Deeks et al.   IMMUNITY

Immune activation and HIV persistence: implications for curative approaches to HIV infection

(2013) Nichole R. Klatt et al.   IMMUNOLOGICAL REVIEWS

Distinct Phases of Blood Gene Expression Pattern Through Tuberculosis Treatment Reflect Modulation of the Humoral Immune Response

(2012) Jacqueline M. Cliff et al.   JOURNAL OF INFECTIOUS DISEASES

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

(2012) Chloe I. Bloom et al.   PLoS One

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

Increased Interferon Alpha Expression in Circulating Plasmacytoid Dendritic Cells of HIV-1-Infected Patients

(2009) Clara Lehmann et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES