Side chain effect in the modulation of αvβ3/α5β1 integrin activity via clickable isoxazoline-RGD-mimetics: development of molecular delivery systems

GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin

(2019) Erpan Ahat et al.   MOLECULAR BIOLOGY OF THE CELL

Cyclic RGD peptidomimetics containing 4- and 5-amino-cyclopropane pipecolic acid (CPA) templates as dual αVβ3 and α5β1 integrin ligands

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New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities

(2016) Lucia Ferrazzano et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins

(2016) Monica Baiula et al.   JOURNAL OF MEDICINAL CHEMISTRY

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1Integrin by using Live-Cell NMR And Computational Studies

(2016) Ileana Guzzetti et al.   ChemistryOpen

Synthesis and Biological Evaluation of RGD Peptidomimetic-Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers

(2015) Alberto Dal Corso et al.   CHEMISTRY-A EUROPEAN JOURNAL

?v?3 Integrin-Targeted Peptide/Peptidomimetic-Drug Conjugates: In-Depth Analysis of the Linker Technology

(2015) Alberto Dal Corso et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Integrin traffic - the update

(2015) N. De Franceschi et al.   JOURNAL OF CELL SCIENCE

Enhancing cancer targeting and anticancer activity by a stimulus-sensitive multifunctional polymer-drug conjugate

(2015) Ying Tu et al.   JOURNAL OF CONTROLLED RELEASE

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

(2015) Madduri Srinivasarao et al.   NATURE REVIEWS DRUG DISCOVERY

Design, synthesis and antifungal activity of novel paeonol derivatives linked with 1,2,3-triazole moiety by the click reaction

(2015) Yuqin Jiang et al.   JOURNAL OF CHEMICAL RESEARCH

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives

(2014) Paola Galletti et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

Tumor Targeting via Integrin Ligands

(2013) Udaya Kiran Marelli et al.   Frontiers in Oncology

Antibody-Recruiting Molecules: An Emerging Paradigm for Engaging Immune Function in Treating Human Disease

(2012) Patrick J. McEnaney et al.   ACS Chemical Biology

Design, Synthesis, and Biological Evaluation of Novel cRGD–Paclitaxel Conjugates for Integrin-Assisted Drug Delivery

(2012) Michael Pilkington-Miksa et al.   BIOCONJUGATE CHEMISTRY

Camptothecins in tumor homing via an RGD sequence mimetic

(2012) Domenico Alloatti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain

(2012) V. H. Lobert et al.   JOURNAL OF CELL SCIENCE

Method for Assigning Structure of 1,2,3-Triazoles

(2012) Xavier Creary et al.   JOURNAL OF ORGANIC CHEMISTRY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Integrin Targeted Delivery of Chemotherapeutics

(2012) Kai Chen et al.   Theranostics

Development of Isoxazoline-Containing Peptidomimetics as Dual αvβ3 and α5β1 Integrin Ligands

(2011) Alessandra Tolomelli et al.   ChemMedChem

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress

(2011) Twan Lammers et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Delivery of Paclitaxel to Tumor Cells: Synthesis and in Vitro Evaluation

(2010) John M. Ndungu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Strain-Promoted Alkyne Azide Cycloaddition for the Functionalization of Poly(amide)-Based Dendrons and Dendrimers

(2010) Cátia Ornelas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Agonizing Integrin Antagonists?

(2009) Sara M. Weis et al.   CANCER CELL

A bright and photostable photoconvertible fluorescent protein

(2009) Sean A McKinney et al.   NATURE METHODS

Contribution of α4β1 integrin to the antiallergic effect of levocabastine

(2008) Ahmed R. Qasem et al.   BIOCHEMICAL PHARMACOLOGY

Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST

(2008) Andrea Bedini et al.   JOURNAL OF NEUROCHEMISTRY

Lewis Acid Induced Highly Regioselective Synthesis of a New Class of Substituted Isoxazolidines

(2008) Fides Benfatti et al.   SYNLETT