Aberrant expression of the COX2/PGE2 axis is induced by activation of the RAF/MEK/ERK pathway in BRAFV595E canine urothelial carcinoma

Assessment of Human Epidermal Growth Factor Receptor 2 Expression in Canine Urothelial Carcinoma of the Urinary Bladder

(2019) Masaya Tsuboi et al.   VETERINARY PATHOLOGY

Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial

(2019) Keisuke Kosumi et al.   EUROPEAN JOURNAL OF CANCER

Anti-tumor effects of the histone deacetylase inhibitor vorinostat on canine urothelial carcinoma cells

(2019) Shotaro Eto et al.   PLoS One

GREIN: An Interactive Web Platform for Re-analyzing GEO RNA-seq Data

(2019) Naim Al Mahi et al.   Scientific Reports

Overexpression of COX2 indicates poor survival in urothelial bladder cancer

(2018) Usha Agrawal et al.   Annals of Diagnostic Pathology

Comprehensive gene expression analysis of canine invasive urothelial bladder carcinoma by RNA-Seq

(2018) Shingo Maeda et al.   BMC CANCER

AZ304, a novel dual BRAF inhibitor, exerts anti-tumour effects in colorectal cancer independently of BRAF genetic status

(2018) Rui Ma et al.   BRITISH JOURNAL OF CANCER

Anti-tumour effect of lapatinib in canine transitional cell carcinoma cell lines

(2018) Kosei Sakai et al.   Veterinary and Comparative Oncology

Molecular investigation of the direct anti-tumour effects of nonsteroidal anti-inflammatory drugs in a panel of canine cancer cell lines

(2017) R. Yoshitake et al.   VETERINARY JOURNAL

Senescent tumor cells lead the collective invasion in thyroid cancer

(2017) Young Hwa Kim et al.   Nature Communications

ERK2 and JNK1 contribute to TNF-α-induced IL-8 expression in synovial fibroblasts

(2017) Shinichi Namba et al.   PLoS One

Negative feedback regulation of the ERK1/2 MAPK pathway

(2016) David Lake et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test

(2015) B. Decker et al.   MOLECULAR CANCER RESEARCH

Management of transitional cell carcinoma of the urinary bladder in dogs: A review

(2015) Christopher M. Fulkerson et al.   VETERINARY JOURNAL

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

(2014) S. Venderbosch et al.   CLINICAL CANCER RESEARCH

Differences in Expression of Uroplakin III, Cytokeratin 7, and Cyclooxygenase-2 in Canine Proliferative Urothelial Lesions of the Urinary Bladder

(2014) D. G. Sledge et al.   VETERINARY PATHOLOGY

Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor

(2013) T M Becker et al.   ONCOGENE

Wnt signaling potentiates nevogenesis

(2013) J. S. Pawlikowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRAFV600Eremodels the melanocyte transcriptome and inducesBANCRto regulate melanoma cell migration

(2012) Ross J. Flockhart et al.   GENOME RESEARCH

Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

(2012) Axel Hauschild et al.   LANCET

Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

(2012) John M. Kyriakis et al.   PHYSIOLOGICAL REVIEWS

COX2 overexpression is a prognostic marker for Stage III breast cancer

(2011) Hee Sung Kim et al.   BREAST CANCER RESEARCH AND TREATMENT

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Overexpression of cyclooxygenase-2 in NCI-H292 human alveolar epithelial carcinoma cells: Roles of p38 MAPK, ERK-1/2, and PI3K/PKB signaling proteins

(2011) Suhaeng Sung et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Signal pathways JNK and NF-κB, identified by global gene expression profiling, are involved in regulation of TNFα-induced mPGES-1 and COX-2 expression in gingival fibroblasts

(2010) Tove Båge et al.   BMC GENOMICS

COX-2 expression and outcome in canine nasal carcinomas treated with hypofractionated radiotherapy*†

(2010) Z. Belshaw et al.   Veterinary and Comparative Oncology

HGF/Met signalling promotes PGE2 biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells

(2009) A. E. Moore et al.   CARCINOGENESIS

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Oncogenic K-Ras Regulates Proliferation and Cell Junctions in Lung Epithelial Cells through Induction of Cyclooxygenase-2 and Activation of Metalloproteinase-9

(2008) Xue-Qing Wang et al.   MOLECULAR BIOLOGY OF THE CELL