CYP2J2 Modulates Diverse Transcriptional Programs in Adult Human Cardiomyocytes

Cytochrome P450 Structure, Function and Clinical Significance: A Review

(2018) Palrasu Manikandan et al.   CURRENT DRUG TARGETS

CYP2J2 Expression in Adult Ventricular Myocytes Protects Against Reactive Oxygen Species Toxicity

(2018) Eric A. Evangelista et al.   DRUG METABOLISM AND DISPOSITION

Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes

(2018) Theresa Aliwarga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease

(2018) Yue Zhao et al.   Scientific Reports

Genetic ablation or pharmacological inhibition of Kv1.1 potassium channel subunits impairs atrial repolarization in mice

(2018) Man Si et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Enzymatic and free radical formation of cis - and trans - epoxyeicosatrienoic acids in vitro and in vivo

(2017) Theresa Aliwarga et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver

(2017) Meijuan Xu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Long Noncoding RNA Kcna2 Antisense RNA Contributes to Ventricular Arrhythmias via Silencing Kcna2 in Rats With Congestive Heart Failure

(2017) Qing‐Qing Long et al.   Journal of the American Heart Association

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies

(2015) I El-Serafi et al.   PHARMACOGENOMICS JOURNAL

Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure

(2014) Yuko Yamada et al.   CARDIOVASCULAR RESEARCH

Sex differences in SR Ca2+ release in murine ventricular myocytes are regulated by the cAMP/PKA pathway

(2014) Randi J. Parks et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac-Specific Inhibition of Kinase Activity in Calcium/Calmodulin-Dependent Protein Kinase Kinase-β Leads to Accelerated Left Ventricular Remodeling and Heart Failure after Transverse Aortic Constriction in Mice

(2014) Shin Watanabe et al.   PLoS One

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis

(2014) J. Lauriol et al.   Science Signaling

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

FGF12 is a candidate Brugada syndrome locus

(2013) Jessica A. Hennessey et al.   HEART RHYTHM

CYP2J2 Overexpression Protects against Arrhythmia Susceptibility in Cardiac Hypertrophy

(2013) Christina Westphal et al.   PLoS One

Measuring and evaluating the role of ATP-sensitive K+ channels in cardiac muscle

(2012) Eirini Kefaloyianni et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transient outward current (Ito) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome

(2011) John R. Giudicessi et al.   HEART RHYTHM

Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

(2011) Norimichi Koitabashi et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolic Activity and mRNA Levels of Human Cardiac CYP450s Involved in Drug Metabolism

(2010) Veronique Michaud et al.   PLoS One

Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes

(2010) Jill E. Skepner et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity

(2009) Yunfang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis

(2009) Shiling Yang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Epoxyeicosatrienoic acids: formation, metabolism and potential role in tissue physiology and pathophysiology

(2009) Rüdiger Kaspera et al.   Expert Opinion on Drug Metabolism & Toxicology

Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450

(2008) Maude Fer et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION