Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies

Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation

(2014) Ibrahim El-Serafi et al.   PLoS One

The effects of fluorouracil, epirubicin, and cyclophosphamide (FEC60) on the intestinal barrier function and gut peptides in breast cancer patients: an observational study

(2013) Francesco Russo et al.   BMC CANCER

Cytochrome P450 2J2 is protective against global cerebral ischemia in transgenic mice

(2012) Rui Li et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases

(2011) Xizhen Xu et al.   ADVANCED DRUG DELIVERY REVIEWS

Pharmacokinetics of cyclophosphamide enantiomers in patients with breast cancer

(2011) Bruno José Dumêt Fernandes et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients

(2011) Nasir Ali Afsar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Gene Polymorphisms in Cyclophosphamide Metabolism Pathway,Treatment-Related Toxicity, and Disease-Free Survival in SWOG 8897 Clinical Trial for Breast Cancer

(2010) S. Yao et al.   CLINICAL CANCER RESEARCH

Cytochrome P450 2J2 Is Highly Expressed in Hematologic Malignant Diseases and Promotes Tumor Cell Growth

(2010) C. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Identification of Novel Substrates for Human Cytochrome P450 2J2

(2009) C. A. Lee et al.   DRUG METABOLISM AND DISPOSITION

Selective Inhibitors of CYP2J2 Related to Terfenadine Exhibit Strong Activity against Human Cancers in Vitro and in Vivo

(2009) C. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases

(2008) Richard K. Burt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Improvement of Cyclophosphamide Activation by CYP2B6 Mutants: From in Silico to ex Vivo

(2008) T.-A. Nguyen et al.   MOLECULAR PHARMACOLOGY

Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide

(2008) Corine Ekhart et al.   Pharmacogenetics and Genomics