A Two-Component Alkyne Metathesis Catalyst System with an Improved Substrate Scope and Functional Group Tolerance: Development and Applications to Natural Product Synthesis

Organocatalytic, Asymmetric Total Synthesis of (−)-Haliclonin A

(2016) Lian-Dong Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ring-closing metathesis in an enantioselective synthesis of the macrocyclic core of crassin acetate

(2016) Gunnar Herstad et al.   TETRAHEDRON

The Triple-Bond Metathesis of Aryldiazonium Salts: A Prospect for Dinitrogen Cleavage

(2015) Aaron D. Lackner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solution-Phase Dynamic Assembly of Permanently Interlocked Aryleneethynylene Cages through Alkyne Metathesis

(2015) Qi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective Formation of a Trisubstituted Alkene Motif bytrans-Hydrostannation/Stille Coupling: Application to the Total Synthesis and Late-Stage Modification of 5,6-Dihydrocineromycin B

(2015) Stephan M. Rummelt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembly of Disorazole C1through a One-Pot Alkyne Metathesis Homodimerization Strategy

(2015) Kevin J. Ralston et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Concise Total Synthesis of Enigmazole A

(2015) Andreas Ahlers et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A hydrogen bonded molecular capsule versus a 3D network of tripodal organopolysilanols

(2015) Marina Fukawa et al.   CHEMICAL COMMUNICATIONS

Total Synthesis, Stereochemical Revision, and Biological Reassessment of Mandelalide A: Chemical Mimicry of Intrafamily Relationships

(2015) Jens Willwacher et al.   CHEMISTRY-A EUROPEAN JOURNAL

Concise Total Synthesis of Ivorenolide B

(2015) Felix Ungeheuer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of an Exceptional Brominated 4-Pyrone Derivative of Algal Origin: An Exercise in Gold Catalysis and Alkyne Metathesis

(2015) Laura Hoffmeister et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Selective Homodimerization/Hydrogenation Strategy for Sequential Dicarba Bridge Formation

(2015) James Burnley et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Selective Molybdenum ONO Pincer Complex Initiates the Living Ring-Opening Metathesis Polymerization of Strained Alkynes with Exceptionally Low Polydispersity Indices

(2015) Donatela E. Bellone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Ivorenolide A Following a Base-Induced Elimination Protocol

(2015) Debendra K. Mohapatra et al.   ORGANIC LETTERS

Total Synthesis of the Biphenyl Alkaloid (−)-Lythranidine

(2014) Konrad Gebauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Tetrameric Cage withD2hSymmetry through Alkyne Metathesis

(2014) Qi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Practical Aerobic Oxidations of Alcohols and Amines with Homogeneous Copper/TEMPO and Related Catalyst Systems

(2014) Bradford L. Ryland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Formal Total Synthesis of Kendomycin by Way of Alkyne Metathesis/Gold Catalysis

(2014) Laura Hoffmeister et al.   CHEMISTRY-A EUROPEAN JOURNAL

A New Method for the Preparation of Non-Terminal Alkynes: Application to the Total Syntheses of Tulearin A and C

(2014) Konrad Lehr et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cross-Metathesis of Terminal Alkynes

(2014) Rudy Lhermet et al.   CHEMISTRY-A EUROPEAN JOURNAL

Concise Total Syntheses of Amphidinolides C and F

(2014) Gaëlle Valot et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxygenated Metabolites ofn-3 Polyunsaturated Fatty Acids as Potential Oxidative Stress Biomarkers: Total Synthesis of 8-F3t-IsoP, 10-F4t-NeuroP and [D4]-10-F4t-NeuroP

(2014) Alexandre Guy et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis, Molecular Editing, and Biological Assessment of the Potent Cytotoxin Leiodermatolide

(2014) Damien Mailhol et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicolor Live-Cell Chemical Imaging by Isotopically Edited Alkyne Vibrational Palette

(2014) Zhixing Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Relaxing Conformational Constraints in Dynamic Macrocycle Synthesis

(2014) Scott W. Sisco et al.   MACROMOLECULES

Ivorenolide B, an Immunosuppressive 17-Membered Macrolide from Khaya ivorensis: Structural Determination and Total Synthesis

(2014) Yao Wang et al.   ORGANIC LETTERS

Transannular reactions in asymmetric total synthesis

(2014) Efraím Reyes et al.   TETRAHEDRON

Multidentate Triphenolsilane-Based Alkyne Metathesis Catalysts

(2013) Haishen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

Total Synthesis of the Tubulin Inhibitor WF-1360F Based on Macrocycle Formation through Ring-Closing Alkyne Metathesis

(2013) Christian M. Neuhaus et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alcohol-Promoted Ring-Opening Alkyne Metathesis Polymerization

(2013) Daniel W. Paley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Amphidinolide F

(2013) Gaëlle Valot et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alkyne Metathesis on the Rise

(2013) Alois Fürstner   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Porous Poly(aryleneethynylene) Networks through Alkyne Metathesis

(2013) Youlong Zhu et al.   CHEMISTRY OF MATERIALS

Total Syntheses and Biological Reassessment of Lactimidomycin, Isomigrastatin and Congener Glutarimide Antibiotics

(2013) Kévin Micoine et al.   CHEMISTRY-A EUROPEAN JOURNAL

Increasing the Structural Span of Alkyne Metathesis

(2013) Peter Persich et al.   CHEMISTRY-A EUROPEAN JOURNAL

Formal Total Synthesis of the Algal Toxin (−)-Polycavernoside A

(2013) Lennart Brewitz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of Nominal Gobienine A

(2013) Azusa Kondoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Extracellular Signal-Regulated Kinases (ERK) Inhibitors from Aristolochia yunnanensis

(2013) Zhong-Bin Cheng et al.   JOURNAL OF NATURAL PRODUCTS

Teaching Metathesis "Simple" Stereochemistry

(2013) A. Furstner   SCIENCE

Total synthesis of the 2,6-disubstituted piperidine alkaloid (−)-andrachcinidine

(2013) Palakodety Radha Krishna et al.   TETRAHEDRON-ASYMMETRY

Solution processable polydiacetylenes (PDAs) through acyclic enediyne metathesis polymerization

(2013) Keda Hu et al.   Chemical Science

Homochiral Self-Sorting of BINOL Macrocycles

(2013) Scott W. Sisco et al.   Chemical Science

Highly Active Multidentate Alkyne Metathesis Catalysts: Ligand-Activity Relationship and Their Applications in Efficient Synthesis of Porphyrin-Based Aryleneethynylene Polymers

(2012) Kuthanapillil Jyothish et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Metathesis of Conjugated Diynes

(2012) Sergej Lysenko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Neurymenolide A Based on a Gold-Catalyzed Synthesis of 4-Hydroxy-2-pyrones

(2012) Wojciech Chaładaj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Divergent Total Synthesis of the Antimitotic Agent Leiodermatolide

(2012) Jens Willwacher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Suzuki reactions of extended scope: the ‘9-MeO-9-BBN variant’ as a complementary format for cross-coupling

(2012) Günter Seidel et al.   CHEMICAL COMMUNICATIONS

Optimized Synthesis, Structural Investigations, Ligand Tuning and Synthetic Evaluation of Silyloxy-Based Alkyne Metathesis Catalysts

(2012) Johannes Heppekausen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Biomimetic Total Synthesis of Cruentaren A via Aromatization of Diketodioxinones

(2012) Marianne Fouché et al.   JOURNAL OF ORGANIC CHEMISTRY

Directional Cyclooligomers via Alkyne Metathesis

(2012) Scott W. Sisco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ivorenolide A, an Unprecedented Immunosuppressive Macrolide from Khaya ivorensis: Structural Elucidation and Bioinspired Total Synthesis

(2012) Bo Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New ONO3- Trianionic Pincer-Type Ligand for Generating Highly Nucleophilic Metal–Carbon Multiple Bonds

(2012) Matthew E. O’Reilly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atom-Economical Synthesis of Functionalized Cycloalkanes via Catalytic Redox Cycloisomerization of Propargyl Alcohols

(2012) Barry M. Trost et al.   ORGANIC LETTERS

Transition-Metal-Catalyzed Functionalization of Propargylic Alcohols and Their Derivatives

(2012) Eike Bauer   SYNTHESIS-STUTTGART

Introducing A Podand Motif to Alkyne Metathesis Catalyst Design: A Highly Active Multidentate Molybdenum(VI) Catalyst that Resists Alkyne Polymerization

(2011) Kuthanapillil Jyothish et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Second-Generation Total Synthesis of Spirastrellolide F Methyl Ester: The Alkyne Route

(2011) Stefan Benson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Tulearin C

(2011) Konrad Lehr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metathesis in total synthesis

(2011) Alois Fürstner   CHEMICAL COMMUNICATIONS

Engineering Solid-State Morphologies in Carbazole–Ethynylene Macrocycles

(2011) Aaron D. Finke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Propargyl Alcohols as β-Oxocarbenoid Precursors for the Ruthenium-Catalyzed Cyclopropanation of Unactivated Olefins by Redox Isomerization

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Asymmetric Aminoallylation of Aldehydes: Synergism of Chiral and Nonchiral Brønsted Acids

(2011) Hong Ren et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis-Based and Protecting-Group-Free Total Syntheses of the Marine Oxylipins Hybridalactone and the Ecklonialactones A, B, and C

(2011) Volker Hickmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Practical Copper(I)/TEMPO Catalyst System for Chemoselective Aerobic Oxidation of Primary Alcohols

(2011) Jessica M. Hoover et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From Highly Enantioselective Catalytic Reaction of 1,3-Diynes with Aldehydes to Facile Asymmetric Synthesis of Polycyclic Compounds

(2011) Mark Turlington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereoselective Control of Intramolecular Aza-Michael Reactions Using Achiral Catalysts

(2011) Cheng Zhong et al.   ORGANIC LETTERS

Total Synthesis of (±)-Haliclonacyclamine C

(2010) Brian J. Smith et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Sulfinyl Amines as a Nitrogen Source in the Asymmetric Intramolecular Aza-Michael Reaction: Total Synthesis of (−)-Pinidinol

(2010) Santos Fustero et al.   CHEMISTRY-A EUROPEAN JOURNAL

Concise Total Synthesis of the Potent Translation and Cell Migration Inhibitor Lactimidomycin

(2010) Kevin Micoine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Practical New Silyloxy-Based Alkyne Metathesis Catalysts with Optimized Activity and Selectivity Profiles

(2010) Johannes Heppekausen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Substrate-Induced Covalent Assembly of a Chemzyme and Crystallographic Characterization of a Chemzyme−Substrate Complex

(2010) Gang Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective ProPhenol-Catalyzed Addition of 1,3-Diynes to Aldehydes to Generate Synthetically Versatile Building Blocks and Diyne Natural Products

(2010) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (−)-Nakadomarin A

(2010) Mark G. Nilson et al.   ORGANIC LETTERS

An Atom-Economical Access to β-Heteroarylated Ketones from Propargylic Alcohols via Tandem Ruthenium/Indium Catalysis

(2010) Barry M. Trost et al.   ORGANIC LETTERS

Dialkylbiaryl phosphines in Pd-catalyzed amination: a user's guide

(2010) David S. Surry et al.   Chemical Science

Tandem Ruthenium-Catalyzed Redox Isomerization−O-Conjugate Addition: An Atom-Economic Synthesis of Cyclic Ethers

(2009) Barry M. Trost et al.   ORGANIC LETTERS

Transannulation Reactions in the Synthesis of Natural Products

(2009) Paul Clarke et al.   SYNTHESIS-STUTTGART

Asymmetric synthesis of aza-diospongin A as an iNOS inducer

(2009) S. Chandrasekhar et al.   TETRAHEDRON-ASYMMETRY

An Atom-Economic and Selective Ruthenium-Catalyzed Redox Isomerization of Propargylic Alcohols. An Efficient Strategy for the Synthesis of Leukotrienes

(2008) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Ruthenium-Catalyzed, Atom-Economical Synthesis of Nitrogen Heterocycles

(2008) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of cleomiscosin C via a regioselective cycloaddition reaction of o-quinone

(2008) Atsuhito Kuboki et al.   TETRAHEDRON LETTERS