Increased EZH2 Levels in Anterior Cingulate Cortex Microglia Aggravate Neuropathic Pain by Inhibiting Autophagy Following Brachial Plexus Avulsion in Rats

LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing

(2019) Coralie Brifault et al.   GLIA

miR-101-3p induces autophagy in endometrial carcinoma cells by targeting EZH2

(2018) Cuilan Wang et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

MiR-124 induces autophagy-related cell death in cholangiocarcinoma cells through direct targeting of the EZH2–STAT3 signaling axis

(2018) Jun Ma et al.   EXPERIMENTAL CELL RESEARCH

Macrophage/microglial Ezh2 facilitates autoimmune inflammation through inhibition of Socs3

(2018) Xingli Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epigenetic Modifications Associated to Neuroinflammation and Neuropathic Pain After Neural Trauma

(2018) Clara Penas et al.   Frontiers in Cellular Neuroscience

Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex

(2018) Tao Chen et al.   Nature Communications

Environmental enrichment reduces adolescent anxiety- and depression-like behaviors of rats subjected to infant nerve injury

(2018) Xingrui Gong et al.   Journal of Neuroinflammation

MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12

(2018) Wei-Shiung Lian et al.   Cell Death & Disease

miR-124-3p attenuates neuropathic pain induced by chronic sciatic nerve injury in rats via targeting EZH2

(2018) Yang Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Suberoylanilide Hydroxamic Acid Triggers Autophagy by Influencing the mTOR Pathway in the Spinal Dorsal Horn in a Rat Neuropathic Pain Model

(2018) Xiang-Lan Feng et al.   NEUROCHEMICAL RESEARCH

The Changes of Intrinsic Excitability of Pyramidal Neurons in Anterior Cingulate Cortex in Neuropathic Pain

(2018) Zhilai Yang et al.   Frontiers in Cellular Neuroscience

Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages

(2017) Norikazu Kiguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2

(2017) Peilong Li et al.   MOLECULAR CANCER THERAPEUTICS

Fascin-1 Contributes to Neuropathic Pain by Promoting Inflammation in Rat Spinal Cord

(2017) Binbin Wang et al.   NEUROCHEMICAL RESEARCH

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

EZH2 regulates spinal neuroinflammation in rats with neuropathic pain

(2017) Ruchi Yadav et al.   NEUROSCIENCE

Modulation of Pain and Itch by Spinal Glia

(2017) Makoto Tsuda   Neuroscience Bulletin

Fuse-binding protein 1 is a target of the EZH2 inhibitor GSK343, in osteosarcoma cells

(2016) Xifeng Xiong et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

LncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2

(2016) Xin Wang et al.   Journal of Translational Medicine

Pain regulation by non-neuronal cells and inflammation

(2016) R.-R. Ji et al.   SCIENCE

Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells

(2016) Yizhou Yao et al.   Genes

Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway

(2015) Fu-Zheng Wei et al.   Autophagy

Neuropathic pain after brachial plexus avulsion - central and peripheral mechanisms

(2015) Manoel Jacobsen Teixeira et al.   BMC Neurology

A new rat model of neuropathic pain: Complete brachial plexus avulsion

(2015) Le Wang et al.   NEUROSCIENCE LETTERS

Increased autophagic activity in dorsal root ganglion attenuates neuropathic pain following peripheral nerve injury

(2015) Jian-Shuang Guo et al.   NEUROSCIENCE LETTERS

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer

(2015) Dejie Wang et al.   Oncotarget

Expression of LC3 and Beclin 1 in the spinal dorsal horn following spinal nerve ligation-induced neuropathic pain

(2013) Enji Zhang et al.   BRAIN RESEARCH

Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury

(2013) Guodong Shi et al.   GLIA

A new definition of neuropathic pain

(2011) Troels S. Jensen et al.   PAIN

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Microglial/macrophage GRK2 determines duration of peripheral IL-1β-induced hyperalgesia: Contribution of spinal cord CX3CR1, p38 and IL-1 signaling

(2010) Hanneke L.D.M. Willemen et al.   PAIN

From the neuromatrix to the pain matrix (and back)

(2010) G. D. Iannetti et al.   EXPERIMENTAL BRAIN RESEARCH

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL