Rac1 activates non-oxidative pentose phosphate pathway to induce chemoresistance of breast cancer
Published 2020 View Full Article
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Title
Rac1 activates non-oxidative pentose phosphate pathway to induce chemoresistance of breast cancer
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-03-19
DOI
10.1038/s41467-020-15308-7
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Note: Only part of the references are listed.- CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
- (2018) Shicheng Su et al. CELL
- Breast Cancer, Version 4.2017, NCCN Clinical Practice Guidelines in Oncology
- (2018) William J. Gradishar et al. Journal of the National Comprehensive Cancer Network
- Rho GTPases as therapeutic targets in cancer (Review)
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- Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine
- (2017) Chiranjib Chakraborty et al. Molecular Therapy-Nucleic Acids
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- (2016) Xiaoding Xu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- The Emerging Hallmarks of Cancer Metabolism
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- Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity
- (2016) Nathan G. Hedrick et al. NATURE
- Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion
- (2016) Ashish Juvekar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor growth accelerated by chemotherapy-induced senescent cells is suppressed by treatment with IL-12 producing cellular vaccines
- (2016) Jana Simova et al. Oncotarget
- Clinical experiences with systemically administered siRNA-based therapeutics in cancer
- (2015) Jonathan E. Zuckerman et al. NATURE REVIEWS DRUG DISCOVERY
- Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment
- (2015) Xi Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells
- (2014) S. W. Hofbauer et al. BLOOD
- Molecular Pathways: Targeting RAC-p21-Activated Serine-Threonine Kinase Signaling in RAS-Driven Cancers
- (2014) N. M. Baker et al. CLINICAL CANCER RESEARCH
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
- (2013) Nicolas Bertrand et al. ADVANCED DRUG DELIVERY REVIEWS
- Chemotherapy induced DNA damage response
- (2013) Derek Woods et al. CANCER BIOLOGY & THERAPY
- RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms
- (2013) Ralph Fritsch et al. CELL
- DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology
- (2013) Kahlin Cheung-Ong et al. CHEMISTRY & BIOLOGY
- RAC1: An Emerging Therapeutic Option for Targeting Cancer Angiogenesis and Metastasis
- (2013) H. K. Bid et al. MOLECULAR CANCER THERAPEUTICS
- PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1
- (2013) H. Ebi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug
- (2013) X. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RAC1P29S is a spontaneously activating cancer-associated GTPase
- (2013) M. J. Davis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- αVβ3 Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug
- (2012) Nora Graf et al. ACS Nano
- Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery
- (2011) Haijun Yu et al. ACS Nano
- Tunable, Ultrasensitive pH-Responsive Nanoparticles Targeting Specific Endocytic Organelles in Living Cells
- (2011) Kejin Zhou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- Role of Rho GTPases and their regulators in cancer progression
- (2011) Rajamani Rathinam Frontiers in Bioscience-Landmark
- Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
- (2010) Katrin Knop et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
- (2010) Mark E. Davis et al. NATURE
- Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes
- (2009) You-Yeon Won et al. JOURNAL OF CONTROLLED RELEASE
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
- (2008) E.A. Eisenhauer et al. EUROPEAN JOURNAL OF CANCER
- Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles
- (2008) S. Dhar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Critical Role for Rac1 in Tumor Progression of Human Colorectal Adenocarcinoma Cells
- (2007) Carolina Espina et al. AMERICAN JOURNAL OF PATHOLOGY
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