Ripasudil alleviated the inflammation of RPE cells by targeting the miR-136-5p/ROCK/NLRP3 pathway

Proline mediates metabolic communication between retinal pigment epithelial cells and the retina

(2019) Michelle Yam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

(2018) Wei Zhou et al.   KOREAN JOURNAL OF PARASITOLOGY

Ripasudil Attenuates Lipopolysaccharide (LPS)-Mediated Apoptosis and Inflammation in Pulmonary Microvascular Endothelial Cells via ROCK2/eNOS Signaling

(2018) Jianxin Yang et al.   MEDICAL SCIENCE MONITOR

LncRNA SNHG14 promotes inflammatory response induced by cerebral ischemia/reperfusion injury through regulating miR-136-5p /ROCK1

(2018) Yu Zhong et al.   CANCER GENE THERAPY

Additive intraocular pressure-lowering effects of the Rho kinase inhibitor ripasudil in Japanese patients with various subtypes of glaucoma

(2018) Takashi Komizo et al.   JAPANESE JOURNAL OF OPHTHALMOLOGY

Comparison of intraocular pressure-lowering effects of ripasudil hydrochloride hydrate for inflammatory and corticosteroid-induced ocular hypertension

(2017) Mami Yasuda et al.   PLoS One

Transcription Factor NF-κB: An Update on Intervention Strategies

(2016) Arvind Panday et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration

(2015) Souska Zandi et al.   Cell Reports

Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration

(2015) Monte J. Radeke et al.   Genome Medicine

Apoptosis-Associated Speck-like Protein Containing a CARD Forms Specks but Does Not Activate Caspase-1 in the Absence of NLRP3 during Macrophage Swelling

(2015) Vincent Compan et al.   JOURNAL OF IMMUNOLOGY

The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes

(2014) Sanae Kanno et al.   ARCHIVES OF TOXICOLOGY

Ripasudil: First Global Approval

(2014) Karly P. Garnock-Jones   DRUGS

Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages

(2013) Qiang Wang et al.   INTERNATIONAL IMMUNOLOGY

Elevated Levels of RhoA in the Optic Nerve Head of Human Eyes With Glaucoma

(2012) Brian Goldhagen et al.   JOURNAL OF GLAUCOMA