Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Activated Drp1-mediated mitochondrial ROS influence the gut microbiome and intestinal barrier after hemorrhagic shock

(2020) Chenyang Duan et al.   Aging-US

miRNA-mRNA crosstalk in myocardial ischemia induced by calcified aortic valve stenosis

(2019) Chenyang Duan et al.   Aging-US

Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism

(2019) Xiawei Cheng et al.   MOLECULAR CELL

Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone

(2019) Jia-Hau Yen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells

(2019) Elikanah Olusayo Adegoke et al.   JOURNAL OF APPLIED TOXICOLOGY

Comparative evaluation of conventional and novel extracts of stem bark of Terminalia arjuna for antihypertensive activity in BSO induced oxidative stress based rat model

(2019) Sarita Khatkar et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Reactive oxygen species-responsive nanoprodrug with quinone methides-mediated GSH depletion for improved chlorambucil breast cancers therapy

(2018) Cheng-Qiong Luo et al.   JOURNAL OF CONTROLLED RELEASE

Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling

(2018) Zhidan Chen et al.   Theranostics

Antioxidant and reactive oxygen species scavenging properties of cellular albumin in HepG2 cells is mediated by the glutathione redox system

(2018) Ali Seidkhani-Nahal et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Mitochondrial Division Inhibitor 1 Prevents Early-Stage Induction of Mitophagy and Accelerated Cell Death in a Rat Model of Moderate Controlled Cortical Impact Brain Injury

(2018) Fei Niu et al.   World Neurosurgery

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Drp1 regulates mitochondrial morphology and cell proliferation in cutaneous squamous cell carcinoma

(2017) Shinya Kitamura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension

(2017) Lian Tian et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Glucose Metabolism in Cancer and Ischemia: Possible Therapeutic Consequences of the Warburg Effect

(2017) Spela Salamon et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Prognostic role of tumorPIK3CAmutation in colorectal cancer: a systematic review and meta-analysis

(2016) Z. B. Mei et al.   ANNALS OF ONCOLOGY

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

(2016) K. Atkins et al.   CLINICAL SCIENCE

Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis

(2016) Hongli Hu et al.   HEPATOLOGY

Principal component analysis: a review and recent developments

(2016) Ian T. Jolliffe et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

The divergent roles of autophagy in ischemia and preconditioning

(2015) Rui Sheng et al.   ACTA PHARMACOLOGICA SINICA

A phosphorescent rhenium(i) histone deacetylase inhibitor: mitochondrial targeting and paraptosis induction

(2015) Rui-Rong Ye et al.   CHEMICAL COMMUNICATIONS

Effect of limited ischemia time on the amount and function of mitochondria within human skeletal muscle cells

(2015) A. Jawhar et al.   European Journal of Trauma and Emergency Surgery

Acupuncture reduced apoptosis and up-regulated BDNF and GDNF expression in hippocampus following hypoxia–ischemia in neonatal rats

(2015) Yong Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Beneficial effect of cyclosporine A on traumatic hemorrhagic shock

(2015) Yan Lei et al.   JOURNAL OF SURGICAL RESEARCH

Mitochondrial control by DRP1 in brain tumor initiating cells

(2015) Qi Xie et al.   NATURE NEUROSCIENCE

Advances in Vascular Hyporeactivity After Shock

(2015) Chenyang Duan et al.   SHOCK

Activation of sirtuin 1/3 improves vascular hyporeactivity in severe hemorrhagic shock by alleviation of mitochondrial damage

(2015) Pengyun Li et al.   Oncotarget

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance

(2014) Lori Buhlman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

(2014) Scott A. Soleimanpour et al.   CELL

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition

(2013) D.Y. Xia et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice

(2013) W.-L. Li et al.   NEUROSCIENCE

Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-κB/p53 signaling pathway

(2013) D.R. Cui et al.   NEUROSCIENCE

Effects of the Balance in Activity of RhoA and Rac1 on the Shock-Induced Biphasic Change of Vascular Reactivity in Rats

(2011) Tao Li et al.   ANNALS OF SURGERY

Paneth cell-derived interleukin-17A causes multiorgan dysfunction after hepatic ischemia and reperfusion injury

(2011) Sang Won Park et al.   HEPATOLOGY

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation

(2011) S. Carloni et al.   NEUROSCIENCE

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia

(2010) Ai-Ping Qin et al.   Autophagy

Enhancement of Autophagic Flux after Neonatal Cerebral Hypoxia-Ischemia and Its Region-Specific Relationship to Apoptotic Mechanisms

(2009) Vanessa Ginet et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in hypoxia-ischemia induced brain injury: Evidences and speculations

(2009) Walter Balduini et al.   Autophagy

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart

(2008) Edward J. Miller et al.   NATURE

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE