MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling

MOB (Mps one Binder) Proteins in the Hippo Pathway and Cancer

(2019) Gundogdu et al.   Cells

Glioma infiltration and extracellular matrix: key players and modulators

(2018) Valéria Pereira Ferrer et al.   GLIA

Depression promotes prostate cancer invasion and metastasis via a sympathetic-cAMP-FAK signaling pathway

(2018) Yan Cheng et al.   ONCOGENE

Ajuba inhibits hepatocellular carcinoma cell growth via targeting of β-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation

(2018) Min Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Current and future strategies for treatment of glioma

(2016) Nancy Ann Oberheim Bush et al.   NEUROSURGICAL REVIEW

Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling

(2016) Paul M Daniel et al.   Cell Death & Disease

Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

(2015) Ksenya Shchors et al.   CANCER CELL

Regulation of DNA damage responses and cell cycle progression by hMOB2

(2015) Valenti Gomez et al.   CELLULAR SIGNALLING

JAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma

(2014) Q. Zheng et al.   NEURO-ONCOLOGY

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

Mps one binder 2 gene upregulation in the stellation of astrocytes induced by cAMP-dependent pathway

(2012) Kuan-Min Fang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

MOB control: Reviewing a conserved family of kinase regulators

(2011) Alexander Hergovich   CELLULAR SIGNALLING

The promotion of neurite formation in Neuro2A cells by mouse Mob2 protein

(2011) Cheng-Han Lin et al.   FEBS LETTERS

Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells

(2011) Naotoshi Sugimoto et al.   NEUROSCIENCE LETTERS

Epac: Defining a New Mechanism for cAMP Action

(2010) Martijn Gloerich et al.   Annual Review of Pharmacology and Toxicology

The effect of epidermal growth factor receptor variant III on glioma cell migration by stimulating ERK phosphorylation through the focal adhesion kinase signaling pathway

(2010) Mingzhu Liu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Tricyclic antidepressants and the incidence of certain cancers: a study using the GPRD

(2010) A J Walker et al.   BRITISH JOURNAL OF CANCER

Cyclic AMP Suppression Is Sufficient to Induce Gliomagenesis in a Mouse Model of Neurofibromatosis-1

(2010) N. M. Warrington et al.   CANCER RESEARCH

Defective cAMP Generation Underlies the Sensitivity of CNS Neurons to Neurofibromatosis-1 Heterozygosity

(2010) J. A. Brown et al.   JOURNAL OF NEUROSCIENCE

Differential NDR/LATS Interactions with the Human MOB Family Reveal a Negative Role for Human MOB2 in the Regulation of Human NDR Kinases

(2010) R. S. Kohler et al.   MOLECULAR AND CELLULAR BIOLOGY

Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in human gliomas is associated with unfavorable overall survival

(2010) Lianshu Ding et al.   Translational Research

Signal transduction by focal adhesion kinase in cancer

(2009) Jihe Zhao et al.   CANCER AND METASTASIS REVIEWS

cAMP Inhibits Cell Migration by Interfering with Rac-induced Lamellipodium Formation

(2008) Lin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion

(2008) Sebastian Seufert et al.   PPAR Research

Regulating gene transcription in response to cyclic AMP elevation

(2007) William A. Sands et al.   CELLULAR SIGNALLING