Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling

Epidermal growth factor receptor targeting and challenges in glioblastoma

(2016) Amy Haseley Thorne et al.   NEURO-ONCOLOGY

Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

(2015) Ksenya Shchors et al.   CANCER CELL

A randomised, open label phase III trial with nimotuzumab, an anti-epidermal growth factor receptor monoclonal antibody in the treatment of newly diagnosed adult glioblastoma

(2015) Manfred Westphal et al.   EUROPEAN JOURNAL OF CANCER

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme

(2015) Daniel V. Brown et al.   Oncotarget

Age related changes of cAMP and MAPK signaling in Leydig cells of Wistar rats

(2014) S.J. Sokanovic et al.   EXPERIMENTAL GERONTOLOGY

Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance

(2014) Hariharan Easwaran et al.   MOLECULAR CELL

Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies

(2014) Chong Sun et al.   TRENDS IN BIOCHEMICAL SCIENCES

Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation

(2014) P Daniel et al.   Oncogenesis

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry

(2013) Svetlana N Popova et al.   HISTOPATHOLOGY

Murine cell line model of proneural glioma for evaluation of anti-tumor therapies

(2013) Adam M. Sonabend et al.   JOURNAL OF NEURO-ONCOLOGY

Tumour heterogeneity in the clinic

(2013) Philippe L. Bedard et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The Tumor Suppressor PTEN Is Exported in Exosomes and Has Phosphatase Activity in Recipient Cells

(2012) U. Putz et al.   Science Signaling

Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messenger

(2011) P. A. Insel et al.   Acta Physiologica

The MEK-ERK pathway negatively regulates bim expression through the 3' UTR in sympathetic neurons

(2011) Rosie Hughes et al.   BMC NEUROSCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

ERK and PDE4 cooperate to induce RAF isoform switching in melanoma

(2011) Amélie Marquette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cyclic AMP Suppression Is Sufficient to Induce Gliomagenesis in a Mouse Model of Neurofibromatosis-1

(2010) N. M. Warrington et al.   CANCER RESEARCH

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

(2010) Diane Moujalled et al.   EMBO REPORTS

Colorectal cancer risk in relation to antidepressant medication use

(2010) Jessica Chubak et al.   INTERNATIONAL JOURNAL OF CANCER

Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme

(2009) David M. Peereboom et al.   JOURNAL OF NEURO-ONCOLOGY

Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research

(2009) S. Madhavan et al.   MOLECULAR CANCER RESEARCH