Targeted Pathway-based In Vivo Testing Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model Amphibian Xenopus laevis

Development of a non-radioactive screening assay to detect chemicals disrupting the human sodium iodide symporter activity

(2019) Hongyan Dong et al.   TOXICOLOGY IN VITRO

Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches

(2019) Pamela D. Noyes et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library

(2019) Katie Paul-Friedman et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening

(2019) Chad Deisenroth et al.   TOXICOLOGICAL SCIENCES

High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library

(2018) Jun Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases

(2018) Jennifer H Olker et al.   TOXICOLOGICAL SCIENCES

Frogs model man:In vivothyroid hormone signaling during development

(2017) Laurent M. Sachs et al.   GENESIS

Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework

(2017) Iman Hassan et al.   TOXICOLOGICAL SCIENCES

Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity

(2017) Michael W Hornung et al.   TOXICOLOGICAL SCIENCES

Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)

(2017) Daniel R. Hallinger et al.   TOXICOLOGY IN VITRO

Identifying reference chemicals for thyroid bioactivity screening

(2016) Susanna Wegner et al.   REPRODUCTIVE TOXICOLOGY

Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries

(2016) Katie Paul Friedman et al.   TOXICOLOGICAL SCIENCES

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure

(2015) Imran Shah et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

In Vitro,Ex Vivo, andIn VivoDetermination of Thyroid Hormone Modulating Activity of Benzothiazoles

(2015) Michael W. Hornung et al.   TOXICOLOGICAL SCIENCES

Development of a Thyroperoxidase Inhibition Assay for High-Throughput Screening

(2014) Katie B. Paul et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Corrosion inhibition of carbon steel immersed in a 1M HCl solution using benzothiazole derivatives

(2014) Hojat Jafari et al.   Arabian Journal of Chemistry

Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat

(2013) Katie B. Paul et al.   TOXICOLOGY

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

(2013) AlberTinka J. Murk et al.   TOXICOLOGY IN VITRO

Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole

(2012) Joseph E. Tietge et al.   AQUATIC TOXICOLOGY

Control of pituitary thyroid-stimulating hormone synthesis and secretion by thyroid hormones during Xenopus metamorphosis

(2011) Robin M. Sternberg et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Developmental thyroid hormone disruption: Prevalence, environmental contaminants and neurodevelopmental consequences

(2011) Mary E. Gilbert et al.   NEUROTOXICOLOGY

Impact of Low-Level Thyroid Hormone Disruption Induced by Propylthiouracil on Brain Development and Function

(2011) Mary E. Gilbert   TOXICOLOGICAL SCIENCES

Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis

(2010) Joseph E. Tietge et al.   AQUATIC TOXICOLOGY

Evaluation of the amphibian metamorphosis assay: Exposure to the goitrogen methimazole and the endogenous thyroid hormone L-thyroxine

(2010) Katherine Coady et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Approximate Bayesian inference for latent Gaussian models by using integrated nested Laplace approximations

(2009) Håvard Rue et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Xenopus laevis as a model for studying thyroid hormone signalling: From development to metamorphosis

(2008) Ghislaine Morvan-Dubois et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Factors Influencing the Study of Peroxidase-Generated Iodine Species and Implications for Thyroglobulin Synthesis

(2008) Jack Kessler et al.   THYROID

Developmental neurotoxicity of Propylthiouracil (PTU) in rats: Relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes

(2008) Marta Axelstad et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY