Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

(2019) Jamie N. Justice et al.   EBioMedicine

Engineering Approaches to Study Cellular Decision Making

(2018) Pamela K. Kreeger et al.   Annual Review of Biomedical Engineering

Senolytics improve physical function and increase lifespan in old age

(2018) Ming Xu et al.   NATURE MEDICINE

The Role of the Immune Cells in Fracture Healing

(2018) Gurpreet S. Baht et al.   Current Osteoporosis Reports

The Conventional Nature of Non-MHC-Restricted T Cells

(2018) Marco Lepore et al.   Frontiers in Immunology

Macrophage response to hydrophilic biomaterials regulates MSC recruitment and T-helper cell populations

(2018) Kelly M. Hotchkiss et al.   BIOMATERIALS

US FDA Breast Implant Postapproval Studies

(2018) Christopher J. Coroneos et al.   ANNALS OF SURGERY

Divergent immune responses to synthetic and biological scaffolds

(2018) Kaitlyn Sadtler et al.   BIOMATERIALS

IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis

(2017) Ellyse Cipolla et al.   FASEB JOURNAL

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

(2017) Birgit Ritschka et al.   GENES & DEVELOPMENT

Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates

(2017) Joshua C. Doloff et al.   NATURE MATERIALS

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

(2017) Ok Hee Jeon et al.   NATURE MEDICINE

Radiation-Induced Dermatitis is Mediated by IL17-Expressing γδ T Cells

(2017) Wupeng Liao et al.   RADIATION RESEARCH

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis

(2017) David Lagares et al.   Science Translational Medicine

Cellular senescence mediates fibrotic pulmonary disease

(2017) Marissa J. Schafer et al.   Nature Communications

Cellular Senescence: A Translational Perspective

(2017) James L. Kirkland et al.   EBioMedicine

Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation

(2016) Peng Zhang et al.   JOURNAL OF CONTROLLED RELEASE

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

(2016) K. Sadtler et al.   SCIENCE

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity

(2015) Allyson K. Palmer et al.   DIABETES

The 3 major types of innate and adaptive cell-mediated effector immunity

(2015) Francesco Annunziato et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

Biomaterial Hypersensitivity: Is It Real? Supportive Evidence and Approach Considerations for Metal Allergic Patients following Total Knee Arthroplasty

(2015) Andrew J. Mitchelson et al.   Biomed Research International

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

Mechanotransduction and fibrosis

(2014) Dominik Duscher et al.   JOURNAL OF BIOMECHANICS

Cardiac fibroblasts mediate IL-17A–driven inflammatory dilated cardiomyopathy

(2014) Lei Wu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Breast Implant–Associated Anaplastic Large Cell Lymphoma: Report of 2 Cases and Review of the Literature

(2014) Alexandra M. Hart et al.   Aesthetic Surgery Journal

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Polypropylene surgical mesh coated with extracellular matrix mitigates the host foreign body response

(2013) Matthew T. Wolf et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

A senescent cell bystander effect: senescence-induced senescence

(2012) Glyn Nelson et al.   AGING CELL

Cytokine mediated tissue fibrosis

(2012) Lee A. Borthwick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents

(2012) Ricardo P Garay et al.   Expert Opinion on Drug Delivery

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

(2012) Fanli Meng et al.   GASTROENTEROLOGY

Activation of the Inflammasome and Enhanced Migration of Microparticle-Stimulated Dendritic Cells to the Draining Lymph Node

(2012) Ismail M. Meraz et al.   MOLECULAR PHARMACEUTICS

T Regulatory Cells and TH17 Cells in Peri–Silicone Implant Capsular Fibrosis

(2012) Dolores Wolfram et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

A Murine Model of Volumetric Muscle Loss and a Regenerative Medicine Approach for Tissue Replacement

(2012) Brian M. Sicari et al.   TISSUE ENGINEERING PART A

Systemic Inflammatory Reaction After Silicone Breast Implant

(2011) Maira M. Silva et al.   AESTHETIC PLASTIC SURGERY

Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1-Dependent and -Independent Mechanisms

(2011) S. Mi et al.   JOURNAL OF IMMUNOLOGY

Biocompatibility of implants: lymphocyte/macrophage interactions

(2011) James M. Anderson et al.   Seminars in Immunopathology

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

(2010) Mark S. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

B cells contribute to ischemia/reperfusion-mediated tissue injury

(2009) Jie Chen et al.   JOURNAL OF AUTOIMMUNITY

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY