Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome

Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase

(2019) Clémence Richetta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unintegrated HIV-1 DNAs are loaded with core and linker histones and transcriptionally silenced

(2019) Franziska K. Geis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

(2018) Ashwanth C. Francis et al.   Cell Host & Microbe

Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration

(2018) Vasudevan Achuthan et al.   Cell Host & Microbe

NP220 mediates silencing of unintegrated retroviral DNA

(2018) Yiping Zhu et al.   NATURE

Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry

(2016) Gary Z. Wang et al.   Cell Host & Microbe

Nuclear landscape of HIV-1 infection and integration

(2016) Marina Lusic et al.   NATURE REVIEWS MICROBIOLOGY

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

(2016) Gregory A. Sowd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear architecture dictates HIV-1 integration site selection

(2015) Bruna Marini et al.   NATURE

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z

(2014) Zhuo Mao et al.   CELL RESEARCH

ANP32E is a histone chaperone that removes H2A.Z from chromatin

(2014) Arnaud Obri et al.   NATURE

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

(2014) Akash Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone variants at the transcription start-site

(2014) Tatiana A. Soboleva et al.   TRENDS IN GENETICS

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes

(2014) Bernd Stadelmayer et al.   Nature Communications

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2

(2013) Naoki Horikoshi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Control of Transcriptional Elongation

(2013) Hojoong Kwak et al.   Annual Review of Genetics

Nucleosome-free Region Dominates Histone Acetylation in Targeting SWR1 to Promoters for H2A.Z Replacement

(2013) Anand Ranjan et al.   CELL

SWR-C and INO80 Chromatin Remodelers Recognize Nucleosome-free Regions Near +1 Nucleosomes

(2013) Kuangyu Yen et al.   CELL

Negative Elongation Factor (NELF) Coordinates RNA Polymerase II Pausing, Premature Termination, and Chromatin Remodeling to Regulate HIV Transcription

(2013) Malini Natarajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Histone Acetylation Switch Regulates H2A.Z Deposition by the SWR-C Remodeling Enzyme

(2013) S. Watanabe et al.   SCIENCE

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

Microprocessor, Setx, Xrn2, and Rrp6 Co-operate to Induce Premature Termination of Transcription by RNAPII

(2012) Alexandre Wagschal et al.   CELL

Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

(2012) Gaston Soria et al.   MOLECULAR CELL

New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

(2012) Karolin Luger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

(2012) Manching Ku et al.   GENOME BIOLOGY

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

The Control of HIV Transcription: Keeping RNA Polymerase II on Track

(2011) Melanie Ott et al.   Cell Host & Microbe

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency

(2011) Haleh Rafati et al.   PLOS BIOLOGY

Functional Coupling between HIV-1 Integrase and the SWI/SNF Chromatin Remodeling Complex for Efficient in vitro Integration into Stable Nucleosomes

(2011) Paul Lesbats et al.   PLoS Pathogens

Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation

(2010) Daniel A. Gilchrist et al.   CELL

HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription

(2010) Nanhai He et al.   MOLECULAR CELL

HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP

(2010) Bijan Sobhian et al.   MOLECULAR CELL

High Nucleosome Occupancy Is Encoded at Human Regulatory Sequences

(2010) Desiree Tillo et al.   PLoS One

Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex

(2010) A. Missra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention

(2010) Wade S. Blair et al.   PLoS Pathogens

The DNA-encoded nucleosome organization of a eukaryotic genome

(2008) Noam Kaplan et al.   NATURE

Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay

(2008) B. Cheng et al.   NUCLEIC ACIDS RESEARCH