Diffusion MRI reveals in vivo and non-invasively changes in astrocyte function induced by an aquaporin-4 inhibitor

Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia

(2019) Lauren M. Hablitz et al.   Science Advances

Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

(2019) Tuomas O. Lilius et al.   JOURNAL OF CONTROLLED RELEASE

Glymphatic imaging using MRI

(2019) Toshiaki Taoka et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Perivascular space fluid contributes to diffusion tensor imaging changes in white matter

(2019) Farshid Sepehrband et al.   NEUROIMAGE

Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep

(2019) Nina E. Fultz et al.   SCIENCE

The Emerging Relationship Between Interstitial Fluid–Cerebrospinal Fluid Exchange, Amyloid-β, and Sleep

(2018) Erin L. Boespflug et al.   BIOLOGICAL PSYCHIATRY

Longitudinal Study of Irradiation-Induced Brain Microstructural Alterations With S-Index, a Diffusion MRI Biomarker, and MR Spectroscopy

(2018) Elodie Anne Pérès et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Impact of the Glymphatic System on the Kinetic and Distribution of Gadodiamide in the Rat Brain

(2018) Toshiaki Taoka et al.   INVESTIGATIVE RADIOLOGY

Impact of time-of-day on diffusivity measures of brain tissue derived from diffusion tensor imaging

(2018) Cibu Thomas et al.   NEUROIMAGE

β-Amyloid accumulation in the human brain after one night of sleep deprivation

(2018) Ehsan Shokri-Kojori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

General Anesthesia Inhibits the Activity of the “Glymphatic System”

(2018) Clement Gakuba et al.   Theranostics

Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI

(2018) Ian F Harrison et al.   eLife

The Effect of Aquaporin-4 Knockout on Interstitial Fluid Flow and the Structure of the Extracellular Space in the Deep Brain

(2018) Ze Teng et al.   Aging and Disease

Apparent diffusion coefficient changes in human brain during sleep – Does it inform on the existence of a glymphatic system?

(2018) Şükrü Barış Demiral et al.   NEUROIMAGE

Cell Densities in the Mouse Brain: A Systematic Review

(2018) Daniel Keller et al.   Frontiers in Neuroanatomy

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

(2018) Humberto Mestre et al.   eLife

Non-invasive MRI of brain clearance pathways using multiple echo time arterial spin labelling: an aquaporin-4 study

(2018) Yolanda Ohene et al.   NEUROIMAGE

Aquaporin-4 Functionality and Virchow-Robin Space Water Dynamics: Physiological Model for Neurovascular Coupling and Glymphatic Flow

(2017) Tsutomu Nakada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer’s disease cases

(2017) Toshiaki Taoka et al.   JAPANESE JOURNAL OF RADIOLOGY

Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer’s disease cases

(2017) Toshiaki Taoka et al.   Japanese Journal of Radiology

Precise Cerebral Vascular Atlas in Stereotaxic Coordinates of Whole Mouse Brain

(2017) Benyi Xiong et al.   Frontiers in Neuroanatomy

Genetic compensation: A phenomenon in search of mechanisms

(2017) Mohamed A. El-Brolosy et al.   PLoS Genetics

Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease

(2016) Matthew J. Simon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

(2016) Weiguo Peng et al.   NEUROBIOLOGY OF DISEASE

Clinical Intravoxel Incoherent Motion and Diffusion MR Imaging: Past, Present, and Future

(2016) Mami Iima et al.   RADIOLOGY

Brain Drain

(2016) Maiken Nedergaard et al.   SCIENTIFIC AMERICAN

Non-invasive imaging using reporter genes altering cellular water permeability

(2016) Arnab Mukherjee et al.   Nature Communications

Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain

(2015) Jacqueline A. Hubbard et al.   ASN Neuro

Quantitative Non-Gaussian Diffusion and Intravoxel Incoherent Motion Magnetic Resonance Imaging

(2015) Mami Iima et al.   INVESTIGATIVE RADIOLOGY

Diffusion Magnetic Resonance Imaging: What Water Tells Us about Biological Tissues

(2015) Denis Le Bihan et al.   PLOS BIOLOGY

A mesoscale connectome of the mouse brain

(2014) Seung Wook Oh et al.   NATURE

Impaired Glymphatic Perfusion After Strokes Revealed by Contrast-Enhanced MRI

(2014) Thomas Gaberel et al.   STROKE

Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorder

(2013) Mark D. Shen et al.   BRAIN

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

(2013) Jeffrey J. Iliff et al.   JOURNAL OF CLINICAL INVESTIGATION

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Inhibition of aquaporin-4 significantly increases regional cerebral blood flow

(2013) Hironaka Igarashi et al.   NEUROREPORT

High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MR Images: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material

(2013) Tomonori Kanda et al.   RADIOLOGY

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Laminar-specific and developmental expression of aquaporin-4 in the mouse hippocampus

(2011) M.S. Hsu et al.   NEUROSCIENCE

N4ITK: Improved N3 Bias Correction

(2010) Nicholas J Tustison et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Brain Water Mobility Decreases after Astrocytic Aquaporin-4 Inhibition Using RNA Interference

(2010) Jérôme Badaut et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A reproducible evaluation of ANTs similarity metric performance in brain image registration

(2010) Brian B. Avants et al.   NEUROIMAGE

Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema

(2010) Hironaka Igarashi et al.   NEUROLOGICAL SCIENCES

Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema

(2010) A. S. Thrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices andin vivorevealed by two-photon microscopy

(2008) W. Christopher Risher et al.   GLIA

Visualization of Cerebrospinal Fluid Movement with Spin Labeling at MR Imaging: Preliminary Results in Normal and Pathophysiologic Conditions

(2008) Shinya Yamada et al.   RADIOLOGY