TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals

A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs

(2018) Joris Pauty et al.   EBioMedicine

Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease

(2018) Sandro Da Mesquita et al.   NATURE

Inflammaging: a new immune–metabolic viewpoint for age-related diseases

(2018) Claudio Franceschi et al.   Nature Reviews Endocrinology

Macrophage-derived foam cells impair endothelial barrier function by inducing endothelial-mesenchymal transition via CCL-4

(2017) Ying Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Organ-specific lymphatic vasculature: From development to pathophysiology

(2017) Tatiana V. Petrova et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis

(2017) Neil P. Dufton et al.   Nature Communications

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target SlugCLINICAL PERSPECTIVE

(2016) Rachel K. Hopper et al.   CIRCULATION

Fine-tuning vascular fate during endothelial-mesenchymal transition

(2016) Lin Xiao et al.   JOURNAL OF PATHOLOGY

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition

(2016) Aristidis Moustakas et al.   Journal of Clinical Medicine

Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance

(2015) Valerio Zolla et al.   AGING CELL

MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-β

(2015) Akihiro Katsura et al.   GENES TO CELLS

Lymphatic regulator PROX1 determines Schlemm’s canal integrity and identity

(2014) Dae-Young Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation-associated lymphangiogenesis: a double-edged sword?

(2014) Honsoul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma

(2014) D. R. Overby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of lymphatic regeneration and flow patterns after lymph node dissection

(2013) Katrin S. Blum et al.   BREAST CANCER RESEARCH AND TREATMENT

Smad2 Is Essential for Maintenance of the Human and Mouse Primed Pluripotent Stem Cell State

(2013) Masayo Sakaki-Yumoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF2-induced Ras–MAPK signalling maintains lymphatic endothelial cell identity by upregulating endothelial-cell-specific gene expression and suppressing TGFβ signalling through Smad2

(2013) Taeko Ichise et al.   JOURNAL OF CELL SCIENCE

Lymphatic Muscle Cells in Rat Mesenteric Lymphatic Vessels of Various Ages

(2013) Eric A. Bridenbaugh et al.   Lymphatic Research and Biology

Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression

(2013) Y. Yoshimatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory Cytokines Promote Mesenchymal Transformation in Embryonic and Adult Valve Endothelial Cells

(2012) Gretchen J. Mahler et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

(2012) Y Kanda   BONE MARROW TRANSPLANTATION

IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner

(2012) Monika Maleszewska et al.   IMMUNOBIOLOGY

Mesenteric lymph flow in adult and aged rats

(2011) Tony J. Akl et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

(2011) Hajime Mihira et al.   JOURNAL OF BIOCHEMISTRY

TGF-β-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells

(2011) Mikiko Kawata et al.   JOURNAL OF BIOCHEMISTRY

Aging-Associated Alterations in Contractility of Rat Mesenteric Lymphatic Vessels

(2011) TAKASHI NAGAI et al.   MICROCIRCULATION

Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development

(2011) I. P. Moskowitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of Transforming Growth Factor-β1 Accelerates Lymphatic Regeneration during Wound Repair

(2010) Tomer Avraham et al.   AMERICAN JOURNAL OF PATHOLOGY

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion

(2010) Y Wu et al.   BRITISH JOURNAL OF CANCER

Structural alterations of the cutaneous vasculature in aged and in photoaged human skin in vivo

(2010) Kentaro Kajiya et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

TMEPAI, a Transmembrane TGF-β-Inducible Protein, Sequesters Smad Proteins from Active Participation in TGF-β Signaling

(2010) Yukihide Watanabe et al.   MOLECULAR CELL

Inhibition of endogenous TGF-  signaling enhances lymphangiogenesis

(2008) M. Oka et al.   BLOOD

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

(2008) N. C. Johnson et al.   GENES & DEVELOPMENT

Snail is required for TGF -induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells

(2008) T. Kokudo et al.   JOURNAL OF CELL SCIENCE

Lymphatic drainage function and its immunological implications: From dendritic cell homing to vaccine design

(2008) Melody A. Swartz et al.   SEMINARS IN IMMUNOLOGY