Adenosine leakage from perforin-burst extracellular vesicles inhibits perforin secretion by cytotoxic T-lymphocytes

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

(2018) Franz L. Ricklefs et al.   Science Advances

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Methodical Challenges and a Possible Resolution in the Assessment of Receptor Reserve for Adenosine, an Agonist with Short Half-Life

(2017) Judit Zsuga et al.   MOLECULES

Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes

(2017) Maija Puhka et al.   Theranostics

Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism

(2017) James R. Krycer et al.   Cell Reports

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

(2017) Angel Garcia-Diaz et al.   Cell Reports

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

(2016) Jianjun Gao et al.   CELL

Immunomodulatory role of microRNAs transferred by extracellular vesicles

(2015) Lola Fernández-Messina et al.   BIOLOGY OF THE CELL

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p

(2015) Guoping Ding et al.   Oncotarget

Adenosine Receptor 2A Blockade Increases the Efficacy of Anti–PD-1 through Enhanced Antitumor T-cell Responses

(2015) Paul A. Beavis et al.   Cancer Immunology Research

Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors

(2015) Michael Platten et al.   Frontiers in Immunology

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

(2014) T. Umezu et al.   BLOOD

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes

(2014) S S Metkar et al.   CELL DEATH AND DIFFERENTIATION

Perforin: an important player in immune response

(2014) Iwona Osińska et al.   Central European Journal of Immunology

IFN-γ regulates survival and function of tumor-induced CD11b+Gr-1highmyeloid derived suppressor cells by modulating the anti-apoptotic molecule Bcl2a1

(2014) José Medina-Echeverz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

(2013) J. A. Lopez et al.   BLOOD

CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function

(2013) Lesley Ann Smyth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

(2013) Hiroko Tadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The adenosinergic system in cancer

(2013) Rosalinda Sorrentino et al.   OncoImmunology

Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production

(2011) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

IDO: more than an enzyme

(2011) WanJun Chen   NATURE IMMUNOLOGY

Metabolomic Profiling of Anionic Metabolites by Capillary Electrophoresis Mass Spectrometry

(2009) Tomoyoshi Soga et al.   ANALYTICAL CHEMISTRY

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

(2009) Masahiro Sugimoto et al.   Metabolomics