Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations

A lipolysis-permeation setup for simultaneous study of digestion and absorption in vitro

(2019) Janneke Keemink et al.   MOLECULAR PHARMACEUTICS

Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire® 44/14

(2019) Dong Shin et al.   Pharmaceutics

Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment

(2019) Mohsin Kazi et al.   Frontiers in Pharmacology

Interplay of Supersaturation and Solubilization: Lack of Correlation between Concentration-Based Supersaturation Measurements and Membrane Transport Rates in Simulated and Aspirated Human Fluids

(2019) Ahmed Elkhabaz et al.   MOLECULAR PHARMACEUTICS

Lipid based delivery of Efavirenz: An answer to its erratic absorption and food effect

(2018) Sunil Kamboj et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Assessment of Passive Intestinal Permeability Using an Artificial Membrane Insert System

(2018) Philippe Berben et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations

(2018) Janneke Keemink et al.   PHARMACEUTICAL RESEARCH

Exploring the utility of the Chasing Principle: Influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

(2018) Scheyla Siqueira Jørgensen et al.   Acta Pharmaceutica Sinica B

Using pH Gradient Dissolution with In-Situ Flux Measurement to Evaluate Bioavailability and DDI for Formulated Poorly Soluble Drug Products

(2018) Jane Li et al.   AAPS PHARMSCITECH

Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

(2018) Linda C. Alskär et al.   MOLECULAR PHARMACEUTICS

Assessment of cell viability and permeation enhancement in presence of lipid-based self-emulsifying drug delivery systems using Caco-2 cell model: Polysorbate 80 as the surfactant

(2017) Pengli Bu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Simultaneous lipolysis/permeation in vitro model, for the estimation of bioavailability of lipid based drug delivery systems

(2017) Hanady Ajine Bibi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Piperine-pro-nanolipospheres as a novel oral delivery system of cannabinoids: Pharmacokinetic evaluation in healthy volunteers in comparison to buccal spray administration

(2017) Irina Cherniakov et al.   JOURNAL OF CONTROLLED RELEASE

50 years of oral lipid-based formulations: Provenance, progress and future perspectives

(2016) Orlagh M. Feeney et al.   ADVANCED DRUG DELIVERY REVIEWS

Development of a μDissolution-Permeation model with in situ drug concentration monitoring

(2016) Ragna Berthelsen et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

31P and 1H NMR Studies of the Molecular Organization of Lipids in the Parallel Artificial Membrane Permeability Assay

(2016) Frauke Assmus et al.   MOLECULAR PHARMACEUTICS

In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

(2014) Nicky Thomas et al.   AAPS Journal

Biopharmaceutical Modeling of Drug Supersaturation During Lipid-Based Formulation Digestion Considering an Absorption Sink

(2014) Cordula Stillhart et al.   PHARMACEUTICAL RESEARCH

Analysis of the enhanced oral bioavailability of fenofibrate lipid formulations in fasted humans using an in vitro–in silico–in vivo approach

(2013) Yang Fei et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: Case studies with fenofibrate

(2013) Brendan T. Griffin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Insights into Drug Precipitation Kinetics during In Vitro Digestion of a Lipid-Based Drug Delivery System Using In-Line Raman Spectroscopy and Mathematical Modeling

(2013) Cordula Stillhart et al.   PHARMACEUTICAL RESEARCH

Bioavailability of Cinnarizine in Dogs: Effect of SNEDDS Loading Level and Correlation with Cinnarizine Solubilization During In Vitro Lipolysis

(2013) Anne T. Larsen et al.   PHARMACEUTICAL RESEARCH

Properties and biotechnological applications of porcine pancreatic lipase

(2012) Adriano A. Mendes et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

(2012) Hywel D. Williams et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Biorelevant in vitro dissolution testing of products containing micronized or nanosized fenofibrate with a view to predicting plasma profiles

(2010) Daniel Juenemann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

(2010) Anette Müllertz et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Culture conditions and treatments affect Caco-2 characteristics and particle uptake

(2009) S.M. Moyes et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS