Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Morotti, Giorgio Busto, Gregoire Boulouis, Elisa Scola, Alessandro Padovani, Ilaria Casetta, Enrico Fainardi
Summary: The combined analysis of non-contrast CT and CT perfusion markers improves the prediction of hematoma expansion and outcome in intracerebral hemorrhage.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Nefeli Valyraki, Adrien Goujon, Marjorie Mateos, Adrien Lecoeuvre, Augustin Lecler, Igor Raynouard, Candice Sabben, Michael Obadia, Julien Savatovsky, Pierre Seners
Summary: The presence of MRI spot sign in patients with acute intracerebral hemorrhage is independently associated with hematoma expansion and poor functional outcome. The number of spot signs shows a dose-dependent effect on hematoma expansion and poor functional outcome.
JOURNAL OF NEUROLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jawed Nawabi, Frieder Schlunk, Andrea Dell Orco, Sarah Elsayed, Federico Mazzacane, Dmitriy Desser, Ly Vu, Estelle Vogt, Haoyin Cao, Maik F. H. Boehmer, Burak Han Akkurt, Peter B. Sporns, Marco Pasi, Ulf Jensen-Kondering, Gabriel Broocks, Tobias Penzkofer, Jens Fiehler, Alessandro Padovani, Uta Hanning, Andrea Morotti
Summary: Non-contrast computed tomography (NCCT) markers are reliable predictors for predicting parenchymal hematoma expansion in intracerebral hemorrhage (ICH). This study investigates whether NCCT features can also identify patients at risk of intraventricular hemorrhage (IVH) growth.
EUROPEAN RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Robert Raschke, Pooja Rangan, Sumit C. Agarwal, Suresh Uppalapu, Nehan Sher, Steven Curry, C. William Heise
Summary: This study developed a mortality prediction system called C-TIME specifically for COVID-19 patients requiring intubation. It demonstrated acceptable discrimination accuracy and can assist in decision-making prior to intubation.
Article
Cardiac & Cardiovascular Systems
Jessica Magid-Bernstein, Romuald Girard, Sean Polster, Abhinav Srinath, Sharbel Romanos, Issam A. Awad, Lauren H. Sansing
Summary: This review article provides an overview of the epidemiology, cause, mechanisms of injury, current treatment strategies, and future research directions of intracerebral hemorrhage (ICH). The incidence of hemorrhagic stroke has increased globally in the past 40 years, with changes in the cause over time due to improved hypertension management and increased use of anticoagulants. Preclinical and clinical trials have shed light on the underlying cause and mechanisms of injury from ICH, including the complex interaction between edema, inflammation, iron-induced injury, and oxidative stress. Although several trials have investigated the optimal medical and surgical management of ICH, there has been no clear improvement in survival and functional outcomes. Ongoing research into novel approaches for ICH management offers hope for reducing the devastating impact of this disease in the future.
CIRCULATION RESEARCH
(2022)
Article
Neurosciences
Shijian Chen, Jian Zhang, Xianfu Lu, Gengyu Cen, Yiting Song, Xuhui Deng, Yiju Xie, Liuyu Liu, Qianqian Liu, Junling Huang, Jing Li, Hong Yang, Shengliang Shi, Liya Pan, Zhijian Liang
Summary: This study investigated the clinical features, risk factors, and underlying pathogenesis of cancer related SAH. The results showed that patients with cancer related SAH had poor outcomes, and a decrease in platelet and prolonged prothrombin time were identified as independent risk factors. The joint predictive factor with a cutoff value of 11.719 could serve as a novel biomarker for cancer related SAH.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Clinical Neurology
Trine Apostolaki-Hansson, Teresa Ullberg, Mats Pihlsgard, Bo Norrving, Jesper Petersson
Summary: This study found that both OAC-related ICH and antiplatelet-related ICH had worse 90-day mortality outcomes compared to nonantithrombotic ICH. Antiplatelet-related ICH is common and associated with poor clinical outcomes, warranting further research to determine appropriate clinical management.
Article
Medicine, General & Internal
Feng Wei, Yan Cui, Xiuhua Guo, Guoping Dong, Xiulong LI
Summary: This study explored the correlations between inflammatory factors, CCCK-18, MMP-9, DD and the APACHE II Score and prognosis of patients with ACH. The results showed that the APACHE II Score was positively associated with the levels of inflammatory factors, CCCK-18, MMP-9, and DD. Increased levels of hs-CRP, CCCK-18, MMP-9, and DD were identified as independent risk factors for poor neurologic outcomes in ACH patients.
Article
Clinical Neurology
Apostolos Safouris, Lina Palaiodimou, Sandor Nardai, Odysseas Kargiotis, George Magoufis, Klearchos Psychogios, Marius Matusevicius, Katharina Feil, Niaz Ahmed, Lars Kellert, Stavros Spiliopoulos, Elias Brountzos, Istvan Szikora, Amrou Sarraj, Nitin Goyal, Diana Aguiar de Sousa, Daniel Strbian, Valeria Caso, Andrei V. Alexandrov, Georgios Tsivgoulis
Summary: For anterior circulation large-vessel occlusion ischemic stroke patients with low baseline National Institutes of Health Stroke Scale score, EVT appears to be equivalent to BMT in terms of excellent functional outcome, but it carries an increased risk of symptomatic intracranial hemorrhage.
Article
Neurosciences
Jiawen Li, Dong Luo, Feifei Peng, Qi Kong, Huawei Liu, Meiyuan Chen, Lusha Tong, Feng Gao
Summary: The novel ANAID-ICH nomogram, incorporating age, NIHSS score, anemia, infratentorial location, presence of DWILs, and prior ICH, may facilitate the identification of patients at higher risk for an unfavorable outcome.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zuhua Song, Zhuoyue Tang, Huan Liu, Dajing Guo, Jinhua Cai, Zhiming Zhou
Summary: This study developed and validated a clinical-radiomics nomogram based on NCCT to identify sICH patients with poor 90-day prognosis. The nomogram, consisting of six independent predictors, showed good predictive performance in different cohorts, providing accurate risk assessment for sICH patients.
EUROPEAN RADIOLOGY
(2021)
Article
Critical Care Medicine
Kun He Lee, Vasileios-Arsenios Lioutas, Sarah Marchina, Magdy Selim
Summary: This study found that an early increase in ventricular size is independently associated with lower odds of good clinical outcome in the context of intracerebral hemorrhage, while measures of perihematomal edema (PHE) were not significantly associated with outcome.
NEUROCRITICAL CARE
(2022)
Article
Clinical Neurology
Erik Lindgren, Katarzyna Krzywicka, Maria A. de Winter, Mayte Sanchez Van Kammen, Mirjam R. Heldner, Sini Hiltunen, Diana Aguiar de Sousa, Maryam Mansour, Patricia Canhao, Esme Ekizoglu, Miguel Rodrigues, Elisa Martins Silva, Carlos Garcia-Esperon, Valentina Arnao, Paolo Aridon, Naaem Moin Simaan, Suzanne M. Silvis, Susanna M. Zuurbier, Adrian Scutelnic, Mine Sezgin, Andrey Marisovich Alasheev, Andrey Smolkin, Daniel Guisado-Alonso, Nilufer Yesilot, Miguel Barboza, Masoud Ghiasian, Ronen R. Leker, Antonio Arauz, Marcel Arnold, Jukka Putaala, Turgut Tatlisumak, Jonathan M. Coutinho, Katarina Jood
Summary: A prognostic score was developed to predict dependency and death after cerebral venous thrombosis (CVT). The SI(2)NCAL(2)C score showed adequate performance in estimating individual risk of mortality and dependency after CVT.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Critical Care Medicine
Spyridon Fortis, Amy M. J. O'Shea, Brice F. Beck, Rajeshwari Nair, Michihiko Goto, Gregory A. Schmidt, Peter J. Kaboli, Eli N. Perencevich, Heather Schacht Reisinger, Mary Vaughan Sarrazin
Summary: The study aimed to develop a simplified critical illness severity scoring system with high prediction accuracy for 30-day mortality using commonly available variables. The newly created system showed excellent performance in predicting 30-day mortality internally and required easily extracted commonly used variables from electronic health records.
JOURNAL OF CRITICAL CARE
(2021)
Article
Clinical Neurology
Martina B. Goeldlin, Achim Mueller, Bernhard M. Siepen, Madlaine Mueller, Davide Strambo, Patrik Michel, Michael Schaerer, Carlo W. Cereda, Giovanni Bianco, Florian Lindheimer, Christian Berger, Friedrich Medlin, Roland Backhaus, Nils Peters, Susanne Renaud, Loraine Fisch, Julien Niederhaeuser, Emmanuel Carrera, Elisabeth Dirren, Christophe Bonvin, Rolf Sturzenegger, Timo Kahles, Krassen Nedeltchev, Georg Kaegi, Jochen Vehoff, Biljana Rodic, Manuel Bolognese, Ludwig Schelosky, Stephan Salmen, Marie-Luise Mono, Alexandros A. Polymeris, Stefan T. Engelter, Philippe Lyrer, Susanne Wegener, Andreas R. Luft, Werner Z'Graggen, David Bervini, Bastian Volbers, Tomas Dobrocky, Johannes Kaesmacher, Pasquale Mordasini, Thomas R. Meinel, Marcel Arnold, Javier Fandino, Leo H. Bonati, Urs Fischer, David J. Seiffge
Summary: Knowledge about different etiologies of non-traumatic intracerebral hemorrhage (ICH) and their outcomes is scarce. Hypertension is the leading etiology of ICH, but other etiologies are also common. Around one-third of patients achieve functional independence at 3 months, but the mortality rate is high. The risk of ischemic stroke within 3 months of ICH is higher than the risk of recurrent hemorrhage, except for patients with cerebral amyloid angiopathy (CAA).
Article
Medicine, General & Internal
S. Guney Pinar, M. Pekdemir, I. U. Ozturan, N. O. Dogan, E. Yaka, S. Yilmaz, A. Karadas, D. Ferek Emir
Summary: This study investigates the accuracy of variations in end-tidal carbon dioxide (ETCO2) and inferior vena cava collapsibility index (IVCCI) gradient in predicting volume responsiveness in spontaneously breathing patients with hypovolemia. The results suggest that ETCO2 difference can be an alternative method in predicting volume responsiveness in this patient population.
MEDIZINISCHE KLINIK-INTENSIVMEDIZIN UND NOTFALLMEDIZIN
(2022)
Article
Medicine, General & Internal
Nermin Kilicarslan, Hande Gurbuz, Sermin Eminoglu, Sedef Elmas Arslan, Derya Karasu, Buket Ozyaprak, Mehmet Gamli
Summary: After the COVID-19 pandemic, there have been changes in code blue practices. This study compared the code blue practices between the first year of COVID-19 and the previous year. The results showed an increase in the incidence of code blue in the COVID-19 period, and there were significant differences in arrival time, return of spontaneous circulation (ROSC), and survival rates. Faulty code blue calls may predict poor prognosis, highlighting the need for early warning systems for patients in critical condition.
HASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKI
(2022)
Article
Clinical Neurology
Hande Gurbuz, Mehmet Secer, Aykut Gokbel
Summary: This study aimed to observe the long-term effect of epidural steroid injections (ESI) and describe surgical outcomes in patients with far-lateral lumbar disc herniations. The medical records of 30 patients who underwent surgery for far-lateral lumbar disc herniations were reviewed. The results showed that ESI can provide significant pain relief and delay the need for surgery, but persistent back pain and sensory abnormalities may still exist.
Article
Medicine, General & Internal
Nermin Kilicarslan, Hande Gurbuz, Fatma Nurgul Tasgoz, Umran Karaca, Derya Karasu, Mehmet Gamli
Summary: This study aimed to evaluate maternal and fetal characteristics and factors affecting fetal outcomes in twin pregnancies delivered by cesarean section. The results showed that early gestational weeks and birth weight <3rd weight percentile were the most significant predictors of poor neonatal outcomes in at least one of the twins. General anesthesia and emergency surgery were also associated with poor outcomes in at least one of the twins. Therefore, interventions should aim to optimize these factors to improve neonatal outcomes in twin pregnancies delivered by cesarean section.
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
(2023)
Article
Medicine, General & Internal
Mehmet Secer, Hande Gurbuz, Anil Gulcu
Summary: This observational study aimed to investigate the effect of combining ligamentotaxis with a posterior surgical approach in thoracic and lumbar burst fractures with high McCormack scores. The study evaluated medical records of 16 patients from January 2015 to December 2020. Postoperative measurements showed significant changes in vertebral height, kyphosis angle, and spinal canal diameter. However, no significant neurological improvement was observed in cases with neurological deficits.
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
(2023)
Article
Anesthesiology
Dilek Guven Taymez, Ozge Telci Caklili, Hande Gurbuz
Summary: This report describes a case of acute renal failure and delayed paralysis caused by the ingestion of a large dose of Maneb for a suicide attempt. The patient was admitted to the emergency room after consuming almost a whole bottle of Maneb. Despite treatment, the patient experienced muscle weakness and dyspnea, requiring intubation. After several weeks of intensive care and nephrology treatment, the patient was discharged with persistent bilateral drop foot.
TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sevtap Dogan, Gozde Selvi Guldiken, Burcu Alpaslan, Serap Argun Baris, Nurettin Ozgur Dogan
Summary: This study evaluated the CT scores and fibrotic pattern changes in interstitial lung disease (ILD) patients, with and without previous COVID-19 pneumonia. The results showed that in patients with COVID-19 pneumonia, there was a significant increase in CT scores and worsening of the fibrotic pattern.
EUROPEAN RADIOLOGY
(2023)
Article
Respiratory System
Sevtap Dogan, Onural Ozturk, Sevil Aydoan Dis, Serap Argun Baris, Nurettin Ozgur Dogan
Summary: The presentation of elderly-onset sarcoidosis appears to differ from young-onset sarcoidosis. Elderly patients more frequently demonstrated comorbidities such as arthralgia and coronary artery disease, and had a lower proportion of clinical remission. Additionally, radiologically, lymph node enlargement and a distinctive pattern of fibrosis were more common in elderly patients.
SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES
(2023)
Article
Anesthesiology
Hande Gurbuz, Hulya Topcu
Summary: This study aimed to evaluate Acute Physiology and Chronic Health Evaluation-II and Intracerebral Haemorrhage scores in spontaneous intracerebral haemorrhage patients treated in intensive care units. The results showed that the Acute Physiology and Chronic Health Evaluation-II score is a better predictor than the Intracerebral Haemorrhage score for in-hospital mortality and functional outcomes. However, the Intracerebral Haemorrhage score can still be used as an indicator of neurological status.
TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
(2022)
Article
Computer Science, Theory & Methods
Selcuk Ogutcu, Melih Inal, Cantekin Celikhasi, Ugur Yildiz, Nurettin Ozgur Dogan, Murat Pekdemir
Summary: This paper examines the biochemical findings of patients with suspicion of COVID-19 who sought treatment at the Kocaeli University Faculty of Medicine Emergency Service. It proposes a method that utilizes factor analysis and an artificial neural network to detect severe cases early and determine vaccination priority for non-risk groups.
ROMANIAN JOURNAL OF INFORMATION SCIENCE AND TECHNOLOGY
(2022)
Article
Medicine, General & Internal
Hande Gurbuz, Nalan Demir
Summary: High-energy chest wall traumas often result in multiple rib fractures, leading to high morbidity and mortality. Pulmonary morbidity in patients with multiple rib fractures is caused by impaired gas exchange in the damaged lung areas and compromised breathing mechanics due to severe pain. Therefore, adequate pain management is crucial in the management of rib fractures. Erector spinae plane (ESP) block is a newly developed technique that has been used in emergency departments for posterior rib fractures. This report presents anecdotal evidence of three patients with multiple rib fractures who benefited from ESP blocks.
AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY
(2022)
Article
Obstetrics & Gynecology
Gulfem Basol, Ahmet Kale, Hande Gurbuz, Elif Cansu Gundogdu, Kursad Nuri Baydilli, Taner Usta
Summary: This study evaluated the 2-year outcomes of repetitive transvaginal pudendal nerve injections (PNI) and compared the success of PNI at different anatomical levels. The efficacy of PNI decreased over time and was more effective for pudendal nerve entrapment between ligaments compared to the endopelvic part. However, therapeutic nerve blocks are still recommended for suspected endopelvic pudendal nerve pathology before surgery referral.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Emergency Medicine
Sevinc Tas Caylak, Elif Yaka, Serkan Yilmaz, Nurettin Ozgur Dogan, Ibrahim Ulas Ozturan, Murat Pekdemir
Summary: This study compared the performance of the PECARN decision rule and clinician suspicion in identifying low-risk children for intra-abdominal injuries. The results showed that both methods had similar sensitivity in detecting intra-abdominal injuries in children with blunt torso trauma. However, the study supports the use of the PECARN abdominal rule in addition to clinical judgment to reduce unnecessary abdominal CT use in pediatric patients.
ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
(2022)
Article
Anesthesiology
Korgun Okmen, Hande Gurbuz, Hakan Ozkan
Summary: This study found that unilateral rhomboid intercostal and subserratus plane (RISS) block can effectively reduce the amount of analgesic consumption and decrease postoperative pain after laparoscopic cholecystectomy. This method can be used as part of multimodal analgesia.
KOREAN JOURNAL OF ANESTHESIOLOGY
(2022)