Transition-Metal-Catalyzed Asymmetric Hydrogenation and Transfer Hydrogenation: Sustainable Chemistry to Access Bioactive Molecules

Recent Developments in Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones and Imines through Dynamic Kinetic Resolution

(2016) Phannarath Phansavath et al.   SYNTHESIS-STUTTGART

Iron-, Cobalt-, and Nickel-Catalyzed Asymmetric Transfer Hydrogenation and Asymmetric Hydrogenation of Ketones

(2015) Yan-Yun Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis, characterization and use of a new tethered Rh(III) complex in asymmetric transfer hydrogenation of ketones

(2015) Pierre-Georges Echeverria et al.   CATALYSIS COMMUNICATIONS

The Golden Age of Transfer Hydrogenation

(2015) Dong Wang et al.   CHEMICAL REVIEWS

Efficient Synthesis of Differentiatedsyn-1,2-Diol Derivatives by Asymmetric Transfer Hydrogenation-Dynamic Kinetic Resolution of α-Alkoxy-Substituted β-Ketoesters

(2015) Laure Monnereau et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Efficient Stereoselective Total Synthesis of All Stereoisomers of the Antibiotic Thiamphenicol through Ruthenium-Catalyzed Asymmetric Reduction by Dynamic Kinetic Resolution

(2015) Marc Perez et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of 1-Aryl-Substituted Tetrahydroisoquinolines Through Ru-Catalyzed Asymmetric Transfer Hydrogenation

(2015) Marc Perez et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficiency of Industrially Relevant Atropisomeric Diphosphines in Copper-Catalyzed 1,4-Asymmetric Conjugate Addition of Dialkylzincs to Cyclic or Acyclic Enones or Dienones

(2015) Christophe Crévisy et al.   SYNTHESIS-STUTTGART

Catalytic asymmetric transfer hydrogenation of ketones: recent advances

(2015) Francisco Foubelo et al.   TETRAHEDRON-ASYMMETRY

Asymmetric transfer hydrogenation of α-amino β-keto ester hydrochlorides through dynamic kinetic resolution

(2015) Pierre-Georges Echeverria et al.   RSC Advances

Hydrogen: a good partner for rhodium-catalyzed hydrosilylation

(2014) Cédric Balan et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Advances in Catalyst Systems for the Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones

(2014) Bogdan Štefane et al.   CATALYSIS REVIEWS-SCIENCE AND ENGINEERING

Expanding the Chemical Diversity in Artificial Imine Reductases Based on the Biotin-Streptavidin Technology

(2014) Tommaso Quinto et al.   ChemCatChem

Diastereo- and Enantioselectiveanti-Selective Hydrogenation of α-Amino-β-keto Ester Hydrochlorides and Related Compounds Using Transition-Metal-Chiral-Bisphosphine Catalysts

(2014) Yasumasa Hamada   CHEMICAL RECORD

Electron-Deficient Diphosphines: The Impact of DIFLUORPHOS in Asymmetric Catalysis

(2014) Jean-Pierre Genet et al.   CHEMICAL REVIEWS

Ruthenium-Catalyzed Tandem-Isomerization/Asymmetric Transfer Hydrogenation of Allylic Alcohols

(2014) Tove Slagbrand et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Ruthenium(II)/Xyl-SunPhos/Daipen-Catalyzed Hydrogenation of γ-Ketoamides

(2014) Mengmeng Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthetic Strategy toward the C44–C65 Fragment of Mirabalin

(2014) Pierre-Georges Echeverria et al.   ORGANIC LETTERS

An Improved and Efficient Process for the Preparation of Tofacitinib Citrate

(2014) Yogesh S. Patil et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Short and Straightforward Enantioselective Synthesis of Both Enantiomers of Mequitazine through Iridium-Catalyzed Asymmetric Hydrogenation of a Nonfunctionalized Cyclic Enamine

(2014) Philippe Maillos et al.   SYNLETT

Iridium–SYNPHOS-Catalyzed Hydrogenation through Dynamic Kinetic Resolution of α-Amino β-Keto Ester Hydrochlorides

(2014) Phannarath Phansavath et al.   SYNLETT

Recent Advances in the Development of Chiral Metal Catalysts for the Asymmetric Hydrogenation of Ketones

(2014) Jian-Hua Xie et al.   SYNTHESIS-STUTTGART

Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation of 1-Aryl-Substituted Dihydroisoquinolines: Access to Valuable Chiral 1-Aryl-Tetrahydroisoquinoline Scaffolds

(2013) Zi Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric transfer hydrogenation of 1-phenyl dihydroisoquinolines using Ru(II) diamine catalysts

(2013) Jan Přech et al.   CATALYSIS COMMUNICATIONS

Enantioselective Synthesis of Alcohols and Amines by Iridium-Catalyzed Hydrogenation, Transfer Hydrogenation, and Related Processes

(2013) Agnieszka Bartoszewicz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Quantum Chemical Calculations with the Inclusion of Nonspecific and Specific Solvation: Asymmetric Transfer Hydrogenation with Bifunctional Ruthenium Catalysts

(2013) Pavel A. Dub et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic kinetic resolution of β′-keto-β-amino esters using Ru–DTBM–Sunphos catalyzed asymmetric hydrogenation

(2013) Xiaoming Li et al.   TETRAHEDRON

Palladium-Catalyzed Efficient Enantioselective Synthesis of Chiral Allenes: Steric and Electronic Effects of Ligands

(2013) Zi Wu et al.   ACS Catalysis

Aromatic Interactions as Control Elements in Stereoselective Organic Reactions

(2012) Elizabeth H. Krenske et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ru-catalyzed highly chemo- and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters under neutral conditions

(2012) Xin Ma et al.   CHEMICAL COMMUNICATIONS

Asymmetric homogeneous hydrogenations at scale

(2012) David J. Ager et al.   CHEMICAL SOCIETY REVIEWS

Homogeneous palladium-catalyzed asymmetric hydrogenation

(2012) Qing-An Chen et al.   CHEMICAL SOCIETY REVIEWS

Access to Optically Active 3-Aminopiperidines by Ring Expansion of Prolinols: Thermodynamic versus Kinetic Control

(2012) Anne Cochi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

General Asymmetric Hydrogenation of 2-Alkyl- and 2-Aryl-Substituted Quinoxaline Derivatives Catalyzed by Iridium-Difluorphos: Unusual Halide Effect and Synthetic Application

(2012) Damien Cartigny et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Rhodium-Catalyzed Synthesis of α-Chloromethylene-γ-Butyrolactams from N-Allylic Alkynamides

(2012) Olivier Jackowski et al.   ORGANIC LETTERS

Enantioselective Synthesis of 1-Aryl-tetrahydroisoquinolines through Iridium Catalyzed Asymmetric Hydrogenation

(2012) Farouk Berhal et al.   ORGANIC LETTERS

The Development of an Asymmetric Hydrogenation Process for the Preparation of Solifenacin

(2012) Miloš Ružič et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Transfer Hydrogenation of Acetophenone N-Benzylimine Using [RuIICl((S,S)-TsDPEN)(η6-p-cymene)]: A DFT Study

(2012) Petr Šot et al.   ORGANOMETALLICS

Total Synthesis of Symbioramide: a Flexible Approach for the Efficient Preparation of Structural Isomers

(2011) Sébastien Prévost et al.   ADVANCED SYNTHESIS & CATALYSIS

A Highly Efficient and Enantioselective Access to Tetrahydroisoquinoline Alkaloids: Asymmetric Hydrogenation with an Iridium Catalyst

(2011) Mingxin Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Use of Nonfunctionalized Enamides and Enecarbamates in Asymmetric Synthesis

(2011) Kovuru Gopalaiah et al.   CHEMICAL REVIEWS

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

Rh-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Ketones with DIFLUORPHOS and SYNPHOS Analogues

(2011) Farouk Berhal et al.   JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Enantioselective Hydrogenation of Aryl-Pyridyl Ketones

(2011) Xiaoming Tao et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic anti-Selective Asymmetric Hydrogenation of .ALPHA.-Amino-.BETA.-Keto Esters through Dynamic Kinetic Resolution

(2011) Yasumasa Hamada et al.   JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN

The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines

(2011) Rina Soni et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Efficient Enantioselective Synthesis of 3-Aminochroman Derivatives Through Ruthenium-Synphos Catalyzed Asymmetric Hydrogenation

(2011) Zi Wu et al.   ORGANIC LETTERS

(R)-3,5-diCF3-SYNPHOS and (R)-p-CF3-SYNPHOS, Electron-Poor Diphosphines for Efficient Room Temperature Rh-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids

(2011) Farouk Berhal et al.   ORGANIC LETTERS

Asymmetric Transfer Hydrogenation of Imines and Ketones Using Chiral RuIICl(η6-p-cymene)[(S,S)-N-TsDPEN] as a Catalyst: A Computational Study

(2011) Jiří Václavík et al.   ORGANOMETALLICS

Recent developments in dynamic kinetic resolution

(2011) Hélène Pellissier   TETRAHEDRON

Iridium-Difluorphos-Catalyzed Asymmetric Hydrogenation of 2-Alkyl- and 2-Aryl-Substituted Quinoxalines: A General and Efficient Route into Tetrahydroquinoxalines

(2010) Damien Cartigny et al.   ADVANCED SYNTHESIS & CATALYSIS

Chemistry ofConcertoMolecular Catalysis Based on the Metal/NH Bifunctionality

(2010) Takao Ikariya   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

(2010) Jian-Hua Xie et al.   CHEMICAL REVIEWS

Diastereo- and Enantioselective Hydrogenation of α-Amino-β-Keto Ester Hydrochlorides Catalyzed by an Iridium Complex with MeO-BIPHEP and NaBArF: Catalytic Cycle and Five-Membered Chelation Mechanism of Asymmetric Hydrogenation

(2010) Tsukuru Maeda et al.   CHEMISTRY-A EUROPEAN JOURNAL

Privileged scaffolds for library design and drug discovery

(2010) Matthew E Welsch et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Highly Diastereo- and Enantioselective Synthesis of Monodifferentiatedsyn-1,2-Diol Derivatives through Asymmetric Transfer Hydrogenation via Dynamic Kinetic Resolution

(2010) Damien Cartigny et al.   ORGANIC LETTERS

Enantioselective Synthesis ofanti-β-Hydroxy-α-amido Esters via Transfer Hydrogenation

(2010) Brinton Seashore-Ludlow et al.   ORGANIC LETTERS

Asymmetric hydrogenation of trisubstituted N-acetyl enamides derived from 2-tetralones using ruthenium-SYNPHOS catalysts: a practical synthetic approach to the preparation of β3-adrenergic agonist SR58611A

(2010) Cyrielle Pautigny et al.   TETRAHEDRON-ASYMMETRY

Dynamic kinetic resolution of α-chloro β-keto esters and phosphonates: hemisynthesis of Taxotere® through Ru-DIFLUORPHOS asymmetric hydrogenation

(2010) Sébastien Prévost et al.   TETRAHEDRON-ASYMMETRY

Expedient Synthesis of Mequitazine an Antihistaminic Drug by Palladium Catalyzed Allylic Alkylation of Sodium Phenothiazinate

(2009) Vanessa Gonnot et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

A Highly Enantioselective Access to Tetrahydroisoquinoline and β-Carboline Alkaloids with Simple Noyori-Type Catalysts in Aqueous Media

(2009) Laurent Evanno et al.   CHEMISTRY-A EUROPEAN JOURNAL

Unprecedented Halide Dependence on Catalytic Asymmetric Hydrogenation of 2-Aryl- and 2-Alkyl-Substituted Quinolinium Salts by Using Ir Complexes with Difluorphos and Halide Ligands

(2009) Hiroshi Tadaoka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mirabalin, an Antitumor Macrolide Lactam from the Marine SpongeSiliquariaspongia mirabilis

(2009) Alberto Plaza et al.   JOURNAL OF NATURAL PRODUCTS

Sulfonamido−Phosphoramidite Ligands in Cooperative Dinuclear Hydrogenation Catalysis

(2009) Frederic W. Patureau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Total Synthesis and Stereochemical Revision of Gymnangiamide

(2009) Hitoshi Tone et al.   ORGANIC LETTERS

Ru(II) Complexes of N-Alkylated TsDPEN Ligands in Asymmetric Transfer Hydrogenation of Ketones and Imines

(2009) José E. D. Martins et al.   ORGANIC LETTERS

Broader, Greener, and More Efficient: Recent Advances in Asymmetric Transfer Hydrogenation

(2008) Chao Wang et al.   Chemistry-An Asian Journal

Discovery of a Novel Series of Benzoic Acid Derivatives as Potent and Selective Human β3Adrenergic Receptor Agonists with Good Oral Bioavailability. 3. Phenylethanolaminotetraline (PEAT) Skeleton Containing Biphenyl or Biphenyl Ether Moiety

(2008) Masashi Imanishi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mirabilin, an Antitumor Macrolide Lactam from the Marine SpongeSiliquariaspongia mirabilis†

(2008) Alberto Plaza et al.   JOURNAL OF NATURAL PRODUCTS

Ruthenium-SYNPHOS-Catalyzed Asymmetric Hydrogenations: an Entry to Highly Stereoselective Synthesis of the C15−C30 Subunit of Dolabelide A

(2008) Christophe Roche et al.   ORGANIC LETTERS

Ruthenium-catalyzed asymmetric hydrogenation of N-(3,4-dihydro-2-naphthalenyl)-acetamide

(2007) Xavier Sala et al.   CATALYSIS COMMUNICATIONS

Recent developments in dynamic kinetic resolution

(2007) Hélène Pellissier   TETRAHEDRON