Harnessing cell-free DNA: plasma circulating tumour DNA for liquid biopsy in genitourinary cancers
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Title
Harnessing cell-free DNA: plasma circulating tumour DNA for liquid biopsy in genitourinary cancers
Authors
Keywords
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Journal
Nature Reviews Urology
Volume 17, Issue 5, Pages 271-291
Publisher
Springer Science and Business Media LLC
Online
2020-03-18
DOI
10.1038/s41585-020-0297-9
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Note: Only part of the references are listed.- Circulating Tumor DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer
- (2019) Gillian Vandekerkhove et al. EUROPEAN UROLOGY
- Tumor mutational burden (TMB) standardization initiatives: Recommendations for consistent TMB assessment in clinical samples to guide immunotherapy treatment decisions
- (2019) Albrecht Stenzinger et al. GENES CHROMOSOMES & CANCER
- Assessment of Blood Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Patients With Non–Small Cell Lung Cancer With Use of a Next-Generation Sequencing Cancer Gene Panel
- (2019) Zhijie Wang et al. JAMA Oncology
- Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
- (2019) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
- (2019) Brian I. Rini et al. NEW ENGLAND JOURNAL OF MEDICINE
- Understanding, justifying, and optimizing radiation exposure for CT imaging in nephrourology
- (2019) Andrea Ferrero et al. Nature Reviews Urology
- High dose testosterone in men with metastatic castrate-resistant prostate cancer (mCRPC) and homologous recombination deficiency (HRD).
- (2019) Julia Chen et al. JOURNAL OF CLINICAL ONCOLOGY
- Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial
- (2019) David A Palma et al. LANCET
- Pivotal Trial of Enfortumab Vedotin in Urothelial Carcinoma After Platinum and Anti-Programmed Death 1/Programmed Death Ligand 1 Therapy
- (2019) Jonathan E. Rosenberg et al. JOURNAL OF CLINICAL ONCOLOGY
- Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer
- (2019) Talia Golan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma
- (2019) Yohann Loriot et al. NEW ENGLAND JOURNAL OF MEDICINE
- Complications and Economic Burden Associated With Obtaining Tissue for Diagnosis and Molecular Analysis in Patients With Non–Small-Cell Lung Cancer in the United States
- (2019) Ronan J. Kelly et al. Journal of Oncology Practice
- Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma: How to Apply New Evidence in Clinical Practice
- (2019) Andrey Soares et al. ONCOLOGY
- LBA12_PRPROfound: Phase III study of olaparib versus enzalutamide or abiraterone for metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene alterations
- (2019) M Hussain et al. ANNALS OF ONCOLOGY
- Investigational MET inhibitors to treat Renal cell carcinoma
- (2019) Lakshminarayanan Nandagopal et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial
- (2019) Joaquin Mateo et al. LANCET ONCOLOGY
- Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA
- (2018) Neeraj Agarwal et al. CANCER
- Monitoring Treatment Response and Metastatic Relapse in Advanced Bladder Cancer by Liquid Biopsy Analysis
- (2018) Karin Birkenkamp-Demtröder et al. EUROPEAN UROLOGY
- Exceptional Response to Nivolumab Rechallenge in Metastatic Renal Cell Carcinoma with Parallel Changes in Genomic Profile
- (2018) Nazli Dizman et al. EUROPEAN UROLOGY
- Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide
- (2018) Emmanuel S. Antonarakis et al. EUROPEAN UROLOGY
- Challenges with biomarkers in cancer drug discovery and development
- (2018) Ecaterina Ileana Dumbrava et al. Expert Opinion on Drug Discovery
- Erdafitinib (ERDA; JNJ-42756493), a pan-fibroblast growth factor receptor (FGFR) inhibitor, in patients (pts) with metastatic or unresectable urothelial carcinoma (mUC) and FGFR alterations (FGFRa): Phase 2 continuous versus intermittent dosing.
- (2018) Yohann Loriot et al. JOURNAL OF CLINICAL ONCOLOGY
- Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer
- (2018) Daniel E. Spratt et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012
- (2018) Maha Hussain et al. JOURNAL OF CLINICAL ONCOLOGY
- Circulating Tumor Cell Number as a Response Measure of Prolonged Survival for Metastatic Castration-Resistant Prostate Cancer: A Comparison With Prostate-Specific Antigen Across Five Randomized Phase III Clinical Trials
- (2018) Glenn Heller et al. JOURNAL OF CLINICAL ONCOLOGY
- Relationship of tumor mutational burden (TMB) to immunotherapy response in metastatic renal cell carcinoma (mRCC).
- (2018) Manuel C. Maia et al. JOURNAL OF CLINICAL ONCOLOGY
- Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study
- (2018) Benjamin A Teply et al. LANCET ONCOLOGY
- Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma
- (2018) Arnaud Méjean et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma
- (2018) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden
- (2018) Matthew D. Hellmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prognostic association of plasma cell-free DNA-based androgen receptor amplification and circulating tumor cells in pre-chemotherapy metastatic castration-resistant prostate cancer patients
- (2018) Manish Kohli et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Circulating Tumor DNA Genomics Correlate with Resistance to Abiraterone and Enzalutamide in Prostate Cancer
- (2018) Matti Annala et al. Cancer Discovery
- BRAF inhibitors in metastatic non-small cell lung cancer
- (2018) Geòrgia Anguera et al. Journal of Thoracic Disease
- Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti–Programmed Cell Death 1 Antibodies
- (2018) Jenny H. Lee et al. JAMA Oncology
- Patient-Paired Sample Congruence Between 2 Commercial Liquid Biopsy Tests
- (2018) Gonzalo Torga et al. JAMA Oncology
- An Update on Predictive Biomarkers for Treatment Selection in Non-Small Cell Lung Cancer
- (2018) Tamkin Ahmadzada et al. Journal of Clinical Medicine
- Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer
- (2018) Daniel Nava Rodrigues et al. JOURNAL OF CLINICAL INVESTIGATION
- Economic impact of next generation sequencing vs sequential single-gene testing modalities to detect genomic alterations in metastatic non-small cell lung cancer using a decision analytic model.
- (2018) Nathan A. Pennell et al. JOURNAL OF CLINICAL ONCOLOGY
- Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab
- (2018) David R. Gandara et al. NATURE MEDICINE
- 163PAccurate measurement of tumor mutation burden in liquid biopsy (bTMB) using a 500 gene panel
- (2018) T Jiang et al. ANNALS OF ONCOLOGY
- 131PDevelopment and analytical validation of a plasma-based tumor mutational burden (TMB) score from next-generation sequencing panels
- (2018) K Quinn et al. ANNALS OF ONCOLOGY
- Efficacy of Radium-223 in Bone-metastatic Castration-resistant Prostate Cancer with and Without Homologous Repair Gene Defects
- (2018) Pedro Isaacsson Velho et al. EUROPEAN UROLOGY
- Perspectives on the current and emerging chemical androgen receptor antagonists for the treatment of prostate cancer
- (2018) Athanasios E. Dellis et al. EXPERT OPINION ON PHARMACOTHERAPY
- Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study
- (2018) Andrea Necchi et al. JOURNAL OF CLINICAL ONCOLOGY
- T1 bladder cancer: current considerations for diagnosis and management
- (2018) Brian Jordan et al. Nature Reviews Urology
- Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma
- (2018) Peiyong Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced detection of circulating tumor DNA by fragment size analysis
- (2018) Florent Mouliere et al. Science Translational Medicine
- Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
- (2018) Markus Mayrhofer et al. Genome Medicine
- Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients with Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib
- (2018) Axel Bex et al. JAMA Oncology
- Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss
- (2018) Johann S. de Bono et al. CLINICAL CANCER RESEARCH
- Evolution of Circulating Tumor DNA Profile from First-line to Subsequent Therapy in Metastatic Renal Cell Carcinoma
- (2017) Sumanta K. Pal et al. EUROPEAN UROLOGY
- Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer
- (2017) Emil Christensen et al. EUROPEAN UROLOGY
- EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016
- (2017) Marko Babjuk et al. EUROPEAN UROLOGY
- Using liquid biopsy to assess the genomic landscape of metastatic urothelial carcinoma
- (2017) T. Todenhöfer et al. EUROPEAN UROLOGY SUPPLEMENTS
- The feasibility of using mutation detection in ctDNA to assess tumor dynamics
- (2017) Xin Yi et al. INTERNATIONAL JOURNAL OF CANCER
- Circulating tumor (ct)-DNA alterations in advanced urothelial carcinoma: Association with outcomes and evolution with therapy.
- (2017) Petros Grivas et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide
- (2017) Emmanuel S. Antonarakis et al. JOURNAL OF CLINICAL ONCOLOGY
- Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial
- (2017) Toni K. Choueiri et al. JOURNAL OF CLINICAL ONCOLOGY
- Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer
- (2017) Alexander W Wyatt et al. JNCI-Journal of the National Cancer Institute
- Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/ASTRO/SUO Guideline
- (2017) Sam S. Chang et al. JOURNAL OF UROLOGY
- CT–Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield
- (2017) Michael G. Holmes et al. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
- Integrating liquid biopsies into the management of cancer
- (2017) Giulia Siravegna et al. Nature Reviews Clinical Oncology
- Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
- (2017) Tony S. Mok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Direct detection of early-stage cancers using circulating tumor DNA
- (2017) Jillian Phallen et al. Science Translational Medicine
- Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors
- (2017) David Quigley et al. Cancer Discovery
- Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition
- (2017) Jane Goodall et al. Cancer Discovery
- Establishing PNB-qPCR for quantifying minimal ctDNA concentrations during tumour resection
- (2017) T. Ehlert et al. Scientific Reports
- Precision oncology: Charting a path forward to broader deployment of genomic profiling
- (2017) Alison M. Schram et al. PLOS MEDICINE
- Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer
- (2017) Alexander W Wyatt et al. JNCI-Journal of the National Cancer Institute
- Genomic Analysis of Plasma Cell-Free DNA in Patients With Cancer
- (2017) Geoffrey R. Oxnard et al. JAMA Oncology
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015
- (2017) et al. JAMA Oncology
- Circulating Tumor DNA as Biomarkers for Cancer Detection
- (2017) Xiao Han et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Genomic alterations in circulating tumor DNA (ctDNA) are associated with clinical outcomes in treatment-naive metastatic castration-resistant prostate cancer (mCRPC) patients commencing androgen receptor (AR)-targeted therapy
- (2016) A.W. Wyatt et al. ANNALS OF ONCOLOGY
- EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method
- (2016) Kana Watanabe et al. Canadian Respiratory Journal
- Enfortumab Vedotin Antibody-Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models
- (2016) P. M. Challita-Eid et al. CANCER RESEARCH
- Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients
- (2016) Hongbiao Lu et al. CLINICA CHIMICA ACTA
- Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA
- (2016) J. C. Thompson et al. CLINICAL CANCER RESEARCH
- Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses
- (2016) David Lorente et al. Clinical Genitourinary Cancer
- Concentration and Methylation of Cell-Free DNA from Blood Plasma as Diagnostic Markers of Renal Cancer
- (2016) Inessa Skrypkina et al. DISEASE MARKERS
- Biallelic Inactivation of BRCA2 in Platinum-sensitive Metastatic Castration-resistant Prostate Cancer
- (2016) Heather H. Cheng et al. EUROPEAN UROLOGY
- Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer
- (2016) Karin Birkenkamp-Demtröder et al. EUROPEAN UROLOGY
- Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer
- (2016) David Lorente et al. EUROPEAN UROLOGY
- Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations
- (2016) Noura J. Choudhury et al. JOURNAL OF CLINICAL ONCOLOGY
- Association Between Plasma Genotyping and Outcomes of Treatment With Osimertinib (AZD9291) in Advanced Non–Small-Cell Lung Cancer
- (2016) Geoffrey R. Oxnard et al. JOURNAL OF CLINICAL ONCOLOGY
- Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
- (2016) Jonathan E Rosenberg et al. LANCET
- Dabrafenib plus trametinib in patients with previously treated BRAF V600E -mutant metastatic non-small cell lung cancer: an open-label, multicentre phase 2 trial
- (2016) David Planchard et al. LANCET ONCOLOGY
- Integrated digital error suppression for improved detection of circulating tumor DNA
- (2016) Aaron M Newman et al. NATURE BIOTECHNOLOGY
- Clonal evolution of chemotherapy-resistant urothelial carcinoma
- (2016) Bishoy M Faltas et al. NATURE GENETICS
- Circulating tumour cells as biomarkers of prostate, bladder and kidney cancer
- (2016) Michael A. Gorin et al. Nature Reviews Urology
- The effect of the USPSTF PSA screening recommendation on prostate cancer incidence patterns in the USA
- (2016) Katherine Fleshner et al. Nature Reviews Urology
- Costs and Outcomes Comparison of Tissue and Blood Based Biopsies for the Purpose of Biomarker Testing
- (2016) A Arnaud VALUE IN HEALTH
- Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial
- (2016) Tracy L. Stockley et al. Genome Medicine
- Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer
- (2016) Alexander W. Wyatt et al. JAMA Oncology
- Prospective Validation of Rapid Plasma Genotyping for the Detection ofEGFRandKRASMutations in Advanced Lung Cancer
- (2016) Adrian G. Sacher et al. JAMA Oncology
- Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer
- (2015) J. Tie et al. ANNALS OF ONCOLOGY
- Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer
- (2015) A. A. Azad et al. CLINICAL CANCER RESEARCH
- Detection and Dynamic Changes of EGFR Mutations from Circulating Tumor DNA as a Predictor of Survival Outcomes in NSCLC Patients Treated with First-line Intercalated Erlotinib and Chemotherapy
- (2015) T. Mok et al. CLINICAL CANCER RESEARCH
- Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer
- (2015) Elizabeth R. Plimack et al. EUROPEAN UROLOGY
- Circulating Tumor Cell Biomarker Panel As an Individual-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer
- (2015) Howard I. Scher et al. JOURNAL OF CLINICAL ONCOLOGY
- Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials
- (2015) Funda Meric-Bernstam et al. JOURNAL OF CLINICAL ONCOLOGY
- The Development of Intermediate Clinical Endpoints in Cancer of the Prostate (ICECaP)
- (2015) JNCI-Journal of the National Cancer Institute
- EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291
- (2015) Kenneth S. Thress et al. LUNG CANCER
- The evolutionary history of lethal metastatic prostate cancer
- (2015) Gunes Gundem et al. NATURE
- Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
- (2015) David M. Hyman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma
- (2015) Toni K. Choueiri et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
- (2015) Joaquin Mateo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- The Development of Intermediate Clinical Endpoints in Cancer of the Prostate (ICECaP)
- (2015) JNCI-Journal of the National Cancer Institute
- DNA repair mechanisms in cancer development and therapy
- (2015) Alessandro Torgovnick et al. Frontiers in Genetics
- Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA
- (2015) Richard B. Lanman et al. PLoS One
- Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle
- (2014) L. De Mattos-Arruda et al. ANNALS OF ONCOLOGY
- Circulating tumor cells and circulating tumor DNA for precision medicine: dream or reality?
- (2014) M. Ignatiadis et al. ANNALS OF ONCOLOGY
- Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer
- (2014) F. Rothé et al. ANNALS OF ONCOLOGY
- Surveillance or metastasis-directed Therapy for OligoMetastatic Prostate cancer recurrence (STOMP): study protocol for a randomized phase II trial
- (2014) Karel Decaestecker et al. BMC CANCER
- Noninvasive Detection of Response and Resistance in EGFR-Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA
- (2014) G. R. Oxnard et al. CLINICAL CANCER RESEARCH
- Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer
- (2014) J. A. Beaver et al. CLINICAL CANCER RESEARCH
- Quantitative Cell-Free Circulating BRAFV600E Mutation Analysis by Use of Droplet Digital PCR in the Follow-up of Patients with Melanoma Being Treated with BRAF Inhibitors
- (2014) M. F. Sanmamed et al. CLINICAL CHEMISTRY
- Circulating Tumor DNA as a Liquid Biopsy for Cancer
- (2014) E. Heitzer et al. CLINICAL CHEMISTRY
- An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
- (2014) Aaron M Newman et al. NATURE MEDICINE
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Correction: Anti-Inflammatory Thalidomide Improves Islet Grafts Survival and Functions in a Xenogenic Environment
- (2014) Chunguang Chen et al. PLoS One
- Imaging, procedural and clinical variables associated with tumor yield on bone biopsy in metastatic castration-resistant prostate cancer
- (2014) R R McKay et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
- (2014) C. Bettegowda et al. Science Translational Medicine
- Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma
- (2014) E. M. Van Allen et al. Cancer Discovery
- Circulating cell free DNA: Preanalytical considerations
- (2013) Safia El Messaoudi et al. CLINICA CHIMICA ACTA
- Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death
- (2013) James W. Hodge et al. INTERNATIONAL JOURNAL OF CANCER
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
- (2013) Sarah-Jane Dawson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Monitoring of Plasma Cell-Free DNA in Predicting Postoperative Recurrence of Clear Cell Renal Cell Carcinoma
- (2013) JingJing Wan et al. UROLOGIA INTERNATIONALIS
- Intratumor Heterogeneity: Evolution through Space and Time
- (2012) C. Swanton CANCER RESEARCH
- Quantitative Cell-Free DNA, KRAS, and BRAF Mutations in Plasma from Patients with Metastatic Colorectal Cancer during Treatment with Cetuximab and Irinotecan
- (2012) K.-L. G. Spindler et al. CLINICAL CANCER RESEARCH
- Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing
- (2012) K. C. A. Chan et al. CLINICAL CHEMISTRY
- Comparison of mortality outcomes after radical prostatectomy versus radiotherapy in patients with localized prostate cancer: A population-based analysis
- (2012) Firas Abdollah et al. INTERNATIONAL JOURNAL OF UROLOGY
- Use of Research Biopsies in Clinical Trials: Are Risks and Benefits Adequately Discussed?
- (2012) Michael J. Overman et al. JOURNAL OF CLINICAL ONCOLOGY
- Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
- (2012) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genome Sequencing Identifies a Basis for Everolimus Sensitivity
- (2012) G. Iyer et al. SCIENCE
- Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
- (2012) T. Forshew et al. Science Translational Medicine
- Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing
- (2012) R. J. Leary et al. Science Translational Medicine
- Cancer Response Criteria and Bone Metastases: RECIST 1.1, MDA and PERCIST
- (2012) Colleen M. Costelloe et al. Journal of Cancer
- High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number
- (2011) Benjamin J. Hindson et al. ANALYTICAL CHEMISTRY
- Multiplex Amplification Coupled with COLD-PCR and High Resolution Melting Enables Identification of Low-Abundance Mutations in Cancer Samples with Low DNA Content
- (2011) Coren A. Milbury et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Detection and quantification of rare mutations with massively parallel sequencing
- (2011) I. Kinde et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acquisition of metastatic tissue from patients with bone metastases from breast cancer
- (2010) J. F. Hilton et al. BREAST CANCER RESEARCH AND TREATMENT
- AACR-FDA-NCI Cancer Biomarkers Collaborative Consensus Report: Advancing the Use of Biomarkers in Cancer Drug Development
- (2010) S. N. Khleif et al. CLINICAL CANCER RESEARCH
- Detection of Low-Level KRAS Mutations Using PNA-Mediated Asymmetric PCR Clamping and Melting Curve Analysis with Unlabeled Probes
- (2010) Ji Eun Oh et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
- (2010) Michael C Haffner et al. NATURE GENETICS
- Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing
- (2010) R. J. Leary et al. Science Translational Medicine
- Histone modifications and chromatin organization in prostate cancer
- (2010) Zhong Chen et al. Epigenomics
- Cell-free Tumor DNA in Blood Plasma As a Marker for Circulating Tumor Cells in Prostate Cancer
- (2009) H. Schwarzenbach et al. CLINICAL CANCER RESEARCH
- Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
- (2009) Robert J. Motzer et al. JOURNAL OF CLINICAL ONCOLOGY
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
- (2009) Tony S. Mok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Diagnostic Role of Circulating Free Plasma DNA Detection in Patients With Localized Prostate Cancer
- (2008) Annalisa Altimari et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial
- (2008) Robert J Motzer et al. LANCET
- Circulating mutant DNA to assess tumor dynamics
- (2008) Frank Diehl et al. NATURE MEDICINE
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