The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation

Copper-Catalyzed Remote C(sp3 )−H Trifluoromethylation of Carboxamides and Sulfonamides

(2019) Zhonglin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Late-Stage Benzylic C(sp3)–H Trifluoromethylation

(2019) Haiwen Xiao et al.   Chem

Csp3–Csp3 Bond-Forming Reductive Elimination from Well-Defined Copper(III) Complexes

(2019) Matthew Paeth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Trifluoromethylation of Alkyl Bromides

(2019) David J. P. Kornfilt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective C(sp3 )−H Aerobic Oxidation Enabled by Decatungstate Photocatalysis in Flow

(2018) Gabriele Laudadio et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Renaissance of pyridine-oxazolines as chiral ligands for asymmetric catalysis

(2018) Guoqiang Yang et al.   CHEMICAL SOCIETY REVIEWS

Copper-Mediated Trifluoromethylation of Benzylic Csp3 −H Bonds

(2018) Matthew Paeth et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Evolution of Biocatalytic and Chemocatalytic C–H Functionalization Strategy in the Synthesis of Manzacidin C

(2018) Christian R. Zwick et al.   JOURNAL OF ORGANIC CHEMISTRY

Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2018) Jacob A. Kautzky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

Dual copper- and photoredox-catalysed reactions

(2018) Euan B. McLean et al.   TETRAHEDRON

Drug metabolism in drug discovery and development

(2018) Zhoupeng Zhang et al.   Acta Pharmaceutica Sinica B

sp3 C–H Arylation and Alkylation Enabled by the Synergy of Triplet Excited Ketones and Nickel Catalysts

(2018) Yangyang Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aqueous Benzylic C–H Trifluoromethylation for Late-Stage Functionalization

(2018) Shuo Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative sp3 C–N coupling via dual copper and photoredox catalysis

(2018) Yufan Liang et al.   NATURE

Direct arylation of strong aliphatic C–H bonds

(2018) Ian B. Perry et al.   NATURE

Trifluoromethylation of Alkyl Radicals in Aqueous Solution

(2017) Haigen Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2017) Xinqiang Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photocatalyzed Site-Selective C(sp3)–H Functionalization of Alkylpyridines at Non-Benzylic Positions

(2017) Takahide Fukuyama et al.   ORGANIC LETTERS

Remote C(sp3)–H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate

(2017) Melissa Lee et al.   ORGANIC LETTERS

Site-Selective C–H Functionalization by Decatungstate Anion Photocatalysis: Synergistic Control by Polar and Steric Effects Expands the Reaction Scope

(2017) Davide Ravelli et al.   ACS Catalysis

The merger of transition metal and photocatalysis

(2017) Jack Twilton et al.   Nature Reviews Chemistry

Decatungstate Anion for Photocatalyzed “Window Ledge” Reactions

(2016) Davide Ravelli et al.   ACCOUNTS OF CHEMICAL RESEARCH

Photochemical Nickel-Catalyzed C–H Arylation: Synthetic Scope and Mechanistic Investigations

(2016) Drew R. Heitz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C(sp3)–H Cross Coupling Enabled by Catalytic Generation of Chlorine Radicals

(2016) Benjamin J. Shields et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

(2016) M. H. Shaw et al.   SCIENCE

Unraveling the Key Features of the Reactive State of Decatungstate Anion in Hydrogen Atom Transfer (HAT) Photocatalysis

(2016) Vincent De Waele et al.   ACS Catalysis

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Platinum-Catalyzed, Terminal-Selective C(sp3)–H Oxidation of Aliphatic Amines

(2015) Melissa Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Remote Oxidation of Aliphatic C–H Bonds in Nitrogen-Containing Molecules

(2015) Jennifer M. Howell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acceptorless dehydrogenation of small molecules through cooperative base metal catalysis

(2015) Julian G. West et al.   Nature Communications

General Reaction Mode of Hypervalent Iodine Trifluoromethylation Reagent: A Density Functional Theory Study

(2015) Lin Ling et al.   ACS Catalysis

A Convenient Photocatalytic Fluorination of Unactivated CH Bonds

(2014) Shira D. Halperin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Distinct Mechanism of Oxidative Trifluoromethylation with a Well-Defined Cu(II) Fluoride Promoter: Hidden Catalysis

(2014) Noel Nebra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

(2013) Pascal Furet et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Characterization of β-Trifluoromethyl-Substituted Pyrrolidines

(2013) Vladimir S. Yarmolchuk et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The role of organometallic copper(iii) complexes in homogeneous catalysis

(2013) Alicia Casitas et al.   Chemical Science

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins

(2011) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed C(sp3)–C(sp3) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

(2011) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Innate C-H trifluoromethylation of heterocycles

(2011) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diamine ligands in copper-catalyzed reactions

(2010) David S. Surry et al.   Chemical Science

Synthesis and in vivo evaluation of 3-substituted gababutins

(2009) David C. Blakemore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Decatungstate as an efficient photocatalyst in organic chemistry

(2009) Manolis D. Tzirakis et al.   CHEMICAL SOCIETY REVIEWS