Genistin: A Novel Potent Anti-Adipogenic and Anti-Lipogenic Agent

Soy Isoflavones Ameliorate Fatty Acid Metabolism of Visceral Adipose Tissue by Increasing the AMPK Activity in Male Rats with Diet-Induced Obesity (DIO)

(2019) Tan et al.   MOLECULES

Orobol, an Enzyme-Convertible Product of Genistein, exerts Anti-Obesity Effects by Targeting Casein Kinase 1 Epsilon

(2019) Hee Yang et al.   Scientific Reports

3-Chloro-4,5-dihydroxybenzaldehyde inhibits adipogenesis in 3T3-L1 adipocytes by regulating expression of adipogenic transcription factors and AMPK activation

(2018) Min-Cheol Kang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Daidzein-rich isoflavone aglycones inhibit cell growth and inflammation in endometriosis

(2018) O. Takaoka et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Modulation of Adipocyte Differentiation and Proadipogenic Gene Expression by Sulforaphane, Genistein, and Docosahexaenoic Acid as a First Step to Counteract Obesity

(2018) Veronica Valli et al.   Oxidative Medicine and Cellular Longevity

Structure and Physiological Regulation of AMPK

(2018) Yan Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genistein Binding to Copper(II)—Solvent Dependence and Effects on Radical Scavenging

(2017) Jing Yang et al.   MOLECULES

Inhibitory effects of daidzein and genistein on trypsin: Insights from spectroscopic and molecular docking studies

(2016) Hua-jin Zeng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Metabolic programming of a beige adipocyte phenotype by genistein

(2016) Sadat A. Aziz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Targeting adipose tissue in the treatment of obesity-associated diabetes

(2016) Christine M. Kusminski et al.   NATURE REVIEWS DRUG DISCOVERY

Adipose tissue fibrosis, hypertrophy, and hyperplasia: Correlations with diabetes in human obesity

(2016) Lindsey A. Muir et al.   Obesity

Daidzein reduces the proliferation and adiposeness of 3T3-L1 preadipocytes via regulating adipogenic gene expression

(2016) Yang He et al.   Journal of Functional Foods

The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures

(2016) Yuri Sakamoto et al.   PLoS One

Soybean isoflavone treatment induces osteoblast differentiation and proliferation by regulating analysis of Wnt/β-catenin pathway

(2015) Fang Yu et al.   GENE

Theobromine inhibits differentiation of 3T3-L1 cells during the early stage of adipogenesis via AMPK and MAPK signaling pathways

(2015) Yeon Jeong Jang et al.   Food & Function

FABP4 Attenuates PPAR  and Adipogenesis and Is Inversely Correlated With PPAR  in Adipose Tissues

(2013) T. Garin-Shkolnik et al.   DIABETES

Daidzein, R-(+)equol and S-(−)equol inhibit the invasion of MDA-MB-231 breast cancer cells potentially via the down-regulation of matrix metalloproteinase-2

(2013) Pamela J. Magee et al.   EUROPEAN JOURNAL OF NUTRITION

A metabolite of daidzein, 6,7,4′-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K

(2013) Sang Gwon Seo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content

(2013) J. A. Rothwell et al.   Database-The Journal of Biological Databases and Curation

SREBP: a novel therapeutic target

(2012) X. Xiao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Genistein and daidzein, typical soy isoflavones, inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

(2012) Masayoshi Yanagisawa et al.   MOLECULAR NUTRITION & FOOD RESEARCH

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Antiadipogenic Effect of Dietary Apigenin through Activation of AMPK in 3T3-L1 Cells

(2011) Mafuyu Ono et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of cancer cell invasion and metastasis by genistein

(2010) Janet M. Pavese et al.   CANCER AND METASTASIS REVIEWS

Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/β-catenin signalling or lipolysis

(2010) M.-H. Kim et al.   CELL PROLIFERATION

Potential Health-modulating Effects of Isoflavones and Metabolites via Activation of PPAR and AhR

(2010) Svjetlana Medjakovic et al.   Nutrients

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

Isoflavone effect on gene expression profile and biomarkers of inflammation

(2009) M. Blay et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways

(2008) Jiyun Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genistein inhibits differentiation of primary human adipocytes

(2008) Hea Jin Park et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY