Metabolic-Hydroxy and Carboxy Functionalization of Alkyl Moieties in Drug Molecules: Prediction of Structure Influence and Pharmacologic Activity

Linking Aromatic Hydroxy Metabolic Functionalization of Drug Molecules to Structure and Pharmacologic Activity

(2018) Babiker El-Haj et al.   MOLECULES

PharmGKB summary

(2015) Liudmila L. Mazaleuskaya et al.   Pharmacogenetics and Genomics

Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants

(2015) Galvin Vredenburg et al.   TOXICOLOGY LETTERS

Mechanistic Insights into a Classic Wonder Drug—Aspirin

(2014) Jinping Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Early phytocannabinoid chemistry to endocannabinoids and beyond

(2014) Raphael Mechoulam et al.   NATURE REVIEWS NEUROSCIENCE

Deeper Insight into the Reducing Biotransformation of Bupropion in the Human Liver

(2013) Lucie Skarydova et al.   Drug Metabolism and Pharmacokinetics

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

(2013) Jun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How theories evolved concerning the mechanism of action of barbiturates

(2012) Wolfgang Löscher et al.   EPILEPSIA

Oxazaphosphorine bioactivation and detoxification: the role of xenobiotic receptors

(2012) Duan Wang et al.   Acta Pharmaceutica Sinica B

CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay

(2011) A. Iwamura et al.   DRUG METABOLISM AND DISPOSITION

Histamine and H1-antihistamines: Celebrating a century of progress

(2011) F. Estelle R. Simons et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Pharmacokinetics of Paliperidone Versus Risperidone

(2011) Jose de Leon et al.   PSYCHOSOMATICS

Pharmacologically active compounds in the environment and their chirality

(2010) Barbara Kasprzyk-Hordern   CHEMICAL SOCIETY REVIEWS

Antiplatelet Drugs – Do We Need New Options?

(2010) Sergio Coccheri   DRUGS

Medicinal potential of willow: A chemical perspective of aspirin discovery

(2010) Jassem G. Mahdi   Journal of Saudi Chemical Society

Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes

(2009) Paul R. Ortiz de Montellano   CHEMICAL REVIEWS

Antiplatelet Drugs

(2008) Carlo Patrono et al.   CHEST

Peptic Ulcerations Are Related to Systemic Rather Than Local Effects of Low-Dose Aspirin

(2008) Martijn G.H. van Oijen et al.   Clinical Gastroenterology and Hepatology

Physicochemical, Pharmacological and Pharmacokinetic Properties of the Zwitterionic Antihistamines Cetirizine and Levocetirizine

(2008) Chen Chen   CURRENT MEDICINAL CHEMISTRY