Dying tumor cell-derived exosomal miR-194-5p potentiates survival and repopulation of tumor repopulating cells upon radiotherapy in pancreatic cancer

Cancer statistics, 2019

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Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC

(2019) Lielian Zuo et al.   Molecular Therapy-Nucleic Acids

Hepatocyte-derived exosomal MiR-194 activates PMVECs and promotes angiogenesis in hepatopulmonary syndrome

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microRNA-193a stimulates pancreatic cancer cell repopulation and metastasis through modulating TGF-β2/TGF-βRIII signalings

(2018) Chi Fang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

(2018) Wei Yan et al.   NATURE CELL BIOLOGY

MicroRNA-focused CRISPR-Cas9 library screen reveals fitness-associated miRNAs

(2018) Jessica S. Kurata et al.   RNA

HMGB1 released by irradiated tumor cells promotes living tumor cell proliferation via paracrine effect

(2018) Sijia He et al.   Cell Death & Disease

The Ever-Evolving Concept of the Cancer Stem Cell in Pancreatic Cancer

(2018) Sandra Valle et al.   Cancers

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis

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Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma

(2017) Lindsey N. Kent et al.   JOURNAL OF CLINICAL INVESTIGATION

Cisplatin induces the release of extracellular vesicles from ovarian cancer cells that can induce invasiveness and drug resistance in bystander cells

(2017) Priya Samuel et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Overexpression of miR-194 Reverses HMGA2-driven Signatures in Colorectal Cancer

(2017) Hsin-Yi Chang et al.   Theranostics

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

(2016) R. Moschoi et al.   BLOOD

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

eIF4E-phosphorylation-mediated Sox2 upregulation promotes pancreatic tumor cell repopulation after irradiation

(2016) Yang Yu et al.   CANCER LETTERS

Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles

(2016) Jingwei Ma et al.   CELL RESEARCH

Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells

(2016) Yiting Tang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells

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Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury

(2016) Subhrajit Saha et al.   Nature Communications

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

(2016) Chi Lam Au Yeung et al.   Nature Communications

Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis

(2016) Deepa Rajamani et al.   Genome Medicine

Massive release of extracellular vesicles from cancer cells after photodynamic treatment or chemotherapy

(2016) Kelly Aubertin et al.   Scientific Reports

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

Approach to Patients With Pancreatic Cancer Without Detectable Metastases

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Therapy-induced tumour secretomes promote resistance and tumour progression

(2015) Anna C. Obenauf et al.   NATURE

Postoperative Prognosis Prediction of Pancreatic Cancer With Seven MicroRNAs

(2015) Kwang Hyuck Lee et al.   PANCREAS

KRAS-dependent sorting of miRNA to exosomes

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Dying tumor cells stimulate proliferation of living tumor cells via caspase-dependent protein kinase Cδ activation in pancreatic ductal adenocarcinoma

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Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

(2014) Antonina V. Kurtova et al.   NATURE

Upregulation of miR-194 contributes to tumor growth and progression in pancreatic ductal adenocarcinoma

(2014) JING ZHANG et al.   ONCOLOGY REPORTS

Dying Cells Protect Survivors from Radiation-Induced Cell Death in Drosophila

(2014) Amber Bilak et al.   PLoS Genetics

A Preclinical Xenograft Model Identifies Castration-Tolerant Cancer-Repopulating Cells in Localized Prostate Tumors

(2013) R. Toivanen et al.   Science Translational Medicine

Past, present and future of radiotherapy for the benefit of patients

(2012) Juliette Thariat et al.   Nature Reviews Clinical Oncology

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

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ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma

(2011) Michael P. Kim et al.   PLoS One

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2

(2009) A. Y.J. Li et al.   CANCER RESEARCH

E2F3 Is a Mediator of DNA Damage-Induced Apoptosis

(2009) L. A. Martinez et al.   MOLECULAR AND CELLULAR BIOLOGY

p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

(2008) C. J. Braun et al.   CANCER RESEARCH

Death through a tragedy: mitotic catastrophe

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