Tetraspanin 7 and its closest paralog tetraspanin 6: membrane organizers with key functions in brain development, viral infection, innate immunity, diabetes and cancer

Dendritic Cell Maturation Regulates TSPAN7 Function in HIV-1 Transfer to CD4+ T Lymphocytes

(2020) Brieuc P. Perot et al.   Frontiers in Cellular and Infection Microbiology

Autoimmunity to tetraspanin-7 in type 1 diabetes

(2020) Kerry A. McLaughlin et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Cytoplasmic ends of tetraspanin 7 harbour epitopes recognised by autoantibodies in type 1 diabetes

(2019) Anne Eugster et al.   DIABETOLOGIA

Manipulation of Mononuclear Phagocytes by HIV: Implications for Early Transmission Events

(2019) Kirstie Melissa Bertram et al.   Frontiers in Immunology

Tetraspanin CD9: A Key Regulator of Cell Adhesion in the Immune System

(2018) Raquel Reyes et al.   Frontiers in Immunology

Mechanisms for Cell-to-Cell Transmission of HIV-1

(2018) Lucie Bracq et al.   Frontiers in Immunology

Tetraspanins as Organizers of Antigen-Presenting Cell Function

(2018) Maria Laura Saiz et al.   Frontiers in Immunology

Antitumor Immunity Is Controlled by Tetraspanin Proteins

(2018) Fleur Schaper et al.   Frontiers in Immunology

Immune Targeting of Tetraspanins Involved in Cell Invasion and Metastasis

(2018) Felipe Vences-Catalán et al.   Frontiers in Immunology

Global Burden of Multiple Myeloma

(2018) Andrew J. Cowan et al.   JAMA Oncology

Tetraspanins, Another Piece in the HIV-1 Replication Puzzle

(2018) Henar Suárez et al.   Frontiers in Immunology

Damage-Associated Molecular Patterns in Inflammatory Diseases

(2018) Jong Seong Roh et al.   Immune Network

TSPAN7 promotes the migration and proliferation of lung cancer cells via epithelial-to-mesenchymal transition

(2018) Xianguo Wang et al.   OncoTargets and Therapy

Functional expression of dopamine D2 receptor is regulated by tetraspanin 7–mediated postendocytic trafficking

(2017) Seol-Ae Lee et al.   FASEB JOURNAL

Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments

(2017) Francesc X. Guix et al.   Molecular Neurodegeneration

Exosomal tetraspanins mediate cancer metastasis by altering host microenvironment

(2017) Jun Lu et al.   Oncotarget

T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes

(2017) Adam L. Burrack et al.   Frontiers in Endocrinology

Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity

(2017) Isabel H. Salas et al.   PLoS One

Tetraspanin 7 regulates sealing zone formation and the bone-resorbing activity of osteoclasts

(2016) Jun-Oh Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells

(2016) Mickaël M. Ménager et al.   CELL

The immunoglobulin-like superfamily member IGSF3 is a developmentally regulated protein that controls neuronal morphogenesis

(2016) Alessia Usardi et al.   Developmental Neurobiology

Identification of Tetraspanin-7 as a Target of Autoantibodies in Type 1 Diabetes

(2016) Kerry A. McLaughlin et al.   DIABETES

Tetraspanin 7 autoantibodies in type 1 diabetes

(2016) Denise Walther et al.   DIABETOLOGIA

Molecular mechanisms of regulation of Toll-like receptor signaling

(2016) Cynthia A. Leifer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

The Emerging Role of Tetraspanins in the Proteolytic Processing of the Amyloid Precursor Protein

(2016) Lisa Seipold et al.   Frontiers in Molecular Neuroscience

Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo

(2015) Chee Man Cheong et al.   EXPERIMENTAL CELL RESEARCH

A mechanistic overview of dendritic cell-mediated HIV-1 trans infection: the story so far

(2015) Suzanne DG Kijewski et al.   Future Virology

Targeted Next-Generation Sequencing Analysis of 1,000 Individuals with Intellectual Disability

(2015) Detelina Grozeva et al.   HUMAN MUTATION

The Role of Human Dendritic Cells in HIV-1 Infection

(2015) Zahra Ahmed et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tetraspanins at a glance

(2014) S. Charrin et al.   JOURNAL OF CELL SCIENCE

HIV-1 Nef and Vpu Are Functionally Redundant Broad-Spectrum Modulators of Cell Surface Receptors, Including Tetraspanins

(2014) C. Haller et al.   JOURNAL OF VIROLOGY

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Genes and pathways underlying regional and cell type changes in Alzheimer's disease

(2013) Jeremy A Miller et al.   Genome Medicine

Causes of Death of Patients With Lung Cancer

(2012) Larry Nichols et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Tetraspanin 6 (TSPAN6) Negatively Regulates Retinoic Acid-inducible Gene I-like Receptor-mediated Immune Signaling in a Ubiquitination-dependent Manner

(2012) Yetao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking

(2012) Silvia Bassani et al.   NEURON

Brain Transcriptome-Wide Screen for HIV-1 Nef Protein Interaction Partners Reveals Various Membrane-Associated Proteins

(2012) Ellen C. Kammula et al.   PLoS One

Pancreatic islet and progenitor cell surface markers with cell sorting potential

(2011) J. Hald et al.   DIABETOLOGIA

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases

(2011) Daniela Wuttig et al.   INTERNATIONAL JOURNAL OF CANCER

Duplicability of self-interacting human genes

(2010) Asa Perez-Bercoff et al.   BMC EVOLUTIONARY BIOLOGY

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

(2010) Koen Bossers et al.   BRAIN

Wegener’s granuloma harbors B lymphocytes with specificities against a proinflammatory transmembrane protein and a tetraspanin

(2010) Lorenz Thurner et al.   JOURNAL OF AUTOIMMUNITY

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

(2010) A Piton et al.   MOLECULAR PSYCHIATRY

Egress of HSV-1 capsid requires the interaction of VP26 and a cellular tetraspanin membrane protein

(2010) Lei Wang et al.   Virology Journal

Dendritic Cells and HIV-1 Trans-Infection

(2010) David McDonald   Viruses-Basel

Recurrent Rearrangements in Synaptic and Neurodevelopmental Genes and Shared Biologic Pathways in Schizophrenia, Autism, and Mental Retardation

(2009) Audrey Guilmatre et al.   ARCHIVES OF GENERAL PSYCHIATRY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Gene signatures of pulmonary metastases of renal cell carcinoma reflect the disease-free interval and the number of metastases per patient

(2009) Daniela Wuttig et al.   INTERNATIONAL JOURNAL OF CANCER

Appearance of new tetraspanin genes during vertebrate evolution

(2008) Antonio Garcia-España et al.   GENOMICS

A calculated response: control of inflammation by the innate immune system

(2008) Gregory M. Barton   JOURNAL OF CLINICAL INVESTIGATION

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Targeting of tetraspanin proteins — potential benefits and strategies

(2008) Martin E. Hemler   NATURE REVIEWS DRUG DISCOVERY

PrPC interacts with tetraspanin-7 through bovine PrP154–182 containing alpha-helix 1

(2007) Mingxiong Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS