Fructose Production and Metabolism in the Kidney

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats

(2019) Laura G. Sánchez-Lozada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-fructose corn syrup enhances intestinal tumor growth in mice

(2019) Marcus D. Goncalves et al.   SCIENCE

Are Liquid Sugars Different from Solid Sugar in Their Ability to Cause Metabolic Syndrome?

(2019) Gerhard Sundborn et al.   Obesity

The case for uric acid-lowering treatment in patients with hyperuricaemia and CKD

(2019) Yuka Sato et al.   Nature Reviews Nephrology

Fructose metabolism as a common evolutionary pathway of survival associated with climate change, food shortage and droughts

(2019) R. J. Johnson et al.   JOURNAL OF INTERNAL MEDICINE

Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation

(2018) Richard J. Johnson et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease

(2018) Thomas Jensen et al.   JOURNAL OF HEPATOLOGY

High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism

(2018) Miguel A. Lanaspa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Warburg Effect in Diabetic Kidney Disease

(2018) Guanshi Zhang et al.   SEMINARS IN NEPHROLOGY

Patterns of Beverages Consumed and Risk of Incident Kidney Disease

(2018) Casey M. Rebholz et al.   Clinical Journal of the American Society of Nephrology

Role of fructose and fructokinase in acute dehydration-induced vasopressin gene expression and secretion in mice

(2017) Zhilin Song (宋志林) et al.   JOURNAL OF NEUROPHYSIOLOGY

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

(2017) Thomas J. Park et al.   SCIENCE

Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice

(2017) Ana Andres-Hernando et al.   Nature Communications

Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy

(2016) J. Glaser et al.   Clinical Journal of the American Society of Nephrology

The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis

(2016) Mark A. Herman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease

(2015) Peter Mirtschink et al.   NATURE

Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy

(2014) M. A. Lanaspa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Potential health concerns of dietary phosphorus: cancer, obesity, and hypertension

(2013) John J.B. Anderson   Annals of the New York Academy of Sciences

Fructokinase activity mediates dehydration-induced renal injury

(2013) Carlos A. Roncal Jimenez et al.   KIDNEY INTERNATIONAL

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

(2013) Miguel A. Lanaspa et al.   Nature Communications

Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neurop

(2012) N. Hotta et al.   DIABETIC MEDICINE

Hibernating bears (Ursidae): metabolic magicians of definite interest for the nephrologist

(2012) Peter Stenvinkel et al.   KIDNEY INTERNATIONAL

Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver

(2012) Miguel A. Lanaspa et al.   PLoS One

Functional roles of fructose

(2012) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice

(2012) T. Ishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome

(2011) W. Baldwin et al.   DIABETES

Low-fructose diet lowers blood pressure and inflammation in patients with chronic kidney disease

(2011) A. Brymora et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Associations of Sugar and Artificially Sweetened Soda with Albuminuria and Kidney Function Decline in Women

(2010) J. Lin et al.   Clinical Journal of the American Society of Nephrology

Endothelial dysfunction as a potential contributor in diabetic nephropathy

(2010) Takahiko Nakagawa et al.   Nature Reviews Nephrology

Sugar-sweetened beverage consumption and the progression of chronic kidney disease in the Multi-Ethnic Study of Atherosclerosis (MESA)

(2009) Andrew S Bomback et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Aldose Reductase Inhibitor, Epalrestat, Reduces Lipid Hydroperoxides in Type 2 Diabetes

(2009) Chie OHMURA et al.   ENDOCRINE JOURNAL

Ketohexokinase-Dependent Metabolism of Fructose Induces Proinflammatory Mediators in Proximal Tubular Cells

(2009) P. Cirillo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of the fructose transporter GLUT5 in health and disease

(2008) Veronique Douard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fructose Induces the Inflammatory Molecule ICAM-1 in Endothelial Cells

(2008) O. Glushakova et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sugary Soda Consumption and Albuminuria: Results from the National Health and Nutrition Examination Survey, 1999–2004

(2008) David A. Shoham et al.   PLoS One