Therapeutic potentials of NOP and MOP receptor coactivation for the treatment of pain and opioid abuse
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Therapeutic potentials of NOP and MOP receptor coactivation for the treatment of pain and opioid abuse
Authors
Keywords
-
Journal
JOURNAL OF NEUROSCIENCE RESEARCH
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-04-07
DOI
10.1002/jnr.24624
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates
- (2019) Norikazu Kiguchi et al. BRITISH JOURNAL OF ANAESTHESIA
- Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys
- (2019) Shawn M. Flynn et al. NEUROPSYCHOPHARMACOLOGY
- A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward
- (2019) Kyle E. Parker et al. CELL
- BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine
- (2019) Po-Kuan Chao et al. NEUROPHARMACOLOGY
- Analysis of the distribution of spinal NOP receptors in a chronic pain model using NOP-eGFP knock-in mice
- (2018) Akihiko Ozawa et al. BRITISH JOURNAL OF PHARMACOLOGY
- Nociceptin/orphanin FQ opioid peptide (NOP) receptor and µ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain
- (2018) Klaus Schiene et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Peptide welding technology – A simple strategy for generating innovative ligands for G protein coupled receptors
- (2018) Girolamo Calo’ et al. PEPTIDES
- Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic
- (2018) G. Calo' et al. BRITISH JOURNAL OF ANAESTHESIA
- A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates
- (2018) Huiping Ding et al. Science Translational Medicine
- Cancer-related chronic pain: Investigation of the novel analgesic drug candidate cebranopadol in a randomized, double-blind, noninferiority trial
- (2018) Marie-Henriette Eerdekens et al. EUROPEAN JOURNAL OF PAIN
- Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13)
- (2017) Maria Camilla Cerlesi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The Role of Science in Addressing the Opioid Crisis
- (2017) Nora D. Volkow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cebranopadol, a novel first-in-class analgesic drug candidate
- (2017) Annette Christoph et al. PAIN
- A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism
- (2017) Anna Fantinati et al. Scientific Reports
- Prescription Opioid Misuse, Abuse, and Treatment in the United States: An Update
- (2016) Kathleen T. Brady et al. AMERICAN JOURNAL OF PSYCHIATRY
- Cebranopadol: novel dual opioid/NOP receptor agonist analgesic
- (2016) R. B. Raffa et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility
- (2016) Nurulain T. Zaveri JOURNAL OF MEDICINAL CHEMISTRY
- Opioid Abuse in Chronic Pain — Misconceptions and Mitigation Strategies
- (2016) Nora D. Volkow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nociceptin/orphanin FQ receptor expression in clinical pain disorders and functional effects in cultured neurons
- (2016) Praveen Anand et al. PAIN
- A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates
- (2016) Huiping Ding et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Supraspinal actions of nociceptin/orphanin FQ, morphine and substance P in regulating pain and itch in non-human primates
- (2015) H Ding et al. BRITISH JOURNAL OF PHARMACOLOGY
- Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys
- (2015) A Rizzi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mechanical hyperalgesia in rats with diabetic polyneuropathy is selectively inhibited by local peripheral nociceptin/orphanin FQ receptor and µ-opioid receptor agonism
- (2015) Klaus Schiene et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization
- (2015) Akihiko Ozawa et al. JOURNAL OF NEUROSCIENCE
- Understanding opioid reward
- (2015) Howard L. Fields et al. TRENDS IN NEUROSCIENCES
- Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates
- (2015) Heeseung Lee et al. Scientific Reports
- The global epidemiology and burden of opioid dependence: results from the global burden of disease 2010 study
- (2014) Louisa Degenhardt et al. ADDICTION
- Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists
- (2014) W Schröder et al. BRITISH JOURNAL OF PHARMACOLOGY
- Challenges for opioid receptor nomenclature: IUPHAR Review 9
- (2014) Brian M Cox et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats
- (2014) Devki D. Sukhtankar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol
- (2014) Stefan Schunk et al. ACS Medicinal Chemistry Letters
- Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans
- (2013) Talakad G. Lohith et al. NEUROIMAGE
- Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain
- (2013) Devki D. Sukhtankar et al. PSYCHOPHARMACOLOGY
- The Therapeutic Potential of Nociceptin/Orphanin FQ Receptor Agonists as Analgesics without Abuse Liability
- (2012) Ann P. Lin et al. ACS Chemical Neuroscience
- [Dmt1]N/OFQ(1-13)-NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist
- (2012) S Molinari et al. BRITISH JOURNAL OF PHARMACOLOGY
- Retrodialysis of N/OFQ into the nucleus accumbens shell blocks cocaine-induced increases in extracellular dopamine and locomotor activity
- (2012) Jacqueline Vazquez-DeRose et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Serine 363 Is Required for Nociceptin/Orphanin FQ Opioid Receptor (NOPR) Desensitization, Internalization, and Arrestin Signaling
- (2012) Nancy R. Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brain and Whole-Body Imaging of Nociceptin/Orphanin FQ Peptide Receptor in Humans Using the PET Ligand 11C-NOP-1A
- (2012) T. G. Lohith et al. JOURNAL OF NUCLEAR MEDICINE
- Structure of the δ-opioid receptor bound to naltrindole
- (2012) Sébastien Granier et al. NATURE
- Structure of the human κ-opioid receptor in complex with JDTic
- (2012) Huixian Wu et al. NATURE
- Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
- (2012) Aaron A. Thompson et al. NATURE
- Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
- (2012) Aashish Manglik et al. NATURE
- The Nociceptin/Orphanin FQ Receptor (NOP) as a Target for Drug Abuse Medications
- (2011) Nurulain T. Zaveri CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors
- (2011) Y. Kimura et al. JOURNAL OF NUCLEAR MEDICINE
- UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor
- (2010) Girolamo Calo' et al. CNS Neuroscience & Therapeutics
- Effects of the NOP receptor agonist Ro65-6570 on the acquisition of opiate- and psychostimulant-induced conditioned place preference in rats
- (2010) Kris Rutten et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The First Universal Opioid Ligand, (2S)-2-[(5R,6R,7R,14S)-N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol (BU08028): Characterization of the In Vitro Profile and In Vivo Behavioral Effects in Mouse Models of Acute Pain and Cocaine-Induced Reward
- (2010) T. V. Khroyan et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys
- (2010) Christopher A. Podlesnik et al. PSYCHOPHARMACOLOGY
- Antinociceptive Effects of Nociceptin/Orphanin FQ Administered Intrathecally in Monkeys
- (2009) Mei-Chuan Ko et al. JOURNAL OF PAIN
- Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112
- (2009) Eric Hu et al. PAIN
- Coupling Specificity of NOP Opioid Receptors to Pertussis-Toxin-Sensitive Gα Proteins in Adult Rat Stellate Ganglion Neurons Using Small Interference RNA
- (2008) Wojciech Margas et al. JOURNAL OF NEUROPHYSIOLOGY
- The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential
- (2008) David G. Lambert NATURE REVIEWS DRUG DISCOVERY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started