Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells

Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine

(2019) Amanda R. Burmeister et al.   Journal of Neuroinflammation

RIG-I activation is critical for responsiveness to checkpoint blockade

(2019) Simon Heidegger et al.   Science Immunology

Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles

(2018) Enping Hong et al.   NANO LETTERS

Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways

(2017) Kai Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P

(2017) Amanda R. Burmeister et al.   Journal of Neuroinflammation

Versatile RNA tetra-U helix linking motif as a toolkit for nucleic acid nanotechnology

(2017) My N. Bui et al.   Nanomedicine-Nanotechnology Biology and Medicine

Human microglia and astrocytes express cGAS-STING viral sensing components

(2017) Austin M. Jeffries et al.   NEUROSCIENCE LETTERS

Programmable Nucleic Acid Based Polygons with Controlled Neuroimmunomodulatory Properties for Predictive QSAR Modeling

(2017) Morgan Brittany Johnson et al.   Small

Cutting Edge: The RIG-I Ligand 3pRNA Potently Improves CTL Cross-Priming and Facilitates Antiviral Vaccination

(2016) Katharina Hochheiser et al.   JOURNAL OF IMMUNOLOGY

Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system

(2016) Yoelvis Garcia-Mesa et al.   JOURNAL OF NEUROVIROLOGY

MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis

(2016) Jincun Zhao et al.   JOURNAL OF VIROLOGY

Programmable RNA microstructures for coordinated delivery of siRNAs

(2016) Jaimie Marie Stewart et al.   Nanoscale

RIG-I is required for VSV-induced cytokine production by murine glia and acts in combination with DAI to initiate responses to HSV-1

(2015) Emma K. Crill et al.   GLIA

Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes

(2015) Carla Marinelli et al.   Journal of Neuroinflammation

In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member

(2014) Ian D. Cooley et al.   GLIA

Neurogenic Exacerbation of Microglial and Astrocyte Responses to Neisseria meningitidis and Borrelia burgdorferi

(2014) V. S. Chauhan et al.   JOURNAL OF IMMUNOLOGY

Multifunctional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   NANO LETTERS

RIG-I Detects mRNA of Intracellular Salmonella enterica Serovar Typhimurium during Bacterial Infection

(2014) M. Schmolke et al.   mBio

Roles of TLR3 and RIG-I in Mediating the Inflammatory Response in Mouse Microglia following Japanese Encephalitis Virus Infection

(2014) Rong Jiang et al.   Journal of Immunology Research

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

Dephosphorylation of the RNA Sensors RIG-I and MDA5 by the Phosphatase PP1 Is Essential for Innate Immune Signaling

(2013) Effi Wies et al.   IMMUNITY

Fusobacterium nucleatum Activates the Immune Response through Retinoic Acid–Inducible Gene I

(2013) P. Lee et al.   JOURNAL OF DENTAL RESEARCH

The Essential, Nonredundant Roles of RIG-I and MDA5 in Detecting and Controlling West Nile Virus Infection

(2013) J. S. Errett et al.   JOURNAL OF VIROLOGY

RIG-I Detects Triphosphorylated RNA of Listeria monocytogenes during Infection in Non-Immune Cells

(2013) Cristina Amparo Hagmann et al.   PLoS One

RIG-I detects infection with liveListeriaby sensing secreted bacterial nucleic acids

(2012) Zeinab Abdullah et al.   EMBO JOURNAL

A Sendai Virus-Derived RNA Agonist of RIG-I as a Virus Vaccine Adjuvant

(2012) L. Martínez-Gil et al.   JOURNAL OF VIROLOGY

IFNγ Inhibits the Cytosolic Replication of Shigella flexneri via the Cytoplasmic RNA Sensor RIG-I

(2012) Stephanie P. Jehl et al.   PLoS Pathogens

Prophylactic and Therapeutic Targeting of the Neurokinin-1 Receptor Limits Neuroinflammation in a Murine Model of Pneumococcal Meningitis

(2011) V. S. Chauhan et al.   JOURNAL OF IMMUNOLOGY

A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells

(2011) Samantha R Furr et al.   Journal of Neuroinflammation

Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine

(2011) Kirill A Afonin et al.   Nature Protocols

NOD2 mediates inflammatory responses of primary murine glia toStreptococcus pneumoniae

(2010) Xinjie Liu et al.   GLIA

RIG-I mediates nonsegmented negative-sense RNA virus-induced inflammatory immune responses of primary human astrocytes

(2010) Samantha R. Furr et al.   GLIA

NOD2 contributes to the inflammatory responses of primary murine microglia and astrocytes to Staphylococcus aureus

(2010) Xinjie Liu et al.   NEUROSCIENCE LETTERS

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

(2009) D. Uzri et al.   JOURNAL OF VIROLOGY

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

(2009) Andrea Ablasser et al.   NATURE IMMUNOLOGY

Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila

(2009) Kathryn M. Monroe et al.   PLoS Pathogens

NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens

(2008) Vinita S. Chauhan et al.   GLIA

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of retinoic acid–inducible gene-I expression in primary murine glia following exposure to vesicular stomatitis virus

(2008) Samantha R Furr et al.   JOURNAL OF NEUROVIROLOGY

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

(2008) Takeshi Saito et al.   NATURE