Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

Title
Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 63, Issue 9, Pages 4908-4928
Publisher
American Chemical Society (ACS)
Online
2020-04-23
DOI
10.1021/acs.jmedchem.0c00339

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