Rapid protein immobilization for thin film continuous flow biocatalysis

The synthesis of di-carboxylate esters using continuous flow vortex fluidics

(2016) Joshua Britton et al.   GREEN CHEMISTRY

Stereocontrol within polyketide assembly lines

(2016) Adrian T. Keatinge-Clay   NATURAL PRODUCT REPORTS

Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models

(2016) Sheel C. Dodani et al.   Nature Chemistry

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system

(2016) A. Adamo et al.   SCIENCE

Enzymatic Synthesis of Optically Active Lactones via Asymmetric Bioreduction using Ene-Reductases from the Old Yellow Enzyme Family

(2015) Nikolaus G. Turrini et al.   ADVANCED SYNTHESIS & CATALYSIS

Organic Synthesis: March of the Machines

(2015) Steven V. Ley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media

(2015) Hirofumi Sato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Oxidation of Methane

(2015) Sarah Sirajuddin et al.   BIOCHEMISTRY

Strategies for the one-step immobilization–purification of enzymes as industrial biocatalysts

(2015) Oveimar Barbosa et al.   BIOTECHNOLOGY ADVANCES

Industrial applications of enzyme biocatalysis: Current status and future aspects

(2015) Jung-Min Choi et al.   BIOTECHNOLOGY ADVANCES

Application of magnetic nanoparticles in smart enzyme immobilization

(2015) Hamideh Vaghari et al.   BIOTECHNOLOGY LETTERS

Shear-Stress-Mediated Refolding of Proteins from Aggregates and Inclusion Bodies

(2015) Tom Z. Yuan et al.   CHEMBIOCHEM

Rapid Vortex Fluidics: Continuous Flow Synthesis of Amides and Local Anesthetic Lidocaine

(2015) Joshua Britton et al.   CHEMISTRY-A EUROPEAN JOURNAL

Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization

(2015) Giang K. T. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

P450-catalyzed regio- and stereoselective oxidative hydroxylation of disubstituted cyclohexanes: creation of three centers of chirality in a single CH-activation event

(2015) Adriana Ilie et al.   TETRAHEDRON

Continuous flow Fischer esterifications harnessing vibrational-coupled thin film fluidics

(2015) Joshua Britton et al.   RSC Advances

Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active-Site Evolution of a Cytochrome P450

(2015) Christopher C. Farwell et al.   ACS Central Science

Accelerating Spirocyclic Polyketide Synthesis using Flow Chemistry

(2014) Sean Newton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progress in nanobiocatalysis for enzyme immobilization and its application

(2014) Kyoungseon Min et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Immobilization as a Strategy for Improving Enzyme Properties-Application to Oxidoreductases

(2014) Urszula Guzik et al.   MOLECULES

Continuous Flow Synthesis of Chiral Amines in Organic Solvents: Immobilization of E. coli Cells Containing Both ω-Transaminase and PLP

(2014) Leandro H. Andrade et al.   ORGANIC LETTERS

Enzyme immobilisation in biocatalysis: why, what and how

(2013) Roger A. Sheldon et al.   CHEMICAL SOCIETY REVIEWS

Conformational changes of enzymes upon immobilisation

(2013) Francesco Secundo   CHEMICAL SOCIETY REVIEWS

Computational design of ligand-binding proteins with high affinity and selectivity

(2013) Christine E. Tinberg et al.   NATURE

Strategies for Stabilization of Enzymes in Organic Solvents

(2013) Veronika Stepankova et al.   ACS Catalysis

Recent Advances in Asymmetric Catalysis in Flow

(2013) Dongbo Zhao et al.   ACS Catalysis

Glutaraldehyde in bio-catalysts design: a useful crosslinker and a versatile tool in enzyme immobilization

(2013) Oveimar Barbosa et al.   RSC Advances

Modifying enzyme activity and selectivity by immobilization

(2012) Rafael C. Rodrigues et al.   CHEMICAL SOCIETY REVIEWS

Stereoselective Chemoenzymatic Synthesis of Enantiopure 2-(1H-imidazol-yl)cycloalkanols under Continuous Flow Conditions

(2012) Raúl Porcar et al.   ACS Catalysis

Potential of Different Enzyme Immobilization Strategies to Improve Enzyme Performance

(2011) Cristina Garcia-Galan et al.   ADVANCED SYNTHESIS & CATALYSIS

Microwave-Assisted and Continuous Flow Multistep Synthesis of 4-(Pyrazol-1-yl)carboxanilides

(2011) David Obermayer et al.   JOURNAL OF ORGANIC CHEMISTRY

The Continuous-Flow Synthesis of Ibuprofen

(2009) Andrew R. Bogdan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Exploring protein fitness landscapes by directed evolution

(2009) Philip A. Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fully Automated Continuous Flow Synthesis of Highly Functionalized Imidazo[1,2-a] Heterocycles

(2009) Ananda Herath et al.   ORGANIC LETTERS